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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:220.1 nTPM
HPA:220.1 nTPM
FANTOM5:534.8 Scaled Tags Per Million
Pig:221.5 nTPM
Allen mouse:13.7 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 220.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 112.1
1984 Male, age 76, both hemispheres 164.6
2301 Female, age 85, both hemispheres 118.3
2090 Male, age 80, both hemispheres 86.5
2188 Female, age 91, both hemispheres 78.9
Dorsal cochlear nucleus
nTPM: 133.5
2802 Male, age 74, right hemisphere 184.1
2058 Male, age 76, both hemispheres 140.0
2370 Male, age 61, both hemispheres 132.5
2378 Male, age 80, both hemispheres 108.8
2187 Female, age 91, both hemispheres 102.4
Dorsal tegmental nucleus
nTPM: 122.3
2083 Male, age 80, both hemispheres 143.2
1936 Male, age 76, left hemisphere 130.8
2326 Male, age 74, both hemispheres 108.6
2358 Male, age 61, both hemispheres 106.4
Dorsolateral tegmental area
nTPM: 111.9
2141 Male, age 76, both hemispheres 167.3
2654 Male, age 80, both hemispheres 126.3
2751 Female, age 85, both hemispheres 112.0
2360 Male, age 74, both hemispheres 93.9
2337 Male, age 61, both hemispheres 60.0
Kolliker-Fuse nucleus
nTPM: 130.3
2163 Male, age 80, both hemispheres 163.5
2315 Male, age 76, right hemisphere 122.9
2793 Female, age 91, left hemisphere 104.4
Lateral lemniscal nuclei
nTPM: 176.5
2169 Male, age 76, both hemispheres 218.6
2453 Male, age 74, right hemisphere 195.8
2036 Male, age 80, both hemispheres 195.6
2746 Female, age 85, left hemisphere 153.5
2320 Female, age 91, left hemisphere 118.9
Lateral parabrachial nucleus
nTPM: 123.5
2139 Female, age 85, right hemisphere 187.6
2790 Male, age 61, both hemispheres 130.9
2013 Male, age 80, both hemispheres 110.1
2792 Male, age 76, both hemispheres 65.2
Lateral vestibular nucleus
nTPM: 140.4
2184 Male, age 76, both hemispheres 170.1
2311 Male, age 80, both hemispheres 110.8
Locus coeruleus
nTPM: 167.0
2123 Female, age 91, both hemispheres 207.3
2317 Female, age 72, unknown 171.8
2720 Male, age 74, both hemispheres 169.6
1980 Male, age 76, both hemispheres 169.4
2162 Male, age 80, both hemispheres 159.4
2014 Male, age 55, unknown 159.2
2788 Male, age 74, unknown 132.6
Medial olivary nucleus
nTPM: 82.4
2138 Female, age 91, both hemispheres 105.1
2851 Male, age 80, both hemispheres 101.0
1962 Male, age 76, both hemispheres 75.9
1943 Male, age 61, both hemispheres 47.7
Medial parabrachial nucleus
nTPM: 123.8
2854 Male, age 80, both hemispheres 141.7
2156 Male, age 61, both hemispheres 130.7
2786 Male, age 76, both hemispheres 128.5
2463 Female, age 85, right hemisphere 113.5
2170 Female, age 91, both hemispheres 104.7
Medial periolivary nuclei
nTPM: 179.1
2063 Male, age 76, both hemispheres 263.6
2171 Female, age 85, both hemispheres 245.5
2791 Male, age 74, right hemisphere 155.6
2458 Female, age 91, both hemispheres 117.7
2081 Male, age 80, both hemispheres 113.0
Motor facial nucleus
nTPM: 192.9
2062 Male, age 76, both hemispheres 280.5
2327 Male, age 80, both hemispheres 222.7
2795 Female, age 91, both hemispheres 193.0
2697 Female, age 85, both hemispheres 160.5
2365 Male, age 74, right hemisphere 155.5
2126 Male, age 61, both hemispheres 144.9
Motor trigeminal nucleus
nTPM: 143.4
2079 Male, age 80, both hemispheres 191.7
2560 Male, age 74, both hemispheres 157.4
2309 Male, age 76, both hemispheres 130.0
2335 Male, age 61, both hemispheres 128.9
2321 Female, age 91, both hemispheres 108.9
Nuclei of the trapezoid body
nTPM: 220.1
2735 Female, age 85, both hemispheres 263.5
2159 Male, age 61, both hemispheres 253.9
1983 Male, age 76, both hemispheres 247.4
2166 Male, age 80, both hemispheres 174.0
2368 Female, age 91, both hemispheres 161.9
Paramedian reticular nucleus
nTPM: 149.1
2050 Female, age 85, both hemispheres 185.1
2313 Male, age 61, both hemispheres 167.7
