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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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131.347
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:104.2 nTPM
HPA:104.2 nTPM
FANTOM5:383.9 Scaled Tags Per Million
Pig:130.1 nTPM
Mouse:262.5 nTPM
Allen mouse:15.3 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA035876
Pons mean intensity 131.347
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

Read more
FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 38.825
Parabrachial nucleus 44.905
Principle sensory trigeminal nucleus 60.359
Locus coeruleus 131.347
Pontine nucleus 67.227
Vestibular nucleus 12.455
Pontine reticular nucleus, oral 38.514
Lateral lemniscus 59.405
Superior paraolivary nucleus 18.746

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 104.2
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 2.8
2301 Female, age 85, both hemispheres 6.3
1984 Male, age 76, both hemispheres 5.2
2090 Male, age 80, both hemispheres 0.0
2188 Female, age 91, both hemispheres 0.0
Area postrema
nTPM: 0.0
2054 Male, age 76, both hemispheres 0.0
2306 Male, age 80, both hemispheres 0.0
2799 Male, age 61, both hemispheres 0.0
Cuneate nuclei
nTPM: 3.0
2131 Male, age 76, both hemispheres 9.1
2376 Male, age 61, both hemispheres 0.0
2381 Male, age 80, both hemispheres 0.0
Dorsal cochlear nucleus
nTPM: 0.0
2058 Male, age 76, both hemispheres 0.0
2187 Female, age 91, both hemispheres 0.0
2370 Male, age 61, both hemispheres 0.0
2378 Male, age 80, both hemispheres 0.0
2802 Male, age 74, right hemisphere 0.0
Dorsal medullary reticular nucleus
nTPM: 12.2
2040 Female, age 85, both hemispheres 36.8
2088 Male, age 76, both hemispheres 0.0
2373 Male, age 61, both hemispheres 0.0
Dorsal motor vagal complex
nTPM: 1.4
2133 Female, age 91, both hemispheres 11.7
2000 Male, age 74, unknown 0.0
2185 Male, age 76, both hemispheres 0.0
2643 Male, age 74, both hemispheres 0.0
2797 Male, age 61, both hemispheres 0.0
2807 Female, age 85, both hemispheres 0.0
2813 Female, age 72, unknown 0.0
2844 Male, age 55, unknown 0.0
Dorsal tegmental nucleus
nTPM: 0.0
2083 Male, age 80, both hemispheres 0.1
1936 Male, age 76, left hemisphere 0.0
2326 Male, age 74, both hemispheres 0.0
2358 Male, age 61, both hemispheres 0.0
Dorsolateral tegmental area
nTPM: 1.2
2141 Male, age 76, both hemispheres 6.3
2337 Male, age 61, both hemispheres 0.0
2360 Male, age 74, both hemispheres 0.0
2654 Male, age 80, both hemispheres 0.0
2751 Female, age 85, both hemispheres 0.0
Gigantocellular reticular nuclei, medullary
nTPM: 27.2
2462 Male, age 74, both hemispheres 126.4
2310 Male, age 80, both hemispheres 32.0
2022 Male, age 76, right hemisphere 3.8
1876 Female, age 85, both hemispheres 1.0
2314 Male, age 61, both hemispheres 0.0
2387 Female, age 91, both hemispheres 0.0
Gigantocellular reticular nuclei, pars
nTPM: 36.9
2168 Male, age 76, both hemispheres 91.3
2084 Female, age 85, both hemispheres 25.7
2706 Male, age 80, both hemispheres 23.7
2330 Male, age 80, both hemispheres 22.2
2336 Male, age 61, both hemispheres 21.5
Inferior olive
nTPM: 0.0
2085 Female, age 85, both hemispheres 0.0
2178 Male, age 61, both hemispheres 0.0
2379 Male, age 80, both hemispheres 0.0
2563 Male, age 74, both hemispheres 0.0
2628 Female, age 91, both hemispheres 0.0
Kolliker-Fuse nucleus
nTPM: 10.3
2793 Female, age 91, left hemisphere 29.3
2163 Male, age 80, both hemispheres 1.6
2315 Male, age 76, right hemisphere 0.0
Lateral lemniscal nuclei
nTPM: 64.4
2453 Male, age 74, right hemisphere 104.6
2169 Male, age 76, both hemispheres 91.3
2036 Male, age 80, both hemispheres 60.0
2746 Female, age 85, left hemisphere 47.0
2320 Female, age 91, left hemisphere 19.1
Lateral medullary reticular nucleus
nTPM: 6.0
2044 Male, age 76, both hemispheres 36.1
2190 Female, age 85, both hemispheres 0.0
2305 Male, age 74, both hemispheres 0.0
2374 Male, age 61, both hemispheres 0.0
2804 Female, age 91, both hemispheres 0.0
2852 Male, age 80, both hemispheres 0.0
Lateral parabrachial nucleus
nTPM: 18.3
2139 Female, age 85, right hemisphere 67.0
2790 Male, age 61, both hemispheres 6.3
2013 Male, age 80, both hemispheres 0.0
2792 Male, age 76, both hemispheres 0.0
Lateral vestibular nucleus
