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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:154.4 nTPM
HPA:154.4 nTPM
GTEx:160.5 nTPM
FANTOM5:110.1 Scaled Tags Per Million
Pig:264.0 nTPM
Mouse:461.6 nTPM
Allen mouse:10.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 154.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 141.6
2411 Female, age 72, unknown 150.5
2586 Male, age 75, left hemisphere 149.5
1827 Male, age 72, unknown 146.4
1870 Female, age 42, unknown 145.5
2019 Male, age 18, unknown 144.8
1833 Male, age 53, unknown 140.4
1830 Male, age 51, unknown 140.2
2219 Male, age 76, both hemispheres 138.0
2828 Female, age 72, unknown 131.3
2666 Male, age 74, left hemisphere 129.6
Dorsal raphe nucleus
nTPM: 144.8
2298 Female, age 72, unknown 150.1
1828 Male, age 53, unknown 148.8
2047 Male, age 72, unknown 144.6
2016 Female, age 72, unknown 142.1
2750 Male, age 76, both hemispheres 138.6
Inferior colliculus
nTPM: 146.9
2097 Female, age 72, unknown 150.5
1848 Female, age 42, unknown 149.4
2849 Male, age 72, unknown 147.3
1890 Male, age 53, unknown 140.6
Median raphe nucleus
nTPM: 145.4
2220 Male, age 76, midline 145.4
Pedunculopontine tegmental nucleus
nTPM: 146.5
1921 Female, age 85, both hemispheres 153.6
2334 Male, age 80, both hemispheres 152.2
2338 Male, age 61, both hemispheres 133.8
Periaquaductal grey, anterior
nTPM: 146.9
1947 Male, age 18, unknown 154.0
1795 Male, age 51, unknown 143.7
2502 Female, age 75, unknown 143.1
Periaquaductal grey, dorsal
nTPM: 147.7
1840 Male, age 53, unknown 158.7
2850 Male, age 76, both hemispheres 154.1
1831 Male, age 72, unknown 141.7
2464 Female, age 72, unknown 136.4
Periaquaductal grey, lateral
nTPM: 146.6
2272 Male, age 74, both hemispheres 158.2
2140 Male, age 76, both hemispheres 142.8
2053 Male, age 18, unknown 138.8
Pretectal area
nTPM: 149.8
2273 Male, age 74, both hemispheres 167.0
2224 Female, age 72, unknown 156.7
1816 Male, age 51, unknown 153.3
2407 Male, age 75, both hemispheres 151.9
1817 Female, age 42, unknown 151.5
2007 Male, age 72, unknown 151.1
1944 Female, age 72, unknown 149.5
2825 Male, age 18, unknown 146.1
1815 Male, age 53, unknown 143.8
2667 Female, age 75, unknown 143.8
2316 Male, age 76, right hemisphere 133.3
Red nucleus
nTPM: 131.2
2725 Female, age 75, unknown 147.2
1821 Female, age 72, unknown 140.8
2584 Male, age 75, left hemisphere 136.2
2785 Male, age 18, unknown 135.6
1954 Female, age 42, unknown 131.4
2227 Male, age 72, unknown 129.9
2769 Male, age 72, unknown 127.6
1865 Male, age 51, unknown 127.0
2503 Female, age 72, unknown 126.3
1904 Male, age 53, unknown 124.9
2588 Male, age 74, left hemisphere 124.2
2823 Male, age 76, right hemisphere 123.3
Substantia nigra
nTPM: 154.4
2241 Male, age 72, unknown 170.4
1916 Female, age 42, unknown 165.3
1941 Male, age 53, unknown 163.1
1851 Male, age 51, unknown 162.2
2583 Male, age 75, right hemisphere 155.2
1889 Female, age 72, unknown 152.6
2699 Male, age 18, unknown 151.1
2409 Female, age 72, unknown 148.8
2590 Female, age 75, unknown 143.8
2665 Male, age 74, both hemispheres 131.8
Superior colliculus
nTPM: 143.8
2664 Male, age 75, both hemispheres 165.0
2587 Male, age 74, left hemisphere 148.4
1796 Male, age 53, unknown 147.7
1839 Male, age 51, unknown 146.5
2668 Female, age 75, unknown 143.7
2087 Female, age 72, unknown 141.4
2261 Male, age 18, unknown 140.4
1895 Male, age 76, right hemisphere 138.1
1995 Male, age 72, unknown 134.1
1913 Female, age 42, unknown 132.3
Ventral tegmental area
nTPM: 151.7
2223 Female, age 72, unknown 158.4
1915 Female, age 42, unknown 157.8
2410 Female, age 72, unknown 152.9
2218 Male, age 76, both hemispheres 149.8
1942 Male, age 51, unknown 146.2
2021 Male, age 53, unknown 145.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 160.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 160.5
Samples: 139

