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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:490.6 nTPM
HPA:490.6 nTPM
GTEx:587.1 nTPM
FANTOM5:578.8 Scaled Tags Per Million
Pig:116.2 nTPM
Mouse:372.3 nTPM
Allen mouse:6.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 490.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 468.2
2666 Male, age 74, left hemisphere 569.6
2586 Male, age 75, left hemisphere 558.1
2019 Male, age 18, unknown 548.7
2828 Female, age 72, unknown 475.3
1827 Male, age 72, unknown 456.2
1833 Male, age 53, unknown 436.6
1830 Male, age 51, unknown 432.6
2411 Female, age 72, unknown 428.4
1870 Female, age 42, unknown 408.2
2219 Male, age 76, both hemispheres 368.8
Dorsal raphe nucleus
nTPM: 391.8
2750 Male, age 76, both hemispheres 441.1
1828 Male, age 53, unknown 403.0
2016 Female, age 72, unknown 387.8
2047 Male, age 72, unknown 375.3
2298 Female, age 72, unknown 351.9
Inferior colliculus
nTPM: 370.0
1890 Male, age 53, unknown 394.9
1848 Female, age 42, unknown 375.0
2849 Male, age 72, unknown 369.7
2097 Female, age 72, unknown 340.2
Median raphe nucleus
nTPM: 413.1
2220 Male, age 76, midline 413.1
Pedunculopontine tegmental nucleus
nTPM: 410.3
2334 Male, age 80, both hemispheres 429.3
2338 Male, age 61, both hemispheres 425.6
1921 Female, age 85, both hemispheres 375.9
Periaquaductal grey, anterior
nTPM: 406.3
2502 Female, age 75, unknown 432.7
1795 Male, age 51, unknown 402.4
1947 Male, age 18, unknown 383.9
Periaquaductal grey, dorsal
nTPM: 377.4
2850 Male, age 76, both hemispheres 399.3
1831 Male, age 72, unknown 390.9
2464 Female, age 72, unknown 386.0
1840 Male, age 53, unknown 333.3
Periaquaductal grey, lateral
nTPM: 371.9
2140 Male, age 76, both hemispheres 378.8
2053 Male, age 18, unknown 376.9
2272 Male, age 74, both hemispheres 359.9
Pretectal area
nTPM: 447.3
2007 Male, age 72, unknown 557.3
1815 Male, age 53, unknown 549.9
1816 Male, age 51, unknown 547.4
1817 Female, age 42, unknown 515.3
1944 Female, age 72, unknown 514.7
2407 Male, age 75, both hemispheres 421.5
2316 Male, age 76, right hemisphere 381.7
2825 Male, age 18, unknown 374.4
2667 Female, age 75, unknown 370.2
2224 Female, age 72, unknown 346.8
2273 Male, age 74, both hemispheres 341.3
Red nucleus
nTPM: 490.6
2588 Male, age 74, left hemisphere 622.4
2785 Male, age 18, unknown 544.3
2503 Female, age 72, unknown 530.0
2584 Male, age 75, left hemisphere 500.4
1865 Male, age 51, unknown 486.0
1904 Male, age 53, unknown 485.5
2725 Female, age 75, unknown 478.6
1821 Female, age 72, unknown 464.9
2823 Male, age 76, right hemisphere 447.5
1954 Female, age 42, unknown 444.6
2769 Male, age 72, unknown 441.6
2227 Male, age 72, unknown 440.9
Substantia nigra
nTPM: 444.9
2665 Male, age 74, both hemispheres 502.5
1889 Female, age 72, unknown 478.7
2583 Male, age 75, right hemisphere 466.3
2590 Female, age 75, unknown 459.4
1916 Female, age 42, unknown 449.2
1851 Male, age 51, unknown 445.7
2241 Male, age 72, unknown 417.7
1941 Male, age 53, unknown 415.7
2699 Male, age 18, unknown 411.0
2409 Female, age 72, unknown 402.8
Superior colliculus
nTPM: 444.3
2668 Female, age 75, unknown 482.8
2587 Male, age 74, left hemisphere 471.2
2664 Male, age 75, both hemispheres 467.0
2087 Female, age 72, unknown 466.1
1995 Male, age 72, unknown 454.5
2261 Male, age 18, unknown 447.8
1913 Female, age 42, unknown 442.6
1796 Male, age 53, unknown 430.0
1839 Male, age 51, unknown 409.4
1895 Male, age 76, right hemisphere 372.0
Ventral tegmental area
nTPM: 413.4
2410 Female, age 72, unknown 446.0
2223 Female, age 72, unknown 429.4
2218 Male, age 76, both hemispheres 420.6
1915 Female, age 42, unknown 402.0
2021 Male, age 53, unknown 396.5
1942 Male, age 51, unknown 386.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 587.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 587.1
Samples: 139

