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EIF4G2
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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:196.9 nTPM
HPA:196.9 nTPM
FANTOM5:1526.1 Scaled Tags Per Million
Pig:336.1 nTPM
Mouse:340.3 nTPM
Allen mouse:6.4 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 196.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 166.7
2301 Female, age 85, both hemispheres 180.7
2188 Female, age 91, both hemispheres 170.5
2090 Male, age 80, both hemispheres 160.0
1984 Male, age 76, both hemispheres 155.4
Area postrema
nTPM: 180.7
2799 Male, age 61, both hemispheres 189.2
2306 Male, age 80, both hemispheres 184.7
2054 Male, age 76, both hemispheres 168.0
Cuneate nuclei
nTPM: 160.8
2131 Male, age 76, both hemispheres 164.2
2381 Male, age 80, both hemispheres 161.3
2376 Male, age 61, both hemispheres 156.9
Dorsal cochlear nucleus
nTPM: 171.4
2802 Male, age 74, right hemisphere 192.5
2187 Female, age 91, both hemispheres 172.9
2378 Male, age 80, both hemispheres 165.3
2058 Male, age 76, both hemispheres 164.9
2370 Male, age 61, both hemispheres 161.2
Dorsal medullary reticular nucleus
nTPM: 173.9
2040 Female, age 85, both hemispheres 200.3
2373 Male, age 61, both hemispheres 168.3
2088 Male, age 76, both hemispheres 152.9
Dorsal motor vagal complex
nTPM: 167.9
2000 Male, age 74, unknown 180.6
2133 Female, age 91, both hemispheres 180.4
2844 Male, age 55, unknown 174.2
2643 Male, age 74, both hemispheres 171.6
2813 Female, age 72, unknown 171.5
2797 Male, age 61, both hemispheres 165.2
2185 Male, age 76, both hemispheres 154.7
2807 Female, age 85, both hemispheres 144.7
Dorsal tegmental nucleus
nTPM: 182.4
2358 Male, age 61, both hemispheres 191.2
2326 Male, age 74, both hemispheres 187.4
2083 Male, age 80, both hemispheres 185.6
1936 Male, age 76, left hemisphere 165.2
Dorsolateral tegmental area
nTPM: 174.5
2654 Male, age 80, both hemispheres 189.5
2751 Female, age 85, both hemispheres 188.6
2141 Male, age 76, both hemispheres 175.2
2337 Male, age 61, both hemispheres 168.9
2360 Male, age 74, both hemispheres 150.6
Gigantocellular reticular nuclei, medullary
nTPM: 175.7
2314 Male, age 61, both hemispheres 186.3
1876 Female, age 85, both hemispheres 185.3
2462 Male, age 74, both hemispheres 173.7
2387 Female, age 91, both hemispheres 173.1
2022 Male, age 76, right hemisphere 171.0
2310 Male, age 80, both hemispheres 164.6
Gigantocellular reticular nuclei, pars
nTPM: 172.4
2168 Male, age 76, both hemispheres 183.6
2084 Female, age 85, both hemispheres 180.9
2336 Male, age 61, both hemispheres 178.0
2330 Male, age 80, both hemispheres 164.2
2706 Male, age 80, both hemispheres 155.1
Inferior olive
nTPM: 190.0
2563 Male, age 74, both hemispheres 218.0
2085 Female, age 85, both hemispheres 197.7
2628 Female, age 91, both hemispheres 190.5
2379 Male, age 80, both hemispheres 174.7
2178 Male, age 61, both hemispheres 168.9
Kolliker-Fuse nucleus
nTPM: 182.2
2315 Male, age 76, right hemisphere 184.2
2163 Male, age 80, both hemispheres 182.1
2793 Female, age 91, left hemisphere 180.4
Lateral lemniscal nuclei
nTPM: 171.9
2169 Male, age 76, both hemispheres 192.2
2453 Male, age 74, right hemisphere 172.5
2746 Female, age 85, left hemisphere 168.8
2036 Male, age 80, both hemispheres 167.2
2320 Female, age 91, left hemisphere 159.0
Lateral medullary reticular nucleus
nTPM: 186.7
2374 Male, age 61, both hemispheres 199.0
2804 Female, age 91, both hemispheres 191.9
2044 Male, age 76, both hemispheres 189.9
2305 Male, age 74, both hemispheres 182.7
2190 Female, age 85, both hemispheres 180.5
2852 Male, age 80, both hemispheres 175.9
Lateral parabrachial nucleus
nTPM: 171.4
2139 Female, age 85, right hemisphere 182.3
2792 Male, age 76, both hemispheres 177.2
2013 Male, age 80, both hemispheres 173.3
2790 Male, age 61, both hemispheres 152.9
Lateral vestibular nucleus
nTPM: 178.0
2184 Male, age 76, both hemispheres 178.4
2311 Male, age 80, both hemispheres 177.6
Locus coeruleus
nTPM: 196.8
2014 Male, age 55, unknown 214.4
2317 Female, age 72, unknown 206.5
2788 Male, age 74, unknown 200.5
1980 Male, age 76, both hemispheres 196.6
2123 Female, age 91, both hemispheres 195.2
2720 Male, age 74, both hemispheres 187.0
