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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:128.5 nTPM
HPA:128.5 nTPM
GTEx:239.5 nTPM
FANTOM5:119.5 Scaled Tags Per Million
Pig:282.8 nTPM
Mouse:183.6 nTPM
Allen mouse:6.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 128.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 83.7
2666 Male, age 74, left hemisphere 140.9
2219 Male, age 76, both hemispheres 126.2
1827 Male, age 72, unknown 94.6
2586 Male, age 75, left hemisphere 89.7
2411 Female, age 72, unknown 82.1
1870 Female, age 42, unknown 80.1
1833 Male, age 53, unknown 65.8
2828 Female, age 72, unknown 58.9
2019 Male, age 18, unknown 49.5
1830 Male, age 51, unknown 49.2
Dorsal raphe nucleus
nTPM: 81.3
2047 Male, age 72, unknown 102.9
2298 Female, age 72, unknown 102.6
1828 Male, age 53, unknown 82.7
2750 Male, age 76, both hemispheres 72.6
2016 Female, age 72, unknown 45.7
Inferior colliculus
nTPM: 64.1
2849 Male, age 72, unknown 76.6
1848 Female, age 42, unknown 66.2
2097 Female, age 72, unknown 59.3
1890 Male, age 53, unknown 54.4
Median raphe nucleus
nTPM: 123.4
2220 Male, age 76, midline 123.4
Pedunculopontine tegmental nucleus
nTPM: 84.6
1921 Female, age 85, both hemispheres 96.6
2334 Male, age 80, both hemispheres 96.2
2338 Male, age 61, both hemispheres 61.0
Periaquaductal grey, anterior
nTPM: 81.3
1947 Male, age 18, unknown 93.1
1795 Male, age 51, unknown 91.6
2502 Female, age 75, unknown 59.1
Periaquaductal grey, dorsal
nTPM: 60.1
1840 Male, age 53, unknown 86.8
2850 Male, age 76, both hemispheres 59.0
1831 Male, age 72, unknown 56.2
2464 Female, age 72, unknown 38.3
Periaquaductal grey, lateral
nTPM: 46.0
2053 Male, age 18, unknown 51.2
2272 Male, age 74, both hemispheres 45.8
2140 Male, age 76, both hemispheres 41.0
Pretectal area
nTPM: 79.4
2007 Male, age 72, unknown 115.2
1816 Male, age 51, unknown 103.8
1944 Female, age 72, unknown 102.3
1817 Female, age 42, unknown 98.8
2224 Female, age 72, unknown 94.2
2667 Female, age 75, unknown 86.9
1815 Male, age 53, unknown 86.3
2825 Male, age 18, unknown 76.7
2407 Male, age 75, both hemispheres 56.9
2316 Male, age 76, right hemisphere 30.8
2273 Male, age 74, both hemispheres 21.5
Red nucleus
nTPM: 45.6
2584 Male, age 75, left hemisphere 113.0
1821 Female, age 72, unknown 53.8
2785 Male, age 18, unknown 53.7
2725 Female, age 75, unknown 51.8
2588 Male, age 74, left hemisphere 50.1
2769 Male, age 72, unknown 38.1
2227 Male, age 72, unknown 34.9
1954 Female, age 42, unknown 34.6
1904 Male, age 53, unknown 32.0
2503 Female, age 72, unknown 31.4
2823 Male, age 76, right hemisphere 29.7
1865 Male, age 51, unknown 24.5
Substantia nigra
nTPM: 128.5
1916 Female, age 42, unknown 242.2
1851 Male, age 51, unknown 166.8
2665 Male, age 74, both hemispheres 146.0
1941 Male, age 53, unknown 135.0
2699 Male, age 18, unknown 121.1
2241 Male, age 72, unknown 115.0
1889 Female, age 72, unknown 109.4
2409 Female, age 72, unknown 100.5
2583 Male, age 75, right hemisphere 90.5
2590 Female, age 75, unknown 58.2
Superior colliculus
nTPM: 67.1
2668 Female, age 75, unknown 134.0
1796 Male, age 53, unknown 97.9
2087 Female, age 72, unknown 67.8
2261 Male, age 18, unknown 67.6
1839 Male, age 51, unknown 65.7
1895 Male, age 76, right hemisphere 65.7
2664 Male, age 75, both hemispheres 60.0
2587 Male, age 74, left hemisphere 54.3
1913 Female, age 42, unknown 33.7
1995 Male, age 72, unknown 24.0
Ventral tegmental area
nTPM: 126.4
1915 Female, age 42, unknown 173.8
2218 Male, age 76, both hemispheres 168.2
2410 Female, age 72, unknown 137.2
1942 Male, age 51, unknown 116.3
2223 Female, age 72, unknown 87.3
2021 Male, age 53, unknown 75.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 239.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 239.5
Samples: 139