nTPM: 0.0
2184 Male, age 76, both hemispheres 0.0
2311 Male, age 80, both hemispheres 0.0
Locus coeruleus
nTPM: 22.5
2720 Male, age 74, both hemispheres 71.1
2123 Female, age 91, both hemispheres 64.3
2162 Male, age 80, both hemispheres 16.7
1980 Male, age 76, both hemispheres 5.5
2014 Male, age 55, unknown 0.0
2317 Female, age 72, unknown 0.0
2788 Male, age 74, unknown 0.0
Medial olivary nucleus
nTPM: 0.0
1943 Male, age 61, both hemispheres 0.0
1962 Male, age 76, both hemispheres 0.0
2138 Female, age 91, both hemispheres 0.0
2851 Male, age 80, both hemispheres 0.0
Medial parabrachial nucleus
nTPM: 10.0
2854 Male, age 80, both hemispheres 34.4
2156 Male, age 61, both hemispheres 15.8
2170 Female, age 91, both hemispheres 0.0
2463 Female, age 85, right hemisphere 0.0
2786 Male, age 76, both hemispheres 0.0
Medial periolivary nuclei
nTPM: 50.6
2171 Female, age 85, both hemispheres 150.2
2063 Male, age 76, both hemispheres 73.0
2791 Male, age 74, right hemisphere 25.6
2458 Female, age 91, both hemispheres 4.1
2081 Male, age 80, both hemispheres 0.0
Medial vestibular nucleus
nTPM: 23.5
2624 Male, age 61, both hemispheres 51.8
2803 Female, age 91, both hemispheres 35.8
2801 Male, age 74, both hemispheres 20.7
2093 Male, age 80, both hemispheres 19.1
2743 Female, age 85, both hemispheres 13.3
2134 Male, age 76, both hemispheres 0.0
Motor facial nucleus
nTPM: 59.6
2327 Male, age 80, both hemispheres 90.2
2062 Male, age 76, both hemispheres 87.5
2365 Male, age 74, right hemisphere 87.2
2697 Female, age 85, both hemispheres 78.0
2795 Female, age 91, both hemispheres 14.4
2126 Male, age 61, both hemispheres 0.0
Motor hypoglossal nucleus
nTPM: 11.5
2125 Female, age 91, both hemispheres 24.3
2132 Female, age 85, both hemispheres 21.7
2461 Male, age 61, both hemispheres 11.7
2182 Male, age 80, both hemispheres 0.0
2277 Male, age 76, both hemispheres 0.0
Motor trigeminal nucleus
nTPM: 22.5
2079 Male, age 80, both hemispheres 54.4
2560 Male, age 74, both hemispheres 39.0
2335 Male, age 61, both hemispheres 19.3
2309 Male, age 76, both hemispheres 0.0
2321 Female, age 91, both hemispheres 0.0
Nuclei of the trapezoid body
nTPM: 77.7
2159 Male, age 61, both hemispheres 145.3
2735 Female, age 85, both hemispheres 114.7
1983 Male, age 76, both hemispheres 78.7
2166 Male, age 80, both hemispheres 38.5
2368 Female, age 91, both hemispheres 11.0
Nucleus ambiguus
nTPM: 36.0
2096 Female, age 85, both hemispheres 72.1
2071 Male, age 76, both hemispheres 0.0
Nucleus cuneatus
nTPM: 1.5
2562 Male, age 61, both hemispheres 9.3
2100 Male, age 76, both hemispheres 0.0
2380 Male, age 80, both hemispheres 0.0
2564 Male, age 74, both hemispheres 0.0
2805 Female, age 91, both hemispheres 0.0
2808 Female, age 85, both hemispheres 0.0
Nucleus gracilis
nTPM: 0.0
2299 Female, age 85, both hemispheres 0.0
2382 Male, age 80, both hemispheres 0.0
2627 Male, age 74, both hemispheres 0.0
Nucleus raphe magnus
nTPM: 104.2
2172 Female, age 85, both hemispheres 182.6
2160 Male, age 61, both hemispheres 164.3
2455 Male, age 74, both hemispheres 144.1
2328 Male, age 80, both hemispheres 70.4
2051 Male, age 76, both hemispheres 49.0
2459 Female, age 91, both hemispheres 14.8
Nucleus raphe obscurus
nTPM: 0.0
2142 Male, age 76, midline 0.0
2800 Male, age 61, midline 0.0
2845 Female, age 85, midline 0.0
Nucleus raphe pallidus
nTPM: 0.0
1924 Male, age 61, midline 0.0
2145 Male, age 76, midline 0.0
2183 Male, age 80, midline 0.0
Nucleus tractus solitarii
nTPM: 0.0
2144 Female, age 91, right hemisphere 0.0
2191 Female, age 85, both hemispheres 0.0
2307 Male, age 80, both hemispheres 0.0
2656 Male, age 76, both hemispheres 0.0
Paramedian reticular nucleus
nTPM: 28.6
2050 Female, age 85, both hemispheres 70.7
2313 Male, age 61, both hemispheres 38.9
2057 Male, age 80, both hemispheres 4.7
2052 Male, age 76, both hemispheres 0.0
Parvicellular reticular nuclei
nTPM: 35.5
2558 Male, age 74, both hemispheres 104.6
2095 Male, age 76, both hemispheres 1.9
2119 Male, age 80, both hemispheres 0.0
Parvicellular reticular nuclei, medullary
nTPM: 18.1
2189 Female, age 91, both hemispheres 28.9
2181 Male, age 80, left hemisphere 25.4
2091 Female, age 85, both hemispheres 0.0
Peritrigeminal nucleus
nTPM: 10.9
2179 Male, age 61, both hemispheres 32.1
