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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 134.9
Min nTPM: 33.6
Std nTPM: 19.3
Median nTPM:
490_1
67 years, female
134.9
117_1
61 years, male
118.2
89_1
63 years, male
116.9
35_1
74 years, female
113.7
42_1
85 years, male
112.7
491_1
89 years, female
112.0
139_1
64 years, female
111.2
2_1
77 years, female
110.5
6_1
73 years, female
108.3
162_1
79 years, female
105.3
119_1
70 years, female
104.8
4_1
88 years, female
102.3
415_1
77 years, female
102.1
145_1
84 years, male
99.7
142_1
61 years, female
99.6
137_1
83 years, male
98.5
311_1
78 years, male
98.5
17_1
71 years, male
97.8
126_1
63 years, male
97.4
43_1
64 years, female
95.4
495_1
57 years, female
95.0
149_1
88 years, male
93.5
18_1
88 years, male
92.6
501_1
88 years, male
92.4
99_1
64 years, male
92.3
347_1
72 years, male
91.7
115_1
83 years, male
91.5
322_1
76 years, male
90.9
120_1
70 years, female
90.7
32_1
67 years, male
90.6
9_1
66 years, female
90.1
447_1
81 years, male
90.0
375_1
74 years, female
89.4
324_1
76 years, male
89.1
315_1
62 years, female
87.5
109_1
81 years, female
87.4
307_1
66 years, female
87.3
81_1
67 years, male
86.9
313_1
79 years, female
84.4
413_1
59 years, female
83.8
153_1
70 years, female
80.2
266_1
85 years, male
80.2
466_1
57 years, female
79.4
348_1
84 years, male
79.3
217_1
76 years, male
78.1
396_1
62 years, male
77.1
173_1
67 years, male
76.9
41_1
94 years, female
76.1
265_1
87 years, male
76.1
499_1
55 years, female
74.7
316_1
62 years, male
74.2
237_1
82 years, male
74.0
319_1
81 years, male
73.3
379_1
60 years, male
72.5
293_1
68 years, female
71.3
518_1
75 years, female
71.2
480_1
63 years, male
71.1
314_1
67 years, male
71.0
243_1
75 years, male
70.3
288_1
66 years, female
69.1
386_1
76 years, male
67.8
414_1
84 years, female
67.7
506_1
65 years, male
67.4
468_1
89 years, male
67.1
251_1
78 years, male
66.8
526_1
61 years, male
66.4
286_1
68 years, female
65.8
254_1
77 years, female
65.7
350_1
84 years, female
65.2
384_1
83 years, male
65.2
317_1
60 years, male
65.0
404_1
82 years, female
64.8
335_1
73 years, female
64.6
389_1
86 years, female
64.6
406_1
79 years, male
63.9
321_1
62 years, female
63.1
264_1
73 years, female
62.8
356_1
87 years, female
61.6
291_1
76 years, male
61.5
320_1
89 years, female
61.3
351_1
91 years, male
60.6
503_1
68 years, male
60.1
246_1
77 years, male
59.5
318_1
68 years, male
59.4
405_1
91 years, male
58.9
229_1
69 years, female
58.6
517_1
88 years, male
58.5
352_1
62 years, male
58.3
354_1
81 years, female
58.2
353_1
82 years, female
57.8
355_1
70 years, female
57.6
292_1
71 years, male
57.3
377_1
82 years, female
57.1
295_1
61 years, female
56.9
218_1
71 years, female
56.5
189_1
76 years, male
54.9
308_1
70 years, female
53.4
172_1
72 years, female
53.2
376_1
75 years, female
52.6
394_1
75 years, female
52.6
349_1
83 years, male
51.5
452_1
88 years, female
50.9
425_1
59 years, female
50.3
177_1
74 years, male
46.2
163_1
78 years, male
33.6
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