2162 Male, age 80, both hemispheres 177.6
Medial olivary nucleus
nTPM: 179.0
1962 Male, age 76, both hemispheres 182.1
2138 Female, age 91, both hemispheres 180.3
2851 Male, age 80, both hemispheres 179.4
1943 Male, age 61, both hemispheres 174.2
Medial parabrachial nucleus
nTPM: 174.2
2170 Female, age 91, both hemispheres 187.2
2854 Male, age 80, both hemispheres 182.4
2786 Male, age 76, both hemispheres 170.3
2156 Male, age 61, both hemispheres 168.1
2463 Female, age 85, right hemisphere 163.2
Medial periolivary nuclei
nTPM: 169.7
2063 Male, age 76, both hemispheres 189.7
2171 Female, age 85, both hemispheres 178.5
2791 Male, age 74, right hemisphere 170.7
2458 Female, age 91, both hemispheres 156.7
2081 Male, age 80, both hemispheres 152.7
Medial vestibular nucleus
nTPM: 186.3
2624 Male, age 61, both hemispheres 194.6
2803 Female, age 91, both hemispheres 191.5
2134 Male, age 76, both hemispheres 189.0
2801 Male, age 74, both hemispheres 187.3
2743 Female, age 85, both hemispheres 177.9
2093 Male, age 80, both hemispheres 177.1
Motor facial nucleus
nTPM: 172.6
2062 Male, age 76, both hemispheres 191.6
2365 Male, age 74, right hemisphere 180.5
2795 Female, age 91, both hemispheres 179.2
2697 Female, age 85, both hemispheres 177.2
2126 Male, age 61, both hemispheres 155.7
2327 Male, age 80, both hemispheres 151.2
Motor hypoglossal nucleus
nTPM: 179.8
2461 Male, age 61, both hemispheres 190.7
2182 Male, age 80, both hemispheres 190.2
2132 Female, age 85, both hemispheres 181.8
2125 Female, age 91, both hemispheres 180.1
2277 Male, age 76, both hemispheres 156.4
Motor trigeminal nucleus
nTPM: 166.3
2335 Male, age 61, both hemispheres 183.2
2309 Male, age 76, both hemispheres 167.8
2560 Male, age 74, both hemispheres 164.1
2321 Female, age 91, both hemispheres 160.1
2079 Male, age 80, both hemispheres 156.2
Nuclei of the trapezoid body
nTPM: 172.0
1983 Male, age 76, both hemispheres 187.7
2159 Male, age 61, both hemispheres 187.5
2735 Female, age 85, both hemispheres 172.6
2166 Male, age 80, both hemispheres 156.3
2368 Female, age 91, both hemispheres 156.0
Nucleus ambiguus
nTPM: 169.9
2071 Male, age 76, both hemispheres 176.8
2096 Female, age 85, both hemispheres 162.9
Nucleus cuneatus
nTPM: 167.7
2564 Male, age 74, both hemispheres 191.3
2805 Female, age 91, both hemispheres 172.7
2380 Male, age 80, both hemispheres 167.2
2808 Female, age 85, both hemispheres 165.7
2100 Male, age 76, both hemispheres 155.8
2562 Male, age 61, both hemispheres 153.2
Nucleus gracilis
nTPM: 170.6
2627 Male, age 74, both hemispheres 185.9
2382 Male, age 80, both hemispheres 168.7
2299 Female, age 85, both hemispheres 157.0
Nucleus raphe magnus
nTPM: 174.5
2160 Male, age 61, both hemispheres 195.8
2172 Female, age 85, both hemispheres 179.3
2455 Male, age 74, both hemispheres 176.8
2051 Male, age 76, both hemispheres 176.6
2328 Male, age 80, both hemispheres 164.8
2459 Female, age 91, both hemispheres 153.6
Nucleus raphe obscurus
nTPM: 181.6
2845 Female, age 85, midline 194.6
2800 Male, age 61, midline 176.8
2142 Male, age 76, midline 173.2
Nucleus raphe pallidus
nTPM: 188.1
1924 Male, age 61, midline 199.5
2183 Male, age 80, midline 192.9
2145 Male, age 76, midline 171.8
Nucleus tractus solitarii
nTPM: 168.0
2144 Female, age 91, right hemisphere 189.3
2656 Male, age 76, both hemispheres 166.0
2307 Male, age 80, both hemispheres 162.3
2191 Female, age 85, both hemispheres 154.5
Paramedian reticular nucleus
nTPM: 185.5
2050 Female, age 85, both hemispheres 193.7
2313 Male, age 61, both hemispheres 186.1
2052 Male, age 76, both hemispheres 184.2
2057 Male, age 80, both hemispheres 178.0
Parvicellular reticular nuclei
nTPM: 173.8
2119 Male, age 80, both hemispheres 182.0
2095 Male, age 76, both hemispheres 178.0
2558 Male, age 74, both hemispheres 161.5
Parvicellular reticular nuclei, medullary
nTPM: 176.3
2091 Female, age 85, both hemispheres 183.7
2189 Female, age 91, both hemispheres 178.3
2181 Male, age 80, left hemisphere 166.9
Peritrigeminal nucleus
nTPM: 181.9
2067 Female, age 85, both hemispheres 187.0
2136 Male, age 76, both hemispheres 184.5
2179 Male, age 61, both hemispheres 174.3
Pontine nuclei
nTPM: 176.2
1863 Male, age 55, unknown 198.0
