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RPLP0
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:602.2 nTPM
HPA:602.2 nTPM
FANTOM5:28.6 Scaled Tags Per Million
Pig:363.4 nTPM
Allen mouse:6.8 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 602.2
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 557.2
2090 Male, age 80, both hemispheres 580.4
2188 Female, age 91, both hemispheres 555.9
2301 Female, age 85, both hemispheres 552.4
1984 Male, age 76, both hemispheres 540.0
Dorsal cochlear nucleus
nTPM: 577.2
2378 Male, age 80, both hemispheres 593.4
2370 Male, age 61, both hemispheres 578.7
2802 Male, age 74, right hemisphere 575.1
2187 Female, age 91, both hemispheres 572.1
2058 Male, age 76, both hemispheres 566.5
Dorsal tegmental nucleus
nTPM: 577.8
2358 Male, age 61, both hemispheres 647.6
2083 Male, age 80, both hemispheres 565.2
2326 Male, age 74, both hemispheres 554.8
1936 Male, age 76, left hemisphere 543.6
Dorsolateral tegmental area
nTPM: 572.3
2337 Male, age 61, both hemispheres 662.3
2654 Male, age 80, both hemispheres 571.0
2751 Female, age 85, both hemispheres 546.5
2360 Male, age 74, both hemispheres 544.0
2141 Male, age 76, both hemispheres 537.8
Kolliker-Fuse nucleus
nTPM: 559.5
2315 Male, age 76, right hemisphere 588.7
2163 Male, age 80, both hemispheres 547.2
2793 Female, age 91, left hemisphere 542.5
Lateral lemniscal nuclei
nTPM: 535.1
2746 Female, age 85, left hemisphere 551.3
2036 Male, age 80, both hemispheres 533.4
2453 Male, age 74, right hemisphere 532.4
2320 Female, age 91, left hemisphere 530.1
2169 Male, age 76, both hemispheres 528.2
Lateral parabrachial nucleus
nTPM: 579.7
2790 Male, age 61, both hemispheres 602.3
2792 Male, age 76, both hemispheres 590.8
2013 Male, age 80, both hemispheres 569.6
2139 Female, age 85, right hemisphere 556.3
Lateral vestibular nucleus
nTPM: 552.1
2311 Male, age 80, both hemispheres 575.9
2184 Male, age 76, both hemispheres 528.2
Locus coeruleus
nTPM: 551.4
2123 Female, age 91, both hemispheres 556.7
2162 Male, age 80, both hemispheres 556.3
2317 Female, age 72, unknown 553.8
2720 Male, age 74, both hemispheres 551.7
2788 Male, age 74, unknown 549.7
2014 Male, age 55, unknown 546.6
1980 Male, age 76, both hemispheres 545.1
Medial olivary nucleus
nTPM: 602.2
1962 Male, age 76, both hemispheres 626.5
1943 Male, age 61, both hemispheres 619.6
2138 Female, age 91, both hemispheres 592.7
2851 Male, age 80, both hemispheres 570.1
Medial parabrachial nucleus
nTPM: 551.9
2170 Female, age 91, both hemispheres 568.2
2156 Male, age 61, both hemispheres 554.1
2463 Female, age 85, right hemisphere 547.6
2854 Male, age 80, both hemispheres 547.3
2786 Male, age 76, both hemispheres 542.2
Medial periolivary nuclei
nTPM: 548.6
2081 Male, age 80, both hemispheres 566.6
2063 Male, age 76, both hemispheres 566.1
2791 Male, age 74, right hemisphere 539.4
2458 Female, age 91, both hemispheres 539.3
2171 Female, age 85, both hemispheres 531.4
Motor facial nucleus
nTPM: 543.7
2795 Female, age 91, both hemispheres 558.5
2126 Male, age 61, both hemispheres 556.7
2062 Male, age 76, both hemispheres 550.7
2365 Male, age 74, right hemisphere 545.0
2697 Female, age 85, both hemispheres 535.2
2327 Male, age 80, both hemispheres 516.3
Motor trigeminal nucleus
nTPM: 545.2
2335 Male, age 61, both hemispheres 559.5
2560 Male, age 74, both hemispheres 555.4
2321 Female, age 91, both hemispheres 540.7
2309 Male, age 76, both hemispheres 537.4
2079 Male, age 80, both hemispheres 533.0
Nuclei of the trapezoid body
nTPM: 542.9
1983 Male, age 76, both hemispheres 569.8
2368 Female, age 91, both hemispheres 547.3
2166 Male, age 80, both hemispheres 539.5
2735 Female, age 85, both hemispheres 534.9
2159 Male, age 61, both hemispheres 522.8
Paramedian reticular nucleus
nTPM: 550.5
2052 Male, age 76, both hemispheres 563.3
2057 Male, age 80, both hemispheres 560.0
