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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:205.8 nTPM
HPA:205.8 nTPM
GTEx:185.7 nTPM
FANTOM5:110.5 Scaled Tags Per Million
Pig:200.2 nTPM
Mouse:276.9 nTPM
Allen mouse:19.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 205.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 195.9
1827 Male, age 72, unknown 204.9
2666 Male, age 74, left hemisphere 204.2
2828 Female, age 72, unknown 197.6
2019 Male, age 18, unknown 197.5
2411 Female, age 72, unknown 197.0
2219 Male, age 76, both hemispheres 194.0
2586 Male, age 75, left hemisphere 193.3
1870 Female, age 42, unknown 193.1
1833 Male, age 53, unknown 191.0
1830 Male, age 51, unknown 186.7
Dorsal raphe nucleus
nTPM: 193.0
2298 Female, age 72, unknown 202.8
2047 Male, age 72, unknown 197.2
1828 Male, age 53, unknown 193.4
2750 Male, age 76, both hemispheres 189.1
2016 Female, age 72, unknown 182.3
Inferior colliculus
nTPM: 196.1
2097 Female, age 72, unknown 202.1
2849 Male, age 72, unknown 199.0
1848 Female, age 42, unknown 193.8
1890 Male, age 53, unknown 189.6
Median raphe nucleus
nTPM: 196.6
2220 Male, age 76, midline 196.6
Pedunculopontine tegmental nucleus
nTPM: 195.1
2334 Male, age 80, both hemispheres 200.6
1921 Female, age 85, both hemispheres 196.6
2338 Male, age 61, both hemispheres 188.2
Periaquaductal grey, anterior
nTPM: 197.0
1795 Male, age 51, unknown 201.0
1947 Male, age 18, unknown 199.4
2502 Female, age 75, unknown 190.6
Periaquaductal grey, dorsal
nTPM: 190.9
2850 Male, age 76, both hemispheres 192.7
1840 Male, age 53, unknown 192.4
1831 Male, age 72, unknown 189.5
2464 Female, age 72, unknown 188.8
Periaquaductal grey, lateral
nTPM: 188.0
2272 Male, age 74, both hemispheres 191.1
2053 Male, age 18, unknown 188.1
2140 Male, age 76, both hemispheres 184.7
Pretectal area
nTPM: 205.8
1816 Male, age 51, unknown 222.8
1817 Female, age 42, unknown 221.8
1944 Female, age 72, unknown 216.4
2007 Male, age 72, unknown 213.8
2667 Female, age 75, unknown 213.0
1815 Male, age 53, unknown 210.7
2224 Female, age 72, unknown 196.5
2407 Male, age 75, both hemispheres 195.0
2273 Male, age 74, both hemispheres 193.4
2825 Male, age 18, unknown 192.9
2316 Male, age 76, right hemisphere 187.5
Red nucleus
nTPM: 191.1
2725 Female, age 75, unknown 202.0
2785 Male, age 18, unknown 199.1
1821 Female, age 72, unknown 196.3
2503 Female, age 72, unknown 191.4
2584 Male, age 75, left hemisphere 191.2
1954 Female, age 42, unknown 191.0
2823 Male, age 76, right hemisphere 188.5
2588 Male, age 74, left hemisphere 187.9
1865 Male, age 51, unknown 187.7
1904 Male, age 53, unknown 186.4
2227 Male, age 72, unknown 186.2
2769 Male, age 72, unknown 185.6
Substantia nigra
nTPM: 195.4
1889 Female, age 72, unknown 208.9
1916 Female, age 42, unknown 205.2
1941 Male, age 53, unknown 203.1
1851 Male, age 51, unknown 196.9
2583 Male, age 75, right hemisphere 195.4
2241 Male, age 72, unknown 191.4
2409 Female, age 72, unknown 190.7
2665 Male, age 74, both hemispheres 190.2
2699 Male, age 18, unknown 188.1
2590 Female, age 75, unknown 183.9
Superior colliculus
nTPM: 196.8
1796 Male, age 53, unknown 205.8
2261 Male, age 18, unknown 203.0
2087 Female, age 72, unknown 202.8
2668 Female, age 75, unknown 197.4
2587 Male, age 74, left hemisphere 195.9
1913 Female, age 42, unknown 194.5
1839 Male, age 51, unknown 194.4
1895 Male, age 76, right hemisphere 192.7
2664 Male, age 75, both hemispheres 192.1
1995 Male, age 72, unknown 189.5
Ventral tegmental area
nTPM: 194.2
2410 Female, age 72, unknown 201.4
1915 Female, age 42, unknown 198.4
2218 Male, age 76, both hemispheres 195.3
2223 Female, age 72, unknown 193.2
1942 Male, age 51, unknown 189.6
2021 Male, age 53, unknown 187.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 185.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 185.7
Samples: 139

Max nTPM: 307.7
Min nTPM: 118.3
Std nTPM: 29.3
Median nTPM: 186.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 307.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 260.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 259.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 249.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 247.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 240.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 235.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 234.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 229.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 229.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 227.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 224.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 224.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 222.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 221.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 220.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 218.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 214.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 212.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 212.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 211.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 211.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 209.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 207.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 206.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 206.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 204.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 204.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 203.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 203.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 202.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 202.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 201.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 201.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 201.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 200.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 200.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 200.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 199.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 199.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 199.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 199.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 198.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 198.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 197.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 196.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 196.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 195.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 194.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 193.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 192.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 192.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 192.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 192.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 191.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 191.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 191.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 191.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 190.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 190.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 190.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 190.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 189.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 189.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 187.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 187.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 187.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 187.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 186.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 186.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 185.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 185.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 184.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 184.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 184.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 183.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 183.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 183.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 183.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 182.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 181.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 181.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 180.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 180.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 178.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 178.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 177.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 177.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 177.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 177.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 175.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 175.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 174.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 174.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 174.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 173.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 173.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 173.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 172.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 169.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 168.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 168.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 168.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 168.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 167.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 167.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 166.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 166.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 162.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 161.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 160.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 160.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 160.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 158.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 158.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 156.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 156.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 155.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 155.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 154.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 151.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 150.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 147.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 146.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 145.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 145.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 145.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 143.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 141.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 140.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 139.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 139.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 137.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 137.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 136.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 134.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 132.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 131.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 118.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 110.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 110.5
FF:10158-103A5 76 years, female 110.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 200.2
Pig sample Sample description nTPM
Midbrain
nTPM: 200.3
Samples: 4

Max nTPM: 234.2
Min nTPM: 158.8
Sample A Female 221.4
Sample B Female 158.8
Sample C Male 234.2
Sample D Male 186.6
Periaqueductal gray
nTPM: 143.0
Samples: 3

Max nTPM: 165.6
Min nTPM: 129.7
Sample B Female 133.7
Sample C Male 165.6
Sample D Male 129.7
Substantia nigra
nTPM: 173.2
Samples: 4

Max nTPM: 211.8
Min nTPM: 131.4
Sample A Female 211.8
Sample B Female 131.4
Sample C Male 196.9
Sample D Male 152.7
Superior colliculi
nTPM: 198.5
Samples: 4

Max nTPM: 230.2
Min nTPM: 147.5
Sample A Female 230.2
Sample B Female 147.5
Sample C Male 221.1
Sample D Male 195.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 276.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 276.9
Samples: 4

Max nTPM: 302.9
Min nTPM: 257.5
Sample A Male 302.9
Sample B Male 257.5
Sample C Female 259.3
Sample D Female 288.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 19.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 19.0
513491 Antisense, RP_040810_01_H11, Mouse strain C57BL/6J (56 days, male) 19.0

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