2787 Female, age 85, both hemispheres 188.4
2727 Male, age 61, right hemisphere 186.7
1968 Male, age 76, left hemisphere 178.2
2109 Female, age 72, unknown 178.0
2454 Male, age 74, left hemisphere 164.3
2319 Female, age 91, both hemispheres 164.1
2115 Male, age 80, left hemisphere 152.2
Pontine raphe nucleus
nTPM: 196.9
2853 Male, age 76, midline 209.5
2122 Female, age 85, midline 184.4
Posteroventral cochlear nucleus
nTPM: 171.4
2341 Male, age 80, both hemispheres 177.6
2752 Female, age 85, both hemispheres 173.1
2135 Female, age 91, both hemispheres 172.2
2070 Male, age 76, both hemispheres 172.1
2371 Male, age 61, both hemispheres 162.0
Prepositus hypoglossal nucleus
nTPM: 178.6
2855 Female, age 85, right hemisphere 192.4
2086 Male, age 80, both hemispheres 164.7
Principal sensory trigeminal nucleus
nTPM: 172.5
2158 Male, age 61, both hemispheres 183.6
2324 Male, age 76, both hemispheres 180.5
2367 Female, age 91, left hemisphere 163.2
2008 Male, age 80, left hemisphere 162.9
Reticular pontine nucleus, caudal
nTPM: 166.8
2092 Male, age 76, both hemispheres 182.8
2332 Male, age 80, right hemisphere 167.6
2457 Female, age 91, both hemispheres 159.1
2559 Male, age 74, both hemispheres 157.5
Reticular pontine nucleus, oral
nTPM: 176.1
1939 Male, age 80, both hemispheres 191.9
2012 Female, age 85, both hemispheres 184.7
2167 Male, age 76, both hemispheres 177.5
2366 Female, age 91, both hemispheres 170.5
2361 Male, age 74, both hemispheres 156.1
Reticulotegmental nucleus
nTPM: 178.3
2452 Male, age 74, both hemispheres 186.8
2325 Male, age 76, both hemispheres 184.7
2322 Female, age 91, both hemispheres 171.1
2333 Male, age 80, both hemispheres 170.5
Spinal trigeminal nucleus, caudal
nTPM: 173.2
2390 Female, age 91, both hemispheres 201.4
2447 Male, age 76, both hemispheres 168.2
2312 Male, age 61, both hemispheres 167.2
2642 Male, age 74, both hemispheres 165.4
2308 Male, age 80, both hemispheres 163.7
Spinal trigeminal nucleus, interpolar
nTPM: 187.6
2625 Male, age 61, both hemispheres 211.0
2066 Male, age 76, right hemisphere 195.6
2389 Female, age 91, both hemispheres 181.2
2033 Male, age 80, both hemispheres 181.0
2386 Female, age 85, both hemispheres 169.2
Spinal trigeminal nucleus, oral
nTPM: 168.6
2164 Male, age 80, both hemispheres 180.8
2737 Female, age 85, both hemispheres 166.2
1978 Male, age 76, both hemispheres 158.8
Spinal vestibular nucleus
nTPM: 178.0
2796 Male, age 61, both hemispheres 198.1
2806 Female, age 85, both hemispheres 185.2
2748 Male, age 76, both hemispheres 176.0
2186 Female, age 91, both hemispheres 175.8
2780 Male, age 80, both hemispheres 174.1
2384 Male, age 74, both hemispheres 159.1
Subcoeruleus area
nTPM: 176.2
2369 Female, age 85, left hemisphere 187.1
2323 Female, age 91, left hemisphere 179.9
1958 Male, age 80, both hemispheres 179.1
2451 Male, age 74, both hemispheres 174.8
2089 Male, age 76, left hemisphere 160.0
Superior olive
nTPM: 174.8
1875 Female, age 85, both hemispheres 184.3
2364 Male, age 74, right hemisphere 182.9
2020 Male, age 76, both hemispheres 177.8
2561 Female, age 91, both hemispheres 170.4
2329 Male, age 80, right hemisphere 158.4
Superior vestibular nucleus
nTPM: 174.6
2015 Male, age 80, both hemispheres 179.2
2383 Male, age 74, both hemispheres 172.6
2061 Male, age 76, both hemispheres 171.9
Ventral medullary reticular nucleus
nTPM: 168.3
2060 Male, age 76, both hemispheres 169.6
2372 Male, age 61, both hemispheres 167.0
Ventral periolivary nuclei
nTPM: 169.9
2023 Male, age 76, both hemispheres 183.8
2130 Female, age 85, both hemispheres 171.8
2165 Male, age 80, both hemispheres 171.6
2794 Female, age 91, left hemisphere 152.4
Ventrolateral medulla, A1-C1 cell groups
nTPM: 177.5
1986 Male, age 76, both hemispheres 185.4
2741 Female, age 85, both hemispheres 183.3
2180 Male, age 61, both hemispheres 181.6
2302 Female, age 91, both hemispheres 171.8
2118 Male, age 80, both hemispheres 165.3
Ventrolateral tegmental area, A5 NE cell group
nTPM: 172.2
2840 Female, age 85, both hemispheres 191.0
2359 Male, age 61, both hemispheres 176.7
1959 Male, age 76, both hemispheres 176.2
2449 Male, age 74, both hemispheres 171.7
2161 Male, age 80, both hemispheres 163.7
2456 Female, age 91, both hemispheres 153.9

