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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:617.7 nTPM
HPA:617.7 nTPM
GTEx:650.8 nTPM
FANTOM5:286.1 Scaled Tags Per Million
Pig:232.3 nTPM
Mouse:427.4 nTPM
Allen mouse:7.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 617.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 609.1
2586 Male, age 75, left hemisphere 665.5
2411 Female, age 72, unknown 622.6
2666 Male, age 74, left hemisphere 619.8
1870 Female, age 42, unknown 610.4
1827 Male, age 72, unknown 603.7
2828 Female, age 72, unknown 603.3
1833 Male, age 53, unknown 597.4
1830 Male, age 51, unknown 593.3
2019 Male, age 18, unknown 589.2
2219 Male, age 76, both hemispheres 585.8
Dorsal raphe nucleus
nTPM: 609.4
2298 Female, age 72, unknown 614.0
2016 Female, age 72, unknown 611.4
2750 Male, age 76, both hemispheres 610.5
2047 Male, age 72, unknown 607.4
1828 Male, age 53, unknown 603.5
Inferior colliculus
nTPM: 593.9
1890 Male, age 53, unknown 601.7
2097 Female, age 72, unknown 597.4
1848 Female, age 42, unknown 592.1
2849 Male, age 72, unknown 584.5
Median raphe nucleus
nTPM: 588.8
2220 Male, age 76, midline 588.8
Pedunculopontine tegmental nucleus
nTPM: 595.0
2334 Male, age 80, both hemispheres 608.9
2338 Male, age 61, both hemispheres 590.6
1921 Female, age 85, both hemispheres 585.5
Periaquaductal grey, anterior
nTPM: 617.7
2502 Female, age 75, unknown 641.7
1947 Male, age 18, unknown 607.6
1795 Male, age 51, unknown 604.0
Periaquaductal grey, dorsal
nTPM: 592.9
1840 Male, age 53, unknown 603.2
2464 Female, age 72, unknown 599.8
1831 Male, age 72, unknown 598.5
2850 Male, age 76, both hemispheres 570.3
Periaquaductal grey, lateral
nTPM: 584.2
2053 Male, age 18, unknown 608.9
2140 Male, age 76, both hemispheres 573.1
2272 Male, age 74, both hemispheres 570.6
Pretectal area
nTPM: 589.3
2825 Male, age 18, unknown 599.7
2407 Male, age 75, both hemispheres 598.4
2316 Male, age 76, right hemisphere 597.0
2007 Male, age 72, unknown 596.3
1815 Male, age 53, unknown 592.8
2224 Female, age 72, unknown 591.6
1817 Female, age 42, unknown 591.3
1816 Male, age 51, unknown 588.8
2273 Male, age 74, both hemispheres 576.2
1944 Female, age 72, unknown 575.6
2667 Female, age 75, unknown 574.5
Red nucleus
nTPM: 614.9
2503 Female, age 72, unknown 642.2
2584 Male, age 75, left hemisphere 631.2
1821 Female, age 72, unknown 625.0
2769 Male, age 72, unknown 622.4
1904 Male, age 53, unknown 622.0
2588 Male, age 74, left hemisphere 620.9
2227 Male, age 72, unknown 619.3
1865 Male, age 51, unknown 618.1
2785 Male, age 18, unknown 602.5
2725 Female, age 75, unknown 601.0
1954 Female, age 42, unknown 593.8
2823 Male, age 76, right hemisphere 580.4
Substantia nigra
nTPM: 612.6
1851 Male, age 51, unknown 642.6
2665 Male, age 74, both hemispheres 626.2
2699 Male, age 18, unknown 624.5
2590 Female, age 75, unknown 623.8
1916 Female, age 42, unknown 613.4
2583 Male, age 75, right hemisphere 610.9
1889 Female, age 72, unknown 602.9
1941 Male, age 53, unknown 595.7
2241 Male, age 72, unknown 593.3
2409 Female, age 72, unknown 592.7
Superior colliculus
nTPM: 607.6
2664 Male, age 75, both hemispheres 636.1
2587 Male, age 74, left hemisphere 627.2
1995 Male, age 72, unknown 613.9
1839 Male, age 51, unknown 608.0
1796 Male, age 53, unknown 607.5
1913 Female, age 42, unknown 606.8
2668 Female, age 75, unknown 605.3
2261 Male, age 18, unknown 594.3
1895 Male, age 76, right hemisphere 590.3
2087 Female, age 72, unknown 586.3
Ventral tegmental area
nTPM: 611.2
2410 Female, age 72, unknown 628.6
1915 Female, age 42, unknown 624.1
2223 Female, age 72, unknown 613.5
2021 Male, age 53, unknown 609.3
1942 Male, age 51, unknown 605.8
2218 Male, age 76, both hemispheres 585.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 650.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 650.8
Samples: 139

