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RPS16
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:794.2 nTPM
HPA:794.2 nTPM
GTEx:1110.9 nTPM
FANTOM5:341.8 Scaled Tags Per Million
Pig:752.9 nTPM
Mouse:32.7 nTPM
Allen mouse:9.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 794.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 780.0
2666 Male, age 74, left hemisphere 803.0
2586 Male, age 75, left hemisphere 802.2
1870 Female, age 42, unknown 797.0
2828 Female, age 72, unknown 782.5
2411 Female, age 72, unknown 779.9
1833 Male, age 53, unknown 773.9
1830 Male, age 51, unknown 773.2
2219 Male, age 76, both hemispheres 768.5
1827 Male, age 72, unknown 760.1
2019 Male, age 18, unknown 760.0
Dorsal raphe nucleus
nTPM: 772.4
2016 Female, age 72, unknown 780.4
2750 Male, age 76, both hemispheres 773.4
1828 Male, age 53, unknown 772.2
2298 Female, age 72, unknown 771.4
2047 Male, age 72, unknown 764.6
Inferior colliculus
nTPM: 771.7
1890 Male, age 53, unknown 784.2
2849 Male, age 72, unknown 774.7
1848 Female, age 42, unknown 766.9
2097 Female, age 72, unknown 760.9
Median raphe nucleus
nTPM: 755.4
2220 Male, age 76, midline 755.4
Pedunculopontine tegmental nucleus
nTPM: 778.8
2334 Male, age 80, both hemispheres 791.9
2338 Male, age 61, both hemispheres 789.9
1921 Female, age 85, both hemispheres 754.5
Periaquaductal grey, anterior
nTPM: 771.0
2502 Female, age 75, unknown 794.2
1795 Male, age 51, unknown 759.8
1947 Male, age 18, unknown 759.1
Periaquaductal grey, dorsal
nTPM: 762.9
1831 Male, age 72, unknown 774.6
1840 Male, age 53, unknown 765.6
2464 Female, age 72, unknown 755.9
2850 Male, age 76, both hemispheres 755.4
Periaquaductal grey, lateral
nTPM: 757.7
2053 Male, age 18, unknown 781.4
2140 Male, age 76, both hemispheres 749.7
2272 Male, age 74, both hemispheres 741.9
Pretectal area
nTPM: 764.3
2316 Male, age 76, right hemisphere 781.7
1815 Male, age 53, unknown 775.5
1817 Female, age 42, unknown 773.1
2825 Male, age 18, unknown 769.0
2407 Male, age 75, both hemispheres 767.6
2007 Male, age 72, unknown 765.6
2224 Female, age 72, unknown 763.3
1816 Male, age 51, unknown 758.0
1944 Female, age 72, unknown 756.3
2667 Female, age 75, unknown 754.9
2273 Male, age 74, both hemispheres 742.2
Red nucleus
nTPM: 794.2
2503 Female, age 72, unknown 829.6
1865 Male, age 51, unknown 810.4
1904 Male, age 53, unknown 802.2
1821 Female, age 72, unknown 799.7
2769 Male, age 72, unknown 799.3
2584 Male, age 75, left hemisphere 798.4
2227 Male, age 72, unknown 792.0
2725 Female, age 75, unknown 791.8
2785 Male, age 18, unknown 784.8
2588 Male, age 74, left hemisphere 780.6
1954 Female, age 42, unknown 771.2
2823 Male, age 76, right hemisphere 770.8
Substantia nigra
nTPM: 789.3
2699 Male, age 18, unknown 837.2
1851 Male, age 51, unknown 814.4
2665 Male, age 74, both hemispheres 808.3
2409 Female, age 72, unknown 797.4
1916 Female, age 42, unknown 782.1
2590 Female, age 75, unknown 780.0
1889 Female, age 72, unknown 777.6
2241 Male, age 72, unknown 768.7
2583 Male, age 75, right hemisphere 766.4
1941 Male, age 53, unknown 761.1
Superior colliculus
nTPM: 779.3
2587 Male, age 74, left hemisphere 808.1
1913 Female, age 42, unknown 805.8
1995 Male, age 72, unknown 805.7
1796 Male, age 53, unknown 777.9
2664 Male, age 75, both hemispheres 775.2
1839 Male, age 51, unknown 774.6
2668 Female, age 75, unknown 773.4
1895 Male, age 76, right hemisphere 772.1
2087 Female, age 72, unknown 750.9
2261 Male, age 18, unknown 749.6
Ventral tegmental area
nTPM: 781.5
1915 Female, age 42, unknown 804.0
2223 Female, age 72, unknown 787.1
2410 Female, age 72, unknown 785.1
2021 Male, age 53, unknown 777.1
1942 Male, age 51, unknown 771.0
2218 Male, age 76, both hemispheres 764.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1110.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1110.9
Samples: 139