Max nTPM: 717.5
Min nTPM: 78.5
Std nTPM: 145.5
Median nTPM: 197.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 717.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 675.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 672.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 661.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 586.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 570.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 565.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 564.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 557.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 523.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 520.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 487.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 464.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 455.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 451.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 419.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 415.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 412.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 409.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 407.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 403.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 374.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 368.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 368.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 363.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 361.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 346.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 345.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 333.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 320.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 314.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 312.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 312.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 308.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 301.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 294.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 294.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 287.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 284.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 283.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 280.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 275.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 274.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 271.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 270.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 268.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 268.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 267.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 266.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 261.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 260.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 254.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 254.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 245.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 245.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 244.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 243.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 243.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 232.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 230.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 227.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 214.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 207.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 207.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 204.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 204.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 201.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 200.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 198.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 197.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 192.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 191.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 187.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 183.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 182.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 181.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 178.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 175.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 170.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 168.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 168.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 165.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 163.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 161.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 161.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 158.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 157.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 154.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 153.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 150.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 148.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 146.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 145.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 145.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 142.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 142.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 138.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 136.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 134.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 133.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 132.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 129.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 129.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 127.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 126.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 124.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 123.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 123.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 121.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 121.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 120.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 120.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 118.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 115.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 114.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 114.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 112.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 110.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 104.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 103.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 100.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 99.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 98.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 95.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 95.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 94.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 94.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 93.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 93.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 93.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 92.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 91.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 90.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 90.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 90.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 88.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 84.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 80.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 78.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 119.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 119.5
FF:10158-103A5 76 years, female 119.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 282.8
Pig sample Sample description nTPM
Midbrain
nTPM: 269.9
Samples: 4

Max nTPM: 385.6
Min nTPM: 133.6
Sample A Female 133.6
Sample B Female 198.5
Sample C Male 385.6
Sample D Male 361.8
Periaqueductal gray
nTPM: 233.7
Samples: 3

Max nTPM: 314.9
Min nTPM: 185.1
Sample B Female 185.1
Sample C Male 314.9
Sample D Male 201.1
Substantia nigra
nTPM: 261.2
Samples: 4

Max nTPM: 384.0
Min nTPM: 105.6
Sample A Female 364.4
Sample B Female 190.6
Sample C Male 384.0
Sample D Male 105.6
Superior colliculi
nTPM: 282.8
Samples: 4

Max nTPM: 345.8
Min nTPM: 159.8
Sample A Female 345.8
Sample B Female 159.8
Sample C Male 301.0
Sample D Male 324.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 183.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 183.6
Samples: 4

Max nTPM: 188.4
Min nTPM: 178.9
Sample A Male 188.4
Sample B Male 180.7
Sample C Female 178.9
Sample D Female 186.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.1
77464848 Antisense, RP_070129_02_B12, Mouse strain C57BL/6J (56 days, male) 16.9
808 Antisense, RP_Baylor_102968, Mouse strain C57BL/6J (56 days, male) 1.5
809 Antisense, RP_Baylor_102968, Mouse strain C57BL/6J (56 days, male) 1.2
810 Sense, RPS_Baylor_37025, Mouse strain C57BL/6J (56 days, male) 0.0

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