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1526.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1515.4
FF:10182-103D2 60 years, female 1926.5
FF:10165-103B3 76 years, female 1104.3
Medulla oblongata
Scaled Tags Per Million: 1526.1
FF:10174-103C3 60 years, female 2283.8
FF:10155-103A2 76 years, female 1195.9
FF:10038-101F2 18-64 years, mixed 1098.5
Pons
Scaled Tags Per Million: 1207.1
FF:10033-101E6 18-54 years, mixed 1207.1

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 336.1
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 324.5
Samples: 4

Max nTPM: 356.3
Min nTPM: 294.1
Sample A Female 356.3
Sample B Female 294.1
Sample C Male 307.4
Sample D Male 340.2
Pons
nTPM: 336.1
Samples: 4

Max nTPM: 397.3
Min nTPM: 262.1
Sample A Female 397.3
Sample B Female 262.1
Sample C Male 334.3
Sample D Male 350.8

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 340.3
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 340.4
Samples: 4

Max nTPM: 360.4
Min nTPM: 317.4
Sample A Male 317.4
Sample B Male 359.1
Sample C Female 324.5
Sample D Female 360.4

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.4
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 6.4
69671965 Antisense, RP_050428_02_G01, Mouse strain C57BL/6J (56 days, male) 12.8
70795766 Antisense, RP_050712_01_H11, Mouse strain C57BL/6J (56 days, male) 0.0
Pons
Expression energy: 5.9
69671965 Antisense, RP_050428_02_G01, Mouse strain C57BL/6J (56 days, male) 11.6
70795766 Antisense, RP_050712_01_H11, Mouse strain C57BL/6J (56 days, male) 0.1

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