Max nTPM: 3461.6
Min nTPM: 365.2
Std nTPM: 437.8
Median nTPM: 1018.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3461.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2798.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2513.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2423.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2001.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1840.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1825.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1778.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1773.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1723.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1610.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1597.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1578.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1570.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1564.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1558.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1547.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1527.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1497.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1497.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1476.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1452.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1444.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1427.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1388.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1388.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1382.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1369.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1366.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1357.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1351.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1315.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1296.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1286.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1278.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1273.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1272.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1269.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1263.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1249.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1243.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1238.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1233.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1232.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1227.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1227.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1214.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1212.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1203.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1202.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1200.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1199.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1182.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1181.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1180.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1165.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1132.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1131.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1130.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1129.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1120.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1103.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1103.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1095.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1069.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1058.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1052.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1036.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1029.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1018.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1016.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1015.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1011.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 995.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 988.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 988.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 969.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 967.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 966.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 962.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 960.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 945.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 938.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 930.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 927.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 927.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 920.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 912.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 910.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 903.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 902.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 899.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 893.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 878.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 875.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 874.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 871.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 866.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 854.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 852.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 849.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 841.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 833.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 832.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 830.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 829.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 820.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 810.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 805.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 796.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 795.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 773.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 758.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 746.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 745.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 740.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 734.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 719.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 715.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 707.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 693.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 691.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 690.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 689.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 689.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 686.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 681.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 674.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 673.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 662.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 646.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 627.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 601.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 594.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 545.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 529.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 457.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 441.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 365.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 341.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 341.8
FF:10158-103A5 76 years, female 341.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 752.9
Pig sample Sample description nTPM
Midbrain
nTPM: 694.4
Samples: 4

Max nTPM: 985.1
Min nTPM: 497.1
Sample A Female 985.1
Sample B Female 781.0
Sample C Male 514.2
Sample D Male 497.1
Periaqueductal gray
nTPM: 558.8
Samples: 3

Max nTPM: 612.4
Min nTPM: 527.0
Sample B Female 612.4
Sample C Male 536.9
Sample D Male 527.0
Substantia nigra
nTPM: 729.7
Samples: 4

Max nTPM: 1003.3
Min nTPM: 537.0
Sample A Female 1003.3
Sample B Female 799.3
Sample C Male 537.0
Sample D Male 579.1
Superior colliculi
nTPM: 752.9
Samples: 4

Max nTPM: 909.4
Min nTPM: 606.1
Sample A Female 909.4
Sample B Female 840.2
Sample C Male 606.1
Sample D Male 655.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 32.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 32.7
Samples: 4

Max nTPM: 45.2
Min nTPM: 24.6
Sample A Male 45.2
Sample B Male 26.7
Sample C Female 24.6
Sample D Female 34.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 9.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.5
69818379 Antisense, RP_050510_04_H09, Mouse strain C57BL/6J (56 days, male) 9.5

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