2136 Male, age 76, both hemispheres 0.5
2067 Female, age 85, both hemispheres 0.0
Pontine nuclei
nTPM: 60.4
2787 Female, age 85, both hemispheres 174.5
1863 Male, age 55, unknown 84.4
2727 Male, age 61, right hemisphere 76.0
1968 Male, age 76, left hemisphere 73.6
2109 Female, age 72, unknown 40.1
2454 Male, age 74, left hemisphere 23.7
2115 Male, age 80, left hemisphere 10.7
2319 Female, age 91, both hemispheres 0.0
Pontine raphe nucleus
nTPM: 33.8
2122 Female, age 85, midline 55.7
2853 Male, age 76, midline 11.8
Posteroventral cochlear nucleus
nTPM: 6.1
2752 Female, age 85, both hemispheres 30.6
2070 Male, age 76, both hemispheres 0.0
2135 Female, age 91, both hemispheres 0.0
2341 Male, age 80, both hemispheres 0.0
2371 Male, age 61, both hemispheres 0.0
Prepositus hypoglossal nucleus
nTPM: 4.0
2855 Female, age 85, right hemisphere 8.1
2086 Male, age 80, both hemispheres 0.0
Principal sensory trigeminal nucleus
nTPM: 49.7
2158 Male, age 61, both hemispheres 127.6
2008 Male, age 80, left hemisphere 64.1
2367 Female, age 91, left hemisphere 7.2
2324 Male, age 76, both hemispheres 0.0
Reticular pontine nucleus, caudal
nTPM: 32.9
2332 Male, age 80, right hemisphere 96.3
2092 Male, age 76, both hemispheres 30.7
2457 Female, age 91, both hemispheres 4.7
2559 Male, age 74, both hemispheres 0.0
Reticular pontine nucleus, oral
nTPM: 15.6
2361 Male, age 74, both hemispheres 51.3
2012 Female, age 85, both hemispheres 26.6
2366 Female, age 91, both hemispheres 0.1
1939 Male, age 80, both hemispheres 0.0
2167 Male, age 76, both hemispheres 0.0
Reticulotegmental nucleus
nTPM: 14.6
2325 Male, age 76, both hemispheres 38.6
2333 Male, age 80, both hemispheres 10.3
2452 Male, age 74, both hemispheres 6.9
2322 Female, age 91, both hemispheres 2.8
Spinal trigeminal nucleus, caudal
nTPM: 8.6
2390 Female, age 91, both hemispheres 32.5
2447 Male, age 76, both hemispheres 10.4
2308 Male, age 80, both hemispheres 0.0
2312 Male, age 61, both hemispheres 0.0
2642 Male, age 74, both hemispheres 0.0
Spinal trigeminal nucleus, interpolar
nTPM: 35.4
2389 Female, age 91, both hemispheres 63.5
2066 Male, age 76, right hemisphere 58.3
2625 Male, age 61, both hemispheres 31.7
2033 Male, age 80, both hemispheres 14.5
2386 Female, age 85, both hemispheres 9.0
Spinal trigeminal nucleus, oral
nTPM: 8.2
2737 Female, age 85, both hemispheres 13.3
1978 Male, age 76, both hemispheres 10.5
2164 Male, age 80, both hemispheres 0.7
Spinal vestibular nucleus
nTPM: 18.7
2186 Female, age 91, both hemispheres 42.2
2796 Male, age 61, both hemispheres 41.4
2780 Male, age 80, both hemispheres 15.6
2806 Female, age 85, both hemispheres 13.3
2384 Male, age 74, both hemispheres 0.0
2748 Male, age 76, both hemispheres 0.0
Subcoeruleus area
nTPM: 24.0
2323 Female, age 91, left hemisphere 50.9
1958 Male, age 80, both hemispheres 36.6
2089 Male, age 76, left hemisphere 32.7
2369 Female, age 85, left hemisphere 0.0
2451 Male, age 74, both hemispheres 0.0
Superior olive
nTPM: 47.2
1875 Female, age 85, both hemispheres 91.7
2329 Male, age 80, right hemisphere 51.2
2561 Female, age 91, both hemispheres 41.8
2364 Male, age 74, right hemisphere 32.7
2020 Male, age 76, both hemispheres 18.5
Superior vestibular nucleus
nTPM: 0.0
2015 Male, age 80, both hemispheres 0.0
2061 Male, age 76, both hemispheres 0.0
2383 Male, age 74, both hemispheres 0.0
Ventral medullary reticular nucleus
nTPM: 0.0
2060 Male, age 76, both hemispheres 0.0
2372 Male, age 61, both hemispheres 0.0
Ventral periolivary nuclei
nTPM: 69.4
2130 Female, age 85, both hemispheres 115.5
2165 Male, age 80, both hemispheres 107.9
2794 Female, age 91, left hemisphere 52.9
2023 Male, age 76, both hemispheres 1.3
Ventrolateral medulla, A1-C1 cell groups
nTPM: 5.3
2741 Female, age 85, both hemispheres 18.2
1986 Male, age 76, both hemispheres 8.3
2118 Male, age 80, both hemispheres 0.0
2180 Male, age 61, both hemispheres 0.0
2302 Female, age 91, both hemispheres 0.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 38.1
2449 Male, age 74, both hemispheres 106.8
1959 Male, age 76, both hemispheres 43.3
2840 Female, age 85, both hemispheres 43.3
2161 Male, age 80, both hemispheres 35.1
2359 Male, age 61, both hemispheres 0.0
2456 Female, age 91, both hemispheres 0.0

