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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:328.2 nTPM
HPA:328.2 nTPM
GTEx:199.7 nTPM
FANTOM5:616.7 Scaled Tags Per Million
Pig:508.9 nTPM
Mouse:27.0 nTPM
Allen mouse:2.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 328.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 270.3
2019 Male, age 18, unknown 293.6
1870 Female, age 42, unknown 281.4
2666 Male, age 74, left hemisphere 278.6
2828 Female, age 72, unknown 274.8
1830 Male, age 51, unknown 274.4
1833 Male, age 53, unknown 273.8
2411 Female, age 72, unknown 262.3
1827 Male, age 72, unknown 259.9
2219 Male, age 76, both hemispheres 253.6
2586 Male, age 75, left hemisphere 250.7
Dorsal raphe nucleus
nTPM: 310.1
2016 Female, age 72, unknown 361.8
2298 Female, age 72, unknown 332.1
1828 Male, age 53, unknown 305.1
2047 Male, age 72, unknown 281.0
2750 Male, age 76, both hemispheres 270.3
Inferior colliculus
nTPM: 274.2
1890 Male, age 53, unknown 299.2
2097 Female, age 72, unknown 270.4
1848 Female, age 42, unknown 263.6
2849 Male, age 72, unknown 263.4
Median raphe nucleus
nTPM: 272.7
2220 Male, age 76, midline 272.7
Pedunculopontine tegmental nucleus
nTPM: 295.4
2338 Male, age 61, both hemispheres 360.6
2334 Male, age 80, both hemispheres 270.4
1921 Female, age 85, both hemispheres 255.1
Periaquaductal grey, anterior
nTPM: 297.8
1795 Male, age 51, unknown 332.7
2502 Female, age 75, unknown 286.0
1947 Male, age 18, unknown 274.6
Periaquaductal grey, dorsal
nTPM: 312.2
2850 Male, age 76, both hemispheres 375.9
1831 Male, age 72, unknown 326.6
1840 Male, age 53, unknown 274.2
2464 Female, age 72, unknown 271.9
Periaquaductal grey, lateral
nTPM: 328.2
2272 Male, age 74, both hemispheres 364.2
2140 Male, age 76, both hemispheres 329.1
2053 Male, age 18, unknown 291.4
Pretectal area
nTPM: 279.0
2273 Male, age 74, both hemispheres 352.0
2224 Female, age 72, unknown 292.5
2316 Male, age 76, right hemisphere 280.5
2825 Male, age 18, unknown 276.7
1817 Female, age 42, unknown 272.2
1815 Male, age 53, unknown 270.1
2667 Female, age 75, unknown 267.8
2407 Male, age 75, both hemispheres 267.0
2007 Male, age 72, unknown 263.9
1944 Female, age 72, unknown 263.6
1816 Male, age 51, unknown 263.2
Red nucleus
nTPM: 285.5
2785 Male, age 18, unknown 295.8
2725 Female, age 75, unknown 291.6
2769 Male, age 72, unknown 290.7
2227 Male, age 72, unknown 290.4
1821 Female, age 72, unknown 288.1
1904 Male, age 53, unknown 287.6
1954 Female, age 42, unknown 286.7
2584 Male, age 75, left hemisphere 286.1
1865 Male, age 51, unknown 284.8
2503 Female, age 72, unknown 278.0
2588 Male, age 74, left hemisphere 273.4
2823 Male, age 76, right hemisphere 272.7
Substantia nigra
nTPM: 281.1
2590 Female, age 75, unknown 302.9
2665 Male, age 74, both hemispheres 298.5
2699 Male, age 18, unknown 294.7
1851 Male, age 51, unknown 292.0
2583 Male, age 75, right hemisphere 282.0
2409 Female, age 72, unknown 272.8
1941 Male, age 53, unknown 270.7
1916 Female, age 42, unknown 267.8
2241 Male, age 72, unknown 265.4
1889 Female, age 72, unknown 264.6
Superior colliculus
nTPM: 289.1
1995 Male, age 72, unknown 370.9
1913 Female, age 42, unknown 319.6
2587 Male, age 74, left hemisphere 300.3
2087 Female, age 72, unknown 285.5
1796 Male, age 53, unknown 273.8
2668 Female, age 75, unknown 272.9
2261 Male, age 18, unknown 271.0
2664 Male, age 75, both hemispheres 269.9
1839 Male, age 51, unknown 266.8
1895 Male, age 76, right hemisphere 260.3
Ventral tegmental area
nTPM: 293.6
1915 Female, age 42, unknown 314.2
2223 Female, age 72, unknown 311.8
2021 Male, age 53, unknown 307.4
1942 Male, age 51, unknown 280.3
2218 Male, age 76, both hemispheres 276.5
2410 Female, age 72, unknown 271.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 199.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 199.7
Samples: 139

