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DBNDD2
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:853.0 nTPM
HPA:853.0 nTPM
FANTOM5:505.5 Scaled Tags Per Million
Pig:60.5 nTPM
Allen mouse:12.7 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 853.0
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 758.5
2188 Female, age 91, both hemispheres 840.0
2301 Female, age 85, both hemispheres 811.0
2090 Male, age 80, both hemispheres 772.5
1984 Male, age 76, both hemispheres 610.6
Dorsal cochlear nucleus
nTPM: 717.4
2378 Male, age 80, both hemispheres 766.6
2187 Female, age 91, both hemispheres 750.7
2802 Male, age 74, right hemisphere 729.9
2370 Male, age 61, both hemispheres 685.4
2058 Male, age 76, both hemispheres 654.3
Dorsal tegmental nucleus
nTPM: 666.6
2083 Male, age 80, both hemispheres 766.7
2326 Male, age 74, both hemispheres 695.8
1936 Male, age 76, left hemisphere 609.2
2358 Male, age 61, both hemispheres 594.6
Dorsolateral tegmental area
nTPM: 693.1
2751 Female, age 85, both hemispheres 818.0
2654 Male, age 80, both hemispheres 763.3
2337 Male, age 61, both hemispheres 712.9
2360 Male, age 74, both hemispheres 612.1
2141 Male, age 76, both hemispheres 559.1
Kolliker-Fuse nucleus
nTPM: 743.9
2793 Female, age 91, left hemisphere 932.0
2163 Male, age 80, both hemispheres 690.9
2315 Male, age 76, right hemisphere 608.9
Lateral lemniscal nuclei
nTPM: 730.8
2320 Female, age 91, left hemisphere 824.5
2036 Male, age 80, both hemispheres 751.4
2746 Female, age 85, left hemisphere 718.0
2169 Male, age 76, both hemispheres 701.2
2453 Male, age 74, right hemisphere 658.8
Lateral parabrachial nucleus
nTPM: 802.3
2792 Male, age 76, both hemispheres 1037.9
2013 Male, age 80, both hemispheres 794.0
2790 Male, age 61, both hemispheres 720.7
2139 Female, age 85, right hemisphere 656.7
Lateral vestibular nucleus
nTPM: 705.1
2311 Male, age 80, both hemispheres 743.6
2184 Male, age 76, both hemispheres 666.5
Locus coeruleus
nTPM: 572.0
2720 Male, age 74, both hemispheres 619.7
2162 Male, age 80, both hemispheres 615.9
2317 Female, age 72, unknown 575.3
2788 Male, age 74, unknown 565.3
2123 Female, age 91, both hemispheres 562.3
2014 Male, age 55, unknown 545.5
1980 Male, age 76, both hemispheres 520.2
Medial olivary nucleus
nTPM: 853.0
1943 Male, age 61, both hemispheres 1010.7
1962 Male, age 76, both hemispheres 838.1
2851 Male, age 80, both hemispheres 794.8
2138 Female, age 91, both hemispheres 768.5
Medial parabrachial nucleus
nTPM: 740.7
2170 Female, age 91, both hemispheres 803.6
2463 Female, age 85, right hemisphere 774.0
2854 Male, age 80, both hemispheres 751.5
2156 Male, age 61, both hemispheres 696.5
2786 Male, age 76, both hemispheres 677.8
Medial periolivary nuclei
nTPM: 707.0
2081 Male, age 80, both hemispheres 754.9
2458 Female, age 91, both hemispheres 750.2
2791 Male, age 74, right hemisphere 732.8
2063 Male, age 76, both hemispheres 697.5
2171 Female, age 85, both hemispheres 599.7
Motor facial nucleus
nTPM: 726.3
2697 Female, age 85, both hemispheres 810.8
2126 Male, age 61, both hemispheres 766.3
2365 Male, age 74, right hemisphere 759.7
2795 Female, age 91, both hemispheres 695.0
2327 Male, age 80, both hemispheres 677.0
2062 Male, age 76, both hemispheres 649.1
Motor trigeminal nucleus
nTPM: 698.1
2560 Male, age 74, both hemispheres 747.2
2321 Female, age 91, both hemispheres 721.3
2079 Male, age 80, both hemispheres 687.7
2309 Male, age 76, both hemispheres 676.6
2335 Male, age 61, both hemispheres 657.5
Nuclei of the trapezoid body
nTPM: 679.4
2166 Male, age 80, both hemispheres 745.3
2368 Female, age 91, both hemispheres 720.8
2159 Male, age 61, both hemispheres 680.4
1983 Male, age 76, both hemispheres 675.7
2735 Female, age 85, both hemispheres 574.6
Paramedian reticular nucleus
nTPM: 705.4
2050 Female, age 85, both hemispheres 725.3
2052 Male, age 76, both hemispheres 722.4
