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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:494.2 nTPM
HPA:494.2 nTPM
GTEx:456.2 nTPM
FANTOM5:615.2 Scaled Tags Per Million
Pig:656.1 nTPM
Mouse:2567.3 nTPM
Allen mouse:17.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 494.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 415.6
2828 Female, age 72, unknown 507.8
1827 Male, age 72, unknown 455.5
2219 Male, age 76, both hemispheres 447.1
2586 Male, age 75, left hemisphere 444.9
1870 Female, age 42, unknown 430.2
2019 Male, age 18, unknown 390.2
2411 Female, age 72, unknown 384.2
1833 Male, age 53, unknown 383.6
1830 Male, age 51, unknown 360.8
2666 Male, age 74, left hemisphere 351.7
Dorsal raphe nucleus
nTPM: 450.8
2298 Female, age 72, unknown 492.4
2016 Female, age 72, unknown 487.8
2047 Male, age 72, unknown 445.5
1828 Male, age 53, unknown 444.3
2750 Male, age 76, both hemispheres 384.2
Inferior colliculus
nTPM: 444.4
2097 Female, age 72, unknown 468.4
1848 Female, age 42, unknown 458.4
1890 Male, age 53, unknown 427.2
2849 Male, age 72, unknown 423.5
Median raphe nucleus
nTPM: 423.5
2220 Male, age 76, midline 423.5
Pedunculopontine tegmental nucleus
nTPM: 394.1
1921 Female, age 85, both hemispheres 469.7
2334 Male, age 80, both hemispheres 397.4
2338 Male, age 61, both hemispheres 315.3
Periaquaductal grey, anterior
nTPM: 442.6
1795 Male, age 51, unknown 486.4
1947 Male, age 18, unknown 432.5
2502 Female, age 75, unknown 408.8
Periaquaductal grey, dorsal
nTPM: 479.8
1840 Male, age 53, unknown 511.9
2850 Male, age 76, both hemispheres 491.9
1831 Male, age 72, unknown 487.4
2464 Female, age 72, unknown 428.2
Periaquaductal grey, lateral
nTPM: 475.6
2053 Male, age 18, unknown 502.3
2272 Male, age 74, both hemispheres 470.3
2140 Male, age 76, both hemispheres 454.3
Pretectal area
nTPM: 494.2
2273 Male, age 74, both hemispheres 590.6
2667 Female, age 75, unknown 555.6
1944 Female, age 72, unknown 554.4
2224 Female, age 72, unknown 512.9
1817 Female, age 42, unknown 503.2
1816 Male, age 51, unknown 494.1
1815 Male, age 53, unknown 477.0
2825 Male, age 18, unknown 455.1
2007 Male, age 72, unknown 442.9
2407 Male, age 75, both hemispheres 434.0
2316 Male, age 76, right hemisphere 416.5
Red nucleus
nTPM: 382.0
2725 Female, age 75, unknown 441.9
1821 Female, age 72, unknown 423.7
2503 Female, age 72, unknown 420.0
2769 Male, age 72, unknown 383.8
2227 Male, age 72, unknown 378.6
2785 Male, age 18, unknown 378.5
1954 Female, age 42, unknown 377.0
1865 Male, age 51, unknown 373.9
1904 Male, age 53, unknown 372.2
2823 Male, age 76, right hemisphere 369.8
2588 Male, age 74, left hemisphere 350.3
2584 Male, age 75, left hemisphere 314.9
Substantia nigra
nTPM: 445.6
1916 Female, age 42, unknown 541.5
1889 Female, age 72, unknown 482.3
1851 Male, age 51, unknown 475.5
2699 Male, age 18, unknown 474.1
2409 Female, age 72, unknown 447.5
1941 Male, age 53, unknown 438.7
2241 Male, age 72, unknown 431.0
2590 Female, age 75, unknown 392.5
2665 Male, age 74, both hemispheres 388.2
2583 Male, age 75, right hemisphere 384.5
Superior colliculus
nTPM: 442.9
2087 Female, age 72, unknown 513.1
1796 Male, age 53, unknown 486.1
1995 Male, age 72, unknown 457.7
2261 Male, age 18, unknown 451.7
2664 Male, age 75, both hemispheres 437.3
1839 Male, age 51, unknown 426.7
1913 Female, age 42, unknown 425.3
2587 Male, age 74, left hemisphere 418.4
2668 Female, age 75, unknown 409.3
1895 Male, age 76, right hemisphere 403.4
Ventral tegmental area
nTPM: 442.3
1915 Female, age 42, unknown 474.1
1942 Male, age 51, unknown 449.5
2410 Female, age 72, unknown 448.4
2021 Male, age 53, unknown 447.7
2218 Male, age 76, both hemispheres 437.6
2223 Female, age 72, unknown 396.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 456.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 456.2
Samples: 139