Max nTPM: 1131.4
Min nTPM: 59.3
Std nTPM: 147.2
Median nTPM: 162.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1131.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 797.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 745.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 734.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 592.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 510.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 392.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 378.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 349.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 341.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 334.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 332.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 328.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 326.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 325.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 325.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 322.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 320.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 319.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 316.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 314.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 299.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 298.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 296.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 291.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 282.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 275.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 269.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 268.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 263.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 254.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 248.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 247.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 244.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 243.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 240.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 240.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 223.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 220.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 220.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 215.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 213.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 205.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 204.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 203.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 199.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 197.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 192.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 192.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 188.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 188.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 186.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 185.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 185.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 184.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 184.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 183.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 180.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 174.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 174.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 173.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 170.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 170.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 169.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 167.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 164.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 164.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 163.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 163.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 162.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 162.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 160.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 159.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 158.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 153.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 150.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 148.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 148.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 148.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 148.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 144.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 143.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 143.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 138.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 138.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 137.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 134.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 134.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 133.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 132.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 130.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 125.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 125.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 124.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 124.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 124.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 123.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 122.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 122.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 121.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 121.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 119.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 118.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 116.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 114.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 113.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 112.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 112.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 108.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 106.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 106.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 105.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 104.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 102.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 102.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 101.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 101.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 99.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 95.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 93.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 92.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 91.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 90.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 89.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 89.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 87.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 85.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 84.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 79.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 75.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 74.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 73.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 71.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 65.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 65.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 63.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 60.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 59.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 59.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 616.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 616.7
FF:10158-103A5 76 years, female 616.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 508.9
Pig sample Sample description nTPM
Midbrain
nTPM: 92.3
Samples: 4

Max nTPM: 142.0
Min nTPM: 46.3
Sample A Female 142.0
Sample B Female 88.4
Sample C Male 92.3
Sample D Male 46.3
Periaqueductal gray
nTPM: 139.5
Samples: 3

Max nTPM: 169.5
Min nTPM: 117.9
Sample B Female 131.2
Sample C Male 169.5
Sample D Male 117.9
Substantia nigra
nTPM: 227.6
Samples: 4

Max nTPM: 568.9
Min nTPM: 66.2
Sample A Female 157.7
Sample B Female 568.9
Sample C Male 66.2
Sample D Male 117.5
Superior colliculi
nTPM: 508.9
Samples: 4

Max nTPM: 1287.7
Min nTPM: 88.3
Sample A Female 570.6
Sample B Female 1287.7
Sample C Male 88.3
Sample D Male 88.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 27.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 27.0
Samples: 4

Max nTPM: 33.6
Min nTPM: 23.5
Sample A Male 33.6
Sample B Male 25.4
Sample C Female 23.5
Sample D Female 25.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.5
79677371 Antisense, RP_071218_02_C05, Mouse strain C57BL/6J (56 days, male) 3.3
79677375 Antisense, RP_071218_02_C11, Mouse strain C57BL/6J (56 days, male) 2.9
1310 Antisense, RP_Baylor_103104, Mouse strain C57BL/6J (56 days, male) 1.3
79907904 Antisense, RP_071218_02_C05, Mouse strain C57BL/6J (56 days, male) 1.2
1309 Antisense, RP_Baylor_103104, Mouse strain C57BL/6J (56 days, male) 0.4

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