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 383.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 127.7
FF:10182-103D2 60 years, female 162.1
FF:10165-103B3 76 years, female 93.3
Medulla oblongata
Scaled Tags Per Million: 79.8
FF:10038-101F2 18-64 years, mixed 129.3
FF:10155-103A2 76 years, female 73.3
FF:10174-103C3 60 years, female 36.8
Pons
Scaled Tags Per Million: 383.9
FF:10033-101E6 18-54 years, mixed 383.9

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 130.1
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 67.9
Samples: 4

Max nTPM: 87.9
Min nTPM: 27.1
Sample A Female 76.5
Sample B Female 87.9
Sample C Male 80.0
Sample D Male 27.1
Pons
nTPM: 130.1
Samples: 4

Max nTPM: 185.0
Min nTPM: 72.8
Sample A Female 185.0
Sample B Female 72.8
Sample C Male 77.6
Sample D Male 184.9

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 262.5
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 262.6
Samples: 4

Max nTPM: 281.9
Min nTPM: 237.1
Sample A Male 281.9
Sample B Male 257.3
Sample C Female 273.9
Sample D Female 237.1

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.3
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 15.3
100144408 Antisense, RP_110407_01_G07, Mouse strain C57BL/6J (56 days, male) 15.3
Pons
Expression energy: 14.6
100144408 Antisense, RP_110407_01_G07, Mouse strain C57BL/6J (56 days, male) 14.6

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