Max nTPM: 1414.5
Min nTPM: 89.5
Std nTPM: 221.3
Median nTPM: 428.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1414.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1206.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1202.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1001.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 988.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 939.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 880.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 869.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 804.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 791.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 787.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 752.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 749.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 745.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 740.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 739.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 697.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 683.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 673.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 656.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 640.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 640.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 619.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 618.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 599.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 596.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 596.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 584.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 579.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 579.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 572.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 571.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 566.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 560.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 560.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 558.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 556.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 555.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 549.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 540.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 527.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 520.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 517.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 516.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 507.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 505.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 503.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 499.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 492.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 492.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 489.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 478.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 471.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 468.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 467.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 467.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 465.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 463.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 461.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 461.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 458.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 447.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 445.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 445.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 444.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 443.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 441.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 439.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 437.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 428.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 426.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 420.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 416.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 413.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 412.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 411.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 410.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 401.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 399.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 396.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 393.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 391.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 391.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 385.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 385.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 380.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 365.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 363.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 349.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 338.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 335.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 333.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 332.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 321.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 319.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 318.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 317.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 310.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 304.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 302.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 300.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 296.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 295.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 294.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 290.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 290.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 290.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 287.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 284.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 283.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 279.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 275.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 266.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 264.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 263.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 263.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 263.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 253.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 249.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 241.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 240.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 230.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 224.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 219.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 215.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 214.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 214.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 213.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 212.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 212.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 211.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 199.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 191.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 189.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 168.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 153.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 145.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 109.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 89.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 615.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 615.2
FF:10158-103A5 76 years, female 615.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 656.1
Pig sample Sample description nTPM
Midbrain
nTPM: 631.8
Samples: 4

Max nTPM: 734.2
Min nTPM: 506.7
Sample A Female 734.2
Sample B Female 680.2
Sample C Male 606.1
Sample D Male 506.7
Periaqueductal gray
nTPM: 656.1
Samples: 3

Max nTPM: 757.4
Min nTPM: 544.1
Sample B Female 757.4
Sample C Male 666.9
Sample D Male 544.1
Substantia nigra
nTPM: 613.4
Samples: 4

Max nTPM: 661.9
Min nTPM: 537.8
Sample A Female 661.9
Sample B Female 537.8
Sample C Male 631.9
Sample D Male 622.0
Superior colliculi
nTPM: 501.3
Samples: 4

Max nTPM: 587.9
Min nTPM: 329.6
Sample A Female 587.9
Sample B Female 329.6
Sample C Male 553.3
Sample D Male 534.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 2567.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 2567.4
Samples: 4

Max nTPM: 2699.2
Min nTPM: 2418.0
Sample A Male 2605.7
Sample B Male 2418.0
Sample C Female 2699.2
Sample D Female 2546.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 17.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.7
1692 Antisense, RP_Baylor_102700, Mouse strain C57BL/6J (56 days, male) 17.7
1691 Antisense, RP_Baylor_102700, Mouse strain C57BL/6J (56 days, male) 9.5

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