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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:148.8 nTPM
HPA:148.8 nTPM
GTEx:152.9 nTPM
FANTOM5:300.4 Scaled Tags Per Million
Pig:50.7 nTPM
Mouse:36.6 nTPM
Allen mouse:3.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 148.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 109.7
1830 Male, age 51, unknown 138.7
2019 Male, age 18, unknown 134.6
2411 Female, age 72, unknown 130.7
1870 Female, age 42, unknown 125.6
1833 Male, age 53, unknown 124.6
2828 Female, age 72, unknown 100.8
2666 Male, age 74, left hemisphere 94.0
2586 Male, age 75, left hemisphere 90.1
2219 Male, age 76, both hemispheres 79.8
1827 Male, age 72, unknown 78.2
Dorsal raphe nucleus
nTPM: 91.0
2750 Male, age 76, both hemispheres 149.9
1828 Male, age 53, unknown 90.2
2016 Female, age 72, unknown 81.0
2047 Male, age 72, unknown 75.4
2298 Female, age 72, unknown 58.4
Inferior colliculus
nTPM: 81.5
1890 Male, age 53, unknown 89.3
1848 Female, age 42, unknown 88.6
2849 Male, age 72, unknown 74.6
2097 Female, age 72, unknown 73.5
Median raphe nucleus
nTPM: 95.2
2220 Male, age 76, midline 95.2
Pedunculopontine tegmental nucleus
nTPM: 114.1
2338 Male, age 61, both hemispheres 138.5
2334 Male, age 80, both hemispheres 112.7
1921 Female, age 85, both hemispheres 91.0
Periaquaductal grey, anterior
nTPM: 71.8
2502 Female, age 75, unknown 83.2
1947 Male, age 18, unknown 72.1
1795 Male, age 51, unknown 60.2
Periaquaductal grey, dorsal
nTPM: 64.7
2464 Female, age 72, unknown 84.0
1831 Male, age 72, unknown 65.6
2850 Male, age 76, both hemispheres 56.6
1840 Male, age 53, unknown 52.7
Periaquaductal grey, lateral
nTPM: 65.9
2053 Male, age 18, unknown 73.6
2272 Male, age 74, both hemispheres 66.4
2140 Male, age 76, both hemispheres 57.7
Pretectal area
nTPM: 73.2
1815 Male, age 53, unknown 93.4
1817 Female, age 42, unknown 86.2
2316 Male, age 76, right hemisphere 83.6
2007 Male, age 72, unknown 81.5
2407 Male, age 75, both hemispheres 79.6
2825 Male, age 18, unknown 75.6
2273 Male, age 74, both hemispheres 64.7
2667 Female, age 75, unknown 63.7
1944 Female, age 72, unknown 60.5
2224 Female, age 72, unknown 59.9
1816 Male, age 51, unknown 56.0
Red nucleus
nTPM: 148.8
1865 Male, age 51, unknown 184.5
1821 Female, age 72, unknown 172.0
1904 Male, age 53, unknown 168.4
2823 Male, age 76, right hemisphere 166.5
2769 Male, age 72, unknown 163.0
2227 Male, age 72, unknown 161.5
2503 Female, age 72, unknown 148.7
1954 Female, age 42, unknown 146.9
2785 Male, age 18, unknown 139.0
2588 Male, age 74, left hemisphere 135.2
2584 Male, age 75, left hemisphere 100.5
2725 Female, age 75, unknown 99.9
Substantia nigra
nTPM: 91.8
2590 Female, age 75, unknown 105.0
2409 Female, age 72, unknown 102.4
1851 Male, age 51, unknown 100.2
2583 Male, age 75, right hemisphere 99.6
1889 Female, age 72, unknown 99.4
2699 Male, age 18, unknown 87.4
2665 Male, age 74, both hemispheres 85.7
2241 Male, age 72, unknown 84.8
1941 Male, age 53, unknown 78.7
1916 Female, age 42, unknown 74.9
Superior colliculus
nTPM: 87.6
1913 Female, age 42, unknown 108.7
1995 Male, age 72, unknown 106.3
2668 Female, age 75, unknown 100.5
2587 Male, age 74, left hemisphere 98.3
1839 Male, age 51, unknown 96.2
1895 Male, age 76, right hemisphere 90.7
2664 Male, age 75, both hemispheres 75.8
1796 Male, age 53, unknown 72.3
2087 Female, age 72, unknown 65.1
2261 Male, age 18, unknown 62.2
Ventral tegmental area
nTPM: 109.0
2223 Female, age 72, unknown 179.7
2410 Female, age 72, unknown 116.5
2218 Male, age 76, both hemispheres 98.6
2021 Male, age 53, unknown 88.9
1942 Male, age 51, unknown 88.4
1915 Female, age 42, unknown 81.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 152.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 152.9
Samples: 139

Max nTPM: 348.1
Min nTPM: 19.1
Std nTPM: 74.8
Median nTPM: 140.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 348.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 342.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 341.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 333.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 324.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 319.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 309.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 302.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 297.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 283.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 277.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 273.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 272.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 265.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 264.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 264.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 246.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 246.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 244.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 243.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 240.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 236.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 236.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 232.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 219.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 219.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 215.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 210.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 202.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 200.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 198.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 197.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 196.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 194.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 193.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 193.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 193.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 193.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 191.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 185.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 184.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 180.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 178.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 177.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 177.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 176.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 176.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 174.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 173.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 173.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 169.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 169.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 168.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 167.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 163.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 160.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 159.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 159.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 156.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 156.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 156.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 155.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 151.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 149.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 148.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 147.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 145.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 144.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 144.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 140.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 140.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 137.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 136.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 133.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 131.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 129.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 129.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 129.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 128.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 125.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 124.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 123.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 121.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 121.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 118.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 117.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 116.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 116.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 115.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 115.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 114.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 113.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 111.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 111.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 110.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 109.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 109.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 102.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 102.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 101.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 100.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 98.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 97.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 96.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 95.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 91.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 90.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 88.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 88.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 87.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 87.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 86.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 85.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 85.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 84.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 84.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 81.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 80.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 77.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 76.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 74.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 71.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 71.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 70.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 68.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 67.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 63.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 63.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 60.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 55.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 54.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 54.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 52.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 50.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 49.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 42.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 42.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 20.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 19.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 300.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 300.4
FF:10158-103A5 76 years, female 300.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 50.7
Pig sample Sample description nTPM
Midbrain
nTPM: 42.7
Samples: 4

Max nTPM: 86.1
Min nTPM: 28.0
Sample A Female 86.1
Sample B Female 28.0
Sample C Male 28.5
Sample D Male 28.1
Periaqueductal gray
nTPM: 26.9
Samples: 3

Max nTPM: 28.5
Min nTPM: 23.9
Sample B Female 28.5
Sample C Male 28.2
Sample D Male 23.9
Substantia nigra
nTPM: 38.3
Samples: 4

Max nTPM: 50.5
Min nTPM: 30.5
Sample A Female 50.5
Sample B Female 30.5
Sample C Male 33.8
Sample D Male 38.2
Superior colliculi
nTPM: 50.8
Samples: 4

Max nTPM: 80.8
Min nTPM: 29.6
Sample A Female 61.4
Sample B Female 80.8
Sample C Male 29.6
Sample D Male 31.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 36.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 36.6
Samples: 4

Max nTPM: 39.1
Min nTPM: 34.3
Sample A Male 39.1
Sample B Male 36.8
Sample C Female 34.3
Sample D Female 36.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.6
68744432 Antisense, RP_050203_02_H07, Mouse strain C57BL/6J (56 days, male) 3.6

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