Max nTPM: 1896.7
Min nTPM: 299.7
Std nTPM: 238.9
Median nTPM: 601.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1896.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1434.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1326.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1324.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1230.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1174.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1130.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1105.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1087.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1071.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 966.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 958.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 956.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 939.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 936.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 925.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 904.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 899.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 887.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 872.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 861.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 839.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 835.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 833.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 825.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 815.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 782.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 781.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 776.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 752.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 747.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 739.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 737.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 735.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 734.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 732.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 725.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 725.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 718.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 711.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 710.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 706.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 698.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 696.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 695.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 687.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 682.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 681.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 680.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 672.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 672.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 672.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 670.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 666.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 664.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 658.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 656.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 647.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 635.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 634.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 633.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 631.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 630.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 625.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 621.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 615.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 614.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 613.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 602.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 601.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 594.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 590.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 588.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 582.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 581.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 575.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 574.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 572.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 572.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 571.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 564.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 561.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 560.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 557.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 552.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 548.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 546.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 542.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 541.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 540.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 537.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 532.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 527.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 524.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 524.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 522.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 520.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 520.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 520.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 516.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 514.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 513.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 507.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 505.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 497.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 490.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 486.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 486.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 479.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 473.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 471.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 469.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 468.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 454.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 449.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 448.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 447.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 445.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 445.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 439.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 433.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 431.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 424.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 424.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 422.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 403.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 402.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 399.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 395.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 389.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 384.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 382.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 373.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 368.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 368.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 342.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 332.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 315.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 299.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 286.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 286.1
FF:10158-103A5 76 years, female 286.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 232.3
Pig sample Sample description nTPM
Midbrain
nTPM: 221.2
Samples: 4

Max nTPM: 337.1
Min nTPM: 152.2
Sample A Female 337.1
Sample B Female 224.8
Sample C Male 170.5
Sample D Male 152.2
Periaqueductal gray
nTPM: 165.1
Samples: 3

Max nTPM: 173.7
Min nTPM: 150.9
Sample B Female 173.7
Sample C Male 170.8
Sample D Male 150.9
Substantia nigra
nTPM: 223.3
Samples: 4

Max nTPM: 281.1
Min nTPM: 171.7
Sample A Female 281.1
Sample B Female 228.2
Sample C Male 171.7
Sample D Male 212.3
Superior colliculi
nTPM: 232.3
Samples: 4

Max nTPM: 273.2
Min nTPM: 186.8
Sample A Female 273.2
Sample B Female 264.6
Sample C Male 186.8
Sample D Male 204.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 427.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 427.4
Samples: 4

Max nTPM: 486.5
Min nTPM: 382.8
Sample A Male 486.5
Sample B Male 414.1
Sample C Female 382.8
Sample D Female 426.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.5
77464982 Antisense, RP_070129_02_F08, Mouse strain C57BL/6J (56 days, male) 7.5
77868800 Antisense, RP_070129_02_F08, Mouse strain C57BL/6J (56 days, male) 2.3

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