Max nTPM: 330.0
Min nTPM: 85.4
Std nTPM: 39.9
Median nTPM: 158.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 330.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 275.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 270.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 269.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 266.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 259.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 240.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 232.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 230.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 226.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 215.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 212.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 209.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 208.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 207.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 207.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 203.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 200.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 200.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 198.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 198.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 195.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 195.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 193.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 192.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 186.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 186.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 178.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 178.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 177.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 176.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 176.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 175.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 175.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 175.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 174.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 174.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 172.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 172.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 172.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 171.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 170.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 170.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 169.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 169.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 169.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 167.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 167.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 167.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 167.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 166.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 166.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 165.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 165.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 165.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 164.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 164.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 163.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 163.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 162.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 162.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 162.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 162.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 162.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 161.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 161.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 159.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 159.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 158.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 158.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 158.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 157.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 157.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 155.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 154.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 154.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 154.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 154.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 154.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 153.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 153.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 152.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 150.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 149.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 148.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 147.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 147.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 146.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 146.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 146.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 145.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 144.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 143.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 143.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 143.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 142.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 141.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 141.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 140.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 140.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 139.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 135.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 135.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 133.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 133.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 132.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 131.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 130.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 129.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 129.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 129.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 125.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 125.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 124.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 124.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 122.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 122.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 121.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 120.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 118.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 118.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 118.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 116.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 116.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 116.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 114.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 112.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 110.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 109.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 109.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 108.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 107.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 104.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 100.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 100.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 98.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 98.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 93.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 85.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 110.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 110.1
FF:10158-103A5 76 years, female 110.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 264.0
Pig sample Sample description nTPM
Midbrain
nTPM: 258.4
Samples: 4

Max nTPM: 276.2
Min nTPM: 232.1
Sample A Female 262.9
Sample B Female 232.1
Sample C Male 276.2
Sample D Male 262.3
Periaqueductal gray
nTPM: 217.7
Samples: 3

Max nTPM: 254.7
Min nTPM: 198.5
Sample B Female 198.5
Sample C Male 254.7
Sample D Male 199.9
Substantia nigra
nTPM: 227.5
Samples: 4

Max nTPM: 327.2
Min nTPM: 132.9
Sample A Female 327.2
Sample B Female 195.2
Sample C Male 254.5
Sample D Male 132.9
Superior colliculi
nTPM: 264.0
Samples: 4

Max nTPM: 300.8
Min nTPM: 214.5
Sample A Female 300.8
Sample B Female 214.5
Sample C Male 288.2
Sample D Male 252.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 461.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 461.6
Samples: 4

Max nTPM: 474.0
Min nTPM: 451.8
Sample A Male 460.1
Sample B Male 474.0
Sample C Female 451.8
Sample D Female 460.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.0
1262 Antisense, RP_040324_01_F06, Mouse strain C57BL/6J (56 days, male) 10.0
1261 Antisense, RP_040324_01_F06, Mouse strain C57BL/6J (56 days, male) 9.0

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