Max nTPM: 1377.0
Min nTPM: 233.1
Std nTPM: 253.3
Median nTPM: 512.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1377.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1298.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1263.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1217.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1179.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1161.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1156.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1136.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1130.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1091.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1047.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1034.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1025.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 981.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 968.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 960.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 952.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 942.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 923.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 901.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 901.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 875.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 855.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 842.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 830.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 825.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 779.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 773.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 765.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 754.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 737.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 729.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 712.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 707.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 707.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 700.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 694.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 679.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 669.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 664.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 661.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 649.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 646.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 641.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 638.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 637.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 634.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 630.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 629.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 623.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 593.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 590.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 579.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 572.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 562.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 558.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 551.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 548.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 545.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 541.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 537.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 530.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 530.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 525.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 525.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 522.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 521.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 520.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 517.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 512.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 511.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 507.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 497.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 492.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 488.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 488.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 487.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 481.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 480.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 475.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 473.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 470.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 462.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 462.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 451.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 446.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 446.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 442.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 441.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 439.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 437.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 432.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 427.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 422.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 420.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 417.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 416.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 412.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 409.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 406.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 404.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 404.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 403.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 402.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 398.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 396.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 394.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 393.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 393.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 386.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 386.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 383.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 382.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 380.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 376.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 375.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 374.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 373.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 366.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 366.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 365.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 361.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 358.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 355.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 336.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 331.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 326.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 325.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 315.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 312.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 311.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 310.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 308.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 305.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 300.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 293.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 272.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 255.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 233.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 578.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 578.8
FF:10158-103A5 76 years, female 578.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 116.2
Pig sample Sample description nTPM
Midbrain
nTPM: 116.3
Samples: 4

Max nTPM: 166.8
Min nTPM: 72.4
Sample A Female 153.1
Sample B Female 72.4
Sample C Male 166.8
Sample D Male 72.7
Periaqueductal gray
nTPM: 66.1
Samples: 3

Max nTPM: 67.4
Min nTPM: 63.9
Sample B Female 67.4
Sample C Male 67.0
Sample D Male 63.9
Substantia nigra
nTPM: 88.6
Samples: 4

Max nTPM: 102.0
Min nTPM: 81.8
Sample A Female 87.9
Sample B Female 82.7
Sample C Male 81.8
Sample D Male 102.0
Superior colliculi
nTPM: 106.2
Samples: 4

Max nTPM: 142.5
Min nTPM: 80.3
Sample A Female 95.4
Sample B Female 80.3
Sample C Male 142.5
Sample D Male 106.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 372.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 372.3
Samples: 4

Max nTPM: 377.3
Min nTPM: 369.1
Sample A Male 372.3
Sample B Male 377.3
Sample C Female 370.4
Sample D Female 369.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.5
71587919 Antisense, RP_050725_03_G05, Mouse strain C57BL/6J (56 days, male) 6.5
68845598 Antisense, RP_050224_02_B05, Mouse strain C57BL/6J (56 days, male) 6.5

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