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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:113.9 nTPM
HPA:113.9 nTPM
GTEx:126.7 nTPM
FANTOM5:215.1 Scaled Tags Per Million
Pig:89.0 nTPM
Mouse:87.8 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 113.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 107.5
2828 Female, age 72, unknown 125.3
1870 Female, age 42, unknown 119.8
2411 Female, age 72, unknown 111.3
1833 Male, age 53, unknown 108.6
1827 Male, age 72, unknown 107.1
2586 Male, age 75, left hemisphere 102.9
1830 Male, age 51, unknown 102.3
2019 Male, age 18, unknown 100.6
2666 Male, age 74, left hemisphere 99.5
2219 Male, age 76, both hemispheres 97.7
Dorsal raphe nucleus
nTPM: 113.9
2298 Female, age 72, unknown 125.5
2016 Female, age 72, unknown 121.8
2750 Male, age 76, both hemispheres 110.3
1828 Male, age 53, unknown 108.1
2047 Male, age 72, unknown 103.5
Inferior colliculus
nTPM: 103.9
2097 Female, age 72, unknown 106.4
1848 Female, age 42, unknown 105.8
2849 Male, age 72, unknown 103.3
1890 Male, age 53, unknown 100.1
Median raphe nucleus
nTPM: 104.7
2220 Male, age 76, midline 104.7
Pedunculopontine tegmental nucleus
nTPM: 101.3
1921 Female, age 85, both hemispheres 110.4
2334 Male, age 80, both hemispheres 106.5
2338 Male, age 61, both hemispheres 86.8
Periaquaductal grey, anterior
nTPM: 105.3
1795 Male, age 51, unknown 108.8
2502 Female, age 75, unknown 103.9
1947 Male, age 18, unknown 103.1
Periaquaductal grey, dorsal
nTPM: 109.9
2850 Male, age 76, both hemispheres 117.8
2464 Female, age 72, unknown 108.6
1840 Male, age 53, unknown 108.2
1831 Male, age 72, unknown 105.0
Periaquaductal grey, lateral
nTPM: 113.5
2140 Male, age 76, both hemispheres 121.1
2053 Male, age 18, unknown 120.6
2272 Male, age 74, both hemispheres 98.9
Pretectal area
nTPM: 107.1
2224 Female, age 72, unknown 116.0
2316 Male, age 76, right hemisphere 115.5
2273 Male, age 74, both hemispheres 114.9
2667 Female, age 75, unknown 112.1
2825 Male, age 18, unknown 110.5
1815 Male, age 53, unknown 110.2
1944 Female, age 72, unknown 102.5
1817 Female, age 42, unknown 102.1
2407 Male, age 75, both hemispheres 100.6
2007 Male, age 72, unknown 97.4
1816 Male, age 51, unknown 96.0
Red nucleus
nTPM: 111.7
1904 Male, age 53, unknown 121.5
2769 Male, age 72, unknown 120.6
2503 Female, age 72, unknown 120.2
2227 Male, age 72, unknown 118.4
1821 Female, age 72, unknown 117.0
2725 Female, age 75, unknown 113.5
1954 Female, age 42, unknown 113.1
1865 Male, age 51, unknown 112.9
2823 Male, age 76, right hemisphere 110.0
2785 Male, age 18, unknown 104.4
2588 Male, age 74, left hemisphere 96.9
2584 Male, age 75, left hemisphere 91.3
Substantia nigra
nTPM: 103.1
2699 Male, age 18, unknown 117.3
1851 Male, age 51, unknown 109.7
2409 Female, age 72, unknown 106.1
1889 Female, age 72, unknown 104.7
1916 Female, age 42, unknown 103.4
2583 Male, age 75, right hemisphere 101.0
2590 Female, age 75, unknown 100.2
2241 Male, age 72, unknown 98.3
1941 Male, age 53, unknown 96.4
2665 Male, age 74, both hemispheres 94.5
Superior colliculus
nTPM: 109.5
1995 Male, age 72, unknown 126.8
1913 Female, age 42, unknown 126.0
1796 Male, age 53, unknown 114.1
1839 Male, age 51, unknown 107.7
2587 Male, age 74, left hemisphere 107.1
2668 Female, age 75, unknown 105.0
1895 Male, age 76, right hemisphere 104.8
2087 Female, age 72, unknown 103.4
2664 Male, age 75, both hemispheres 100.3
2261 Male, age 18, unknown 99.8
Ventral tegmental area
nTPM: 107.2
1942 Male, age 51, unknown 112.2
2410 Female, age 72, unknown 112.0
1915 Female, age 42, unknown 108.8
2021 Male, age 53, unknown 105.4
2223 Female, age 72, unknown 102.5
2218 Male, age 76, both hemispheres 102.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 126.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 126.7
Samples: 139

Max nTPM: 257.9
Min nTPM: 33.7
Std nTPM: 40.9
Median nTPM: 119.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 257.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 247.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 224.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 212.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 205.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 205.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 204.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 201.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 195.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 194.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 191.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 185.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 184.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 184.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 184.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 180.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 180.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 173.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 173.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 172.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 171.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 169.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 168.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 163.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 163.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 162.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 161.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 161.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 159.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 158.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 157.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 156.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 154.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 152.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 147.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 147.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 147.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 147.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 147.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 146.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 146.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 146.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 145.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 145.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 144.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 144.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 142.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 142.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 141.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 141.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 139.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 138.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 138.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 137.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 136.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 133.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 131.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 129.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 129.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 127.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 126.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 126.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 126.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 126.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 126.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 121.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 120.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 119.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 119.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 119.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 118.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 118.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 116.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 116.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 115.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 115.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 114.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 114.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 112.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 112.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 112.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 111.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 111.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 110.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 110.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 110.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 108.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 107.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 106.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 106.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 106.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 105.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 105.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 105.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 105.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 102.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 102.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 102.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 101.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 101.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 100.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 100.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 99.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 99.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 98.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 97.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 97.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 96.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 96.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 95.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 94.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 92.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 91.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 91.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 91.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 90.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 88.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 87.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 87.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 85.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 84.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 84.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 81.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 81.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 78.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 76.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 76.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 75.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 74.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 73.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 72.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 69.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 69.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 67.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 67.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 57.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 47.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 47.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 33.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 215.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 215.1
FF:10158-103A5 76 years, female 215.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 89.0
Pig sample Sample description nTPM
Midbrain
nTPM: 89.0
Samples: 4

Max nTPM: 175.6
Min nTPM: 41.8
Sample A Female 175.6
Sample B Female 66.6
Sample C Male 71.9
Sample D Male 41.8
Periaqueductal gray
nTPM: 57.3
Samples: 3

Max nTPM: 62.0
Min nTPM: 51.8
Sample B Female 62.0
Sample C Male 58.2
Sample D Male 51.8
Substantia nigra
nTPM: 78.2
Samples: 4

Max nTPM: 99.7
Min nTPM: 56.6
Sample A Female 87.8
Sample B Female 56.6
Sample C Male 68.7
Sample D Male 99.7
Superior colliculi
nTPM: 71.5
Samples: 4

Max nTPM: 83.3
Min nTPM: 42.6
Sample A Female 83.3
Sample B Female 42.6
Sample C Male 82.3
Sample D Male 77.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 87.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 87.8
Samples: 4

Max nTPM: 97.9
Min nTPM: 79.3
Sample A Male 97.9
Sample B Male 79.3
Sample C Female 84.5
Sample D Female 89.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
100143511 Antisense, RP_110407_01_E08, Mouse strain C57BL/6J (56 days, male) 3.1

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