2057 Male, age 80, both hemispheres 720.2
2313 Male, age 61, both hemispheres 653.5
Pontine nuclei
nTPM: 750.2
2454 Male, age 74, left hemisphere 891.5
2319 Female, age 91, both hemispheres 851.6
2109 Female, age 72, unknown 780.6
1863 Male, age 55, unknown 748.3
2115 Male, age 80, left hemisphere 720.4
1968 Male, age 76, left hemisphere 718.0
2787 Female, age 85, both hemispheres 657.5
2727 Male, age 61, right hemisphere 633.8
Pontine raphe nucleus
nTPM: 630.9
2122 Female, age 85, midline 642.9
2853 Male, age 76, midline 619.0
Posteroventral cochlear nucleus
nTPM: 790.4
2135 Female, age 91, both hemispheres 922.0
2341 Male, age 80, both hemispheres 888.3
2371 Male, age 61, both hemispheres 759.7
2070 Male, age 76, both hemispheres 741.6
2752 Female, age 85, both hemispheres 640.2
Principal sensory trigeminal nucleus
nTPM: 692.7
2367 Female, age 91, left hemisphere 856.3
2008 Male, age 80, left hemisphere 656.1
2324 Male, age 76, both hemispheres 636.7
2158 Male, age 61, both hemispheres 621.9
Reticular pontine nucleus, caudal
nTPM: 760.8
2457 Female, age 91, both hemispheres 805.3
2559 Male, age 74, both hemispheres 804.3
2092 Male, age 76, both hemispheres 762.2
2332 Male, age 80, right hemisphere 671.3
Reticular pontine nucleus, oral
nTPM: 788.1
2366 Female, age 91, both hemispheres 901.0
2361 Male, age 74, both hemispheres 810.5
1939 Male, age 80, both hemispheres 770.6
2012 Female, age 85, both hemispheres 741.8
2167 Male, age 76, both hemispheres 716.6
Reticulotegmental nucleus
nTPM: 675.7
2322 Female, age 91, both hemispheres 727.1
2333 Male, age 80, both hemispheres 704.0
2452 Male, age 74, both hemispheres 692.4
2325 Male, age 76, both hemispheres 579.1
Spinal trigeminal nucleus, oral
nTPM: 668.5
2164 Male, age 80, both hemispheres 709.4
1978 Male, age 76, both hemispheres 676.7
2737 Female, age 85, both hemispheres 619.3
Subcoeruleus area
nTPM: 706.5
2369 Female, age 85, left hemisphere 901.0
1958 Male, age 80, both hemispheres 692.6
2089 Male, age 76, left hemisphere 677.2
2451 Male, age 74, both hemispheres 637.3
2323 Female, age 91, left hemisphere 624.5
Superior olive
nTPM: 762.0
2020 Male, age 76, both hemispheres 862.2
2329 Male, age 80, right hemisphere 758.3
2364 Male, age 74, right hemisphere 752.4
2561 Female, age 91, both hemispheres 729.8
1875 Female, age 85, both hemispheres 707.1
Superior vestibular nucleus
nTPM: 668.2
2015 Male, age 80, both hemispheres 720.3
2383 Male, age 74, both hemispheres 649.8
2061 Male, age 76, both hemispheres 634.4
Ventral periolivary nuclei
nTPM: 718.4
2023 Male, age 76, both hemispheres 915.6
2165 Male, age 80, both hemispheres 684.5
2794 Female, age 91, left hemisphere 651.3
2130 Female, age 85, both hemispheres 622.1
Ventrolateral tegmental area, A5 NE cell group
nTPM: 746.3
2456 Female, age 91, both hemispheres 790.2
1959 Male, age 76, both hemispheres 772.8
2359 Male, age 61, both hemispheres 755.0
2840 Female, age 85, both hemispheres 749.9
2161 Male, age 80, both hemispheres 725.7
2449 Male, age 74, both hemispheres 684.3

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 505.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 397.3
FF:10165-103B3 76 years, female 460.5
FF:10182-103D2 60 years, female 334.1
Pons
Scaled Tags Per Million: 505.5
FF:10033-101E6 18-54 years, mixed 505.5

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 60.5
Pig sample Sample description nTPM
Pons
nTPM: 60.5
Samples: 4

Max nTPM: 86.2
Min nTPM: 40.0
Sample A Female 55.8
Sample B Female 40.0
Sample C Male 60.0
Sample D Male 86.2

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 12.7
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 12.7
45668 Antisense, RP_040324_01_H05, Mouse strain C57BL/6J (56 days, male) 12.7
67936386 Antisense, RP_040324_01_H05, Mouse strain C57BL/6J (56 days, male) 7.2

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by the Knut & Alice Wallenberg Foundation.