2057 Male, age 80, both hemispheres 163.9
2052 Male, age 76, both hemispheres 79.6
Pontine nuclei
nTPM: 183.1
2787 Female, age 85, both hemispheres 263.1
2727 Male, age 61, right hemisphere 241.1
1968 Male, age 76, left hemisphere 223.7
1863 Male, age 55, unknown 211.6
2109 Female, age 72, unknown 191.7
2115 Male, age 80, left hemisphere 131.7
2454 Male, age 74, left hemisphere 117.4
2319 Female, age 91, both hemispheres 84.2
Pontine raphe nucleus
nTPM: 190.2
2122 Female, age 85, midline 205.0
2853 Male, age 76, midline 175.4
Posteroventral cochlear nucleus
nTPM: 100.1
2752 Female, age 85, both hemispheres 156.8
2070 Male, age 76, both hemispheres 128.3
2371 Male, age 61, both hemispheres 118.8
2341 Male, age 80, both hemispheres 65.9
2135 Female, age 91, both hemispheres 30.6
Principal sensory trigeminal nucleus
nTPM: 181.8
2158 Male, age 61, both hemispheres 276.1
2008 Male, age 80, left hemisphere 198.4
2324 Male, age 76, both hemispheres 157.5
2367 Female, age 91, left hemisphere 95.1
Reticular pontine nucleus, caudal
nTPM: 157.8
2332 Male, age 80, right hemisphere 231.6
2092 Male, age 76, both hemispheres 176.3
2457 Female, age 91, both hemispheres 118.8
2559 Male, age 74, both hemispheres 104.6
Reticular pontine nucleus, oral
nTPM: 124.8
2012 Female, age 85, both hemispheres 160.7
2361 Male, age 74, both hemispheres 126.8
1939 Male, age 80, both hemispheres 123.1
2167 Male, age 76, both hemispheres 122.2
2366 Female, age 91, both hemispheres 91.0
Reticulotegmental nucleus
nTPM: 163.2
2325 Male, age 76, both hemispheres 193.1
2452 Male, age 74, both hemispheres 168.9
2333 Male, age 80, both hemispheres 163.3
2322 Female, age 91, both hemispheres 127.7
Spinal trigeminal nucleus, oral
nTPM: 141.3
2737 Female, age 85, both hemispheres 156.5
2164 Male, age 80, both hemispheres 155.7
1978 Male, age 76, both hemispheres 111.8
Subcoeruleus area
nTPM: 143.5
2089 Male, age 76, left hemisphere 185.8
2323 Female, age 91, left hemisphere 158.6
1958 Male, age 80, both hemispheres 154.8
2451 Male, age 74, both hemispheres 132.0
2369 Female, age 85, left hemisphere 86.4
Superior olive
nTPM: 164.4
1875 Female, age 85, both hemispheres 198.3
2329 Male, age 80, right hemisphere 182.9
2020 Male, age 76, both hemispheres 161.2
2561 Female, age 91, both hemispheres 146.4
2364 Male, age 74, right hemisphere 133.0
Superior vestibular nucleus
nTPM: 108.5
2061 Male, age 76, both hemispheres 126.7
2015 Male, age 80, both hemispheres 121.7
2383 Male, age 74, both hemispheres 77.1
Ventral periolivary nuclei
nTPM: 194.1
2130 Female, age 85, both hemispheres 262.0
2165 Male, age 80, both hemispheres 226.9
2794 Female, age 91, left hemisphere 148.5
2023 Male, age 76, both hemispheres 138.8
Ventrolateral tegmental area, A5 NE cell group
nTPM: 150.9
1959 Male, age 76, both hemispheres 182.8
2449 Male, age 74, both hemispheres 174.3
2161 Male, age 80, both hemispheres 162.7
2840 Female, age 85, both hemispheres 139.2
2456 Female, age 91, both hemispheres 131.7
2359 Male, age 61, both hemispheres 114.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 534.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 331.7
FF:10182-103D2 60 years, female 423.2
FF:10165-103B3 76 years, female 240.2
Pons
Scaled Tags Per Million: 534.8
FF:10033-101E6 18-54 years, mixed 534.8

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 221.5
Pig sample Sample description nTPM
Pons
nTPM: 221.6
Samples: 4

Max nTPM: 374.8
Min nTPM: 156.4
Sample A Female 374.8
Sample B Female 167.3
Sample C Male 156.4
Sample D Male 187.7

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 13.7
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 13.7
69262230 Antisense, RP_050301_01_F10, Mouse strain C57BL/6J (56 days, male) 18.1
70812774 Antisense, RP_050712_02_E12, Mouse strain C57BL/6J (56 days, male) 9.4

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.