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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:124.8 nTPM
HPA:124.8 nTPM
GTEx:181.8 nTPM
FANTOM5:76.1 Scaled Tags Per Million
Pig:84.1 nTPM
Mouse:81.4 nTPM
Allen mouse:2.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 124.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 118.2
2019 Male, age 18, unknown 125.5
2411 Female, age 72, unknown 122.1
2828 Female, age 72, unknown 120.9
1827 Male, age 72, unknown 120.7
1870 Female, age 42, unknown 120.2
2586 Male, age 75, left hemisphere 119.3
1833 Male, age 53, unknown 115.0
2666 Male, age 74, left hemisphere 115.0
2219 Male, age 76, both hemispheres 112.8
1830 Male, age 51, unknown 110.2
Dorsal raphe nucleus
nTPM: 115.3
1828 Male, age 53, unknown 120.7
2750 Male, age 76, both hemispheres 119.7
2298 Female, age 72, unknown 114.1
2047 Male, age 72, unknown 111.4
2016 Female, age 72, unknown 110.6
Inferior colliculus
nTPM: 112.7
1890 Male, age 53, unknown 117.3
2097 Female, age 72, unknown 116.2
1848 Female, age 42, unknown 110.2
2849 Male, age 72, unknown 107.2
Median raphe nucleus
nTPM: 114.6
2220 Male, age 76, midline 114.6
Pedunculopontine tegmental nucleus
nTPM: 119.3
2334 Male, age 80, both hemispheres 122.0
2338 Male, age 61, both hemispheres 118.7
1921 Female, age 85, both hemispheres 117.1
Periaquaductal grey, anterior
nTPM: 114.9
1795 Male, age 51, unknown 117.0
1947 Male, age 18, unknown 114.0
2502 Female, age 75, unknown 113.6
Periaquaductal grey, dorsal
nTPM: 109.1
1831 Male, age 72, unknown 114.2
2464 Female, age 72, unknown 111.4
1840 Male, age 53, unknown 106.3
2850 Male, age 76, both hemispheres 104.5
Periaquaductal grey, lateral
nTPM: 108.0
2272 Male, age 74, both hemispheres 109.1
2053 Male, age 18, unknown 108.3
2140 Male, age 76, both hemispheres 106.4
Pretectal area
nTPM: 118.9
2007 Male, age 72, unknown 130.3
1816 Male, age 51, unknown 130.2
1817 Female, age 42, unknown 129.6
1944 Female, age 72, unknown 127.5
1815 Male, age 53, unknown 121.7
2667 Female, age 75, unknown 121.3
2316 Male, age 76, right hemisphere 111.3
2273 Male, age 74, both hemispheres 110.4
2224 Female, age 72, unknown 110.1
2825 Male, age 18, unknown 109.4
2407 Male, age 75, both hemispheres 105.7
Red nucleus
nTPM: 124.8
2503 Female, age 72, unknown 134.0
2588 Male, age 74, left hemisphere 127.6
1821 Female, age 72, unknown 126.8
1954 Female, age 42, unknown 126.7
2785 Male, age 18, unknown 126.0
2769 Male, age 72, unknown 124.4
1904 Male, age 53, unknown 124.3
1865 Male, age 51, unknown 123.7
2227 Male, age 72, unknown 123.4
2823 Male, age 76, right hemisphere 122.9
2725 Female, age 75, unknown 122.4
2584 Male, age 75, left hemisphere 115.9
Substantia nigra
nTPM: 117.8
1851 Male, age 51, unknown 125.7
1889 Female, age 72, unknown 124.7
1916 Female, age 42, unknown 124.0
2699 Male, age 18, unknown 117.6
2409 Female, age 72, unknown 116.9
2665 Male, age 74, both hemispheres 116.0
1941 Male, age 53, unknown 115.7
2590 Female, age 75, unknown 114.1
2583 Male, age 75, right hemisphere 112.7
2241 Male, age 72, unknown 110.5
Superior colliculus
nTPM: 116.5
2087 Female, age 72, unknown 125.1
1913 Female, age 42, unknown 122.3
2668 Female, age 75, unknown 119.7
1796 Male, age 53, unknown 119.1
2261 Male, age 18, unknown 117.9
1995 Male, age 72, unknown 116.0
1895 Male, age 76, right hemisphere 115.5
2587 Male, age 74, left hemisphere 113.3
2664 Male, age 75, both hemispheres 109.0
1839 Male, age 51, unknown 107.6
Ventral tegmental area
nTPM: 117.9
1915 Female, age 42, unknown 122.7
2410 Female, age 72, unknown 121.0
2223 Female, age 72, unknown 119.0
2218 Male, age 76, both hemispheres 118.3
1942 Male, age 51, unknown 116.6
2021 Male, age 53, unknown 109.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 181.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 181.8
Samples: 139

Max nTPM: 428.9
Min nTPM: 71.8
Std nTPM: 48.7
Median nTPM: 172.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 428.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 416.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 301.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 291.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 289.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 288.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 285.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 266.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 255.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 255.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 239.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 238.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 233.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 231.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 231.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 230.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 229.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 227.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 224.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 223.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 222.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 214.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 214.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 211.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 211.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 211.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 207.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 207.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 207.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 205.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 205.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 204.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 204.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 204.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 202.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 201.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 200.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 199.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 198.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 197.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 196.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 195.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 194.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 192.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 192.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 191.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 190.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 190.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 189.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 188.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 184.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 183.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 183.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 181.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 181.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 180.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 180.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 177.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 177.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 176.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 176.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 176.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 175.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 175.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 174.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 173.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 173.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 172.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 172.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 172.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 172.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 171.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 171.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 171.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 171.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 169.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 168.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 168.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 168.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 167.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 165.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 165.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 164.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 164.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 162.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 162.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 162.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 162.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 160.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 159.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 159.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 159.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 158.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 157.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 157.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 156.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 156.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 156.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 155.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 155.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 155.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 154.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 154.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 151.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 150.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 149.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 149.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 149.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 149.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 149.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 149.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 149.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 146.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 145.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 144.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 144.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 144.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 143.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 142.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 142.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 141.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 140.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 140.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 139.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 134.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 134.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 134.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 134.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 133.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 132.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 128.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 128.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 126.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 120.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 118.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 118.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 118.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 108.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 71.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 76.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 76.1
FF:10158-103A5 76 years, female 76.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 84.1
Pig sample Sample description nTPM
Midbrain
nTPM: 83.9
Samples: 4

Max nTPM: 117.9
Min nTPM: 52.6
Sample A Female 117.9
Sample B Female 87.3
Sample C Male 77.8
Sample D Male 52.6
Periaqueductal gray
nTPM: 68.6
Samples: 3

Max nTPM: 77.9
Min nTPM: 55.0
Sample B Female 72.9
Sample C Male 77.9
Sample D Male 55.0
Substantia nigra
nTPM: 81.0
Samples: 4

Max nTPM: 107.2
Min nTPM: 62.8
Sample A Female 107.2
Sample B Female 62.8
Sample C Male 90.9
Sample D Male 63.2
Superior colliculi
nTPM: 84.1
Samples: 4

Max nTPM: 98.6
Min nTPM: 72.4
Sample A Female 98.6
Sample B Female 75.1
Sample C Male 90.3
Sample D Male 72.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 81.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 81.4
Samples: 4

Max nTPM: 94.4
Min nTPM: 70.0
Sample A Male 94.4
Sample B Male 70.0
Sample C Female 73.9
Sample D Female 87.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.4
69262325 Antisense, RP_050303_02_A06, Mouse strain C57BL/6J (56 days, male) 2.4

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