2313 Male, age 61, both hemispheres 545.2
2050 Female, age 85, both hemispheres 533.7
Pontine nuclei
nTPM: 544.1
2115 Male, age 80, left hemisphere 558.1
2787 Female, age 85, both hemispheres 555.6
2727 Male, age 61, right hemisphere 548.2
1968 Male, age 76, left hemisphere 546.0
2319 Female, age 91, both hemispheres 544.5
2109 Female, age 72, unknown 539.3
1863 Male, age 55, unknown 539.0
2454 Male, age 74, left hemisphere 521.8
Pontine raphe nucleus
nTPM: 544.9
2853 Male, age 76, midline 547.3
2122 Female, age 85, midline 542.4
Posteroventral cochlear nucleus
nTPM: 571.9
2341 Male, age 80, both hemispheres 601.0
2371 Male, age 61, both hemispheres 592.7
2135 Female, age 91, both hemispheres 574.3
2070 Male, age 76, both hemispheres 546.3
2752 Female, age 85, both hemispheres 545.1
Principal sensory trigeminal nucleus
nTPM: 533.2
2158 Male, age 61, both hemispheres 539.2
2367 Female, age 91, left hemisphere 533.5
2324 Male, age 76, both hemispheres 530.9
2008 Male, age 80, left hemisphere 529.3
Reticular pontine nucleus, caudal
nTPM: 539.5
2092 Male, age 76, both hemispheres 558.7
2457 Female, age 91, both hemispheres 543.6
2559 Male, age 74, both hemispheres 540.2
2332 Male, age 80, right hemisphere 515.5
Reticular pontine nucleus, oral
nTPM: 544.6
2361 Male, age 74, both hemispheres 562.2
1939 Male, age 80, both hemispheres 554.9
2167 Male, age 76, both hemispheres 543.8
2012 Female, age 85, both hemispheres 531.4
2366 Female, age 91, both hemispheres 530.8
Reticulotegmental nucleus
nTPM: 541.7
2452 Male, age 74, both hemispheres 552.5
2322 Female, age 91, both hemispheres 544.4
2333 Male, age 80, both hemispheres 539.3
2325 Male, age 76, both hemispheres 530.4
Spinal trigeminal nucleus, oral
nTPM: 541.1
2164 Male, age 80, both hemispheres 549.7
1978 Male, age 76, both hemispheres 543.2
2737 Female, age 85, both hemispheres 530.3
Subcoeruleus area
nTPM: 550.0
2451 Male, age 74, both hemispheres 585.6
2369 Female, age 85, left hemisphere 555.3
1958 Male, age 80, both hemispheres 541.4
2323 Female, age 91, left hemisphere 535.6
2089 Male, age 76, left hemisphere 532.1
Superior olive
nTPM: 538.9
2020 Male, age 76, both hemispheres 563.7
2561 Female, age 91, both hemispheres 550.9
2364 Male, age 74, right hemisphere 533.8
2329 Male, age 80, right hemisphere 523.9
1875 Female, age 85, both hemispheres 522.1
Superior vestibular nucleus
nTPM: 564.4
2015 Male, age 80, both hemispheres 575.9
2061 Male, age 76, both hemispheres 561.3
2383 Male, age 74, both hemispheres 556.0
Ventral periolivary nuclei
nTPM: 542.4
2023 Male, age 76, both hemispheres 566.2
2794 Female, age 91, left hemisphere 541.8
2165 Male, age 80, both hemispheres 532.5
2130 Female, age 85, both hemispheres 529.3
Ventrolateral tegmental area, A5 NE cell group
nTPM: 551.5
2359 Male, age 61, both hemispheres 589.6
2161 Male, age 80, both hemispheres 556.6
2456 Female, age 91, both hemispheres 553.0
1959 Male, age 76, both hemispheres 545.1
2840 Female, age 85, both hemispheres 534.7
2449 Male, age 74, both hemispheres 529.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 28.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 28.6
FF:10165-103B3 76 years, female 33.2
FF:10182-103D2 60 years, female 24.1
Pons
Scaled Tags Per Million: 21.8
FF:10033-101E6 18-54 years, mixed 21.8

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 363.4
Pig sample Sample description nTPM
Pons
nTPM: 363.4
Samples: 4

Max nTPM: 438.7
Min nTPM: 289.0
Sample A Female 330.2
Sample B Female 289.0
Sample C Male 438.7
Sample D Male 395.6

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.8
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 6.8
74047927 Antisense, RP_051214_02_D12, Mouse strain C57BL/6J (56 days, male) 7.1
68795446 Antisense, RP_041130_01_F11, Mouse strain C57BL/6J (56 days, male) 6.5

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.