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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 104.4
Min nTPM: 27.3
Std nTPM: 18.8
Median nTPM:
142_1
61 years, female
104.4
313_1
79 years, female
103.4
501_1
88 years, male
101.3
2_1
77 years, female
100.0
17_1
71 years, male
98.7
4_1
88 years, female
93.8
162_1
79 years, female
93.8
42_1
85 years, male
92.4
119_1
70 years, female
92.2
153_1
70 years, female
89.8
308_1
70 years, female
89.2
109_1
81 years, female
88.4
117_1
61 years, male
87.1
322_1
76 years, male
87.0
139_1
64 years, female
83.9
466_1
57 years, female
82.8
495_1
57 years, female
82.4
120_1
70 years, female
81.0
43_1
64 years, female
80.7
415_1
77 years, female
80.0
414_1
84 years, female
79.4
491_1
89 years, female
79.4
126_1
63 years, male
78.1
137_1
83 years, male
77.9
324_1
76 years, male
76.8
526_1
61 years, male
76.1
9_1
66 years, female
74.9
145_1
84 years, male
74.3
518_1
75 years, female
74.0
18_1
88 years, male
73.1
413_1
59 years, female
72.2
315_1
62 years, female
72.1
351_1
91 years, male
72.1
377_1
82 years, female
72.1
396_1
62 years, male
72.1
6_1
73 years, female
71.8
384_1
83 years, male
71.8
173_1
67 years, male
70.5
490_1
67 years, female
70.3
288_1
66 years, female
70.0
266_1
85 years, male
69.5
506_1
65 years, male
69.3
307_1
66 years, female
68.9
356_1
87 years, female
68.8
311_1
78 years, male
68.7
350_1
84 years, female
68.7
189_1
76 years, male
68.1
452_1
88 years, female
66.5
468_1
89 years, male
66.4
35_1
74 years, female
65.8
335_1
73 years, female
65.7
81_1
67 years, male
65.6
293_1
68 years, female
65.3
375_1
74 years, female
64.1
41_1
94 years, female
64.0
379_1
60 years, male
63.3
376_1
75 years, female
61.4
314_1
67 years, male
60.2
447_1
81 years, male
59.3
394_1
75 years, female
59.2
32_1
67 years, male
58.8
89_1
63 years, male
58.8
149_1
88 years, male
58.8
115_1
83 years, male
58.7
316_1
62 years, male
58.2
320_1
89 years, female
57.3
317_1
60 years, male
57.2
354_1
81 years, female
57.0
243_1
75 years, male
56.8
292_1
71 years, male
56.0
99_1
64 years, male
55.2
319_1
81 years, male
53.9
286_1
68 years, female
52.0
389_1
86 years, female
51.8
353_1
82 years, female
51.0
406_1
79 years, male
50.9
404_1
82 years, female
49.8
246_1
77 years, male
49.6
251_1
78 years, male
49.0
218_1
71 years, female
48.3
265_1
87 years, male
48.3
177_1
74 years, male
48.1
352_1
62 years, male
47.2
254_1
77 years, female
46.3
318_1
68 years, male
46.1
349_1
83 years, male
45.5
295_1
61 years, female
45.0
425_1
59 years, female
44.4
499_1
55 years, female
44.1
480_1
63 years, male
40.7
172_1
72 years, female
40.2
517_1
88 years, male
40.2
503_1
68 years, male
36.8
264_1
73 years, female
36.0
348_1
84 years, male
36.0
386_1
76 years, male
34.7
291_1
76 years, male
34.5
405_1
91 years, male
33.2
217_1
76 years, male
32.2
237_1
82 years, male
31.8
355_1
70 years, female
31.8
347_1
72 years, male
31.4
229_1
69 years, female
30.8
163_1
78 years, male
28.4
321_1
62 years, female
27.3
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
