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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:336.7 nTPM
HPA:336.7 nTPM
GTEx:302.3 nTPM
FANTOM5:491.0 Scaled Tags Per Million
Pig:33.3 nTPM
Mouse:101.0 nTPM
Allen mouse:7.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 336.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 325.0
2019 Male, age 18, unknown 344.9
2666 Male, age 74, left hemisphere 341.4
2586 Male, age 75, left hemisphere 334.8
2411 Female, age 72, unknown 323.7
1827 Male, age 72, unknown 323.4
1830 Male, age 51, unknown 319.0
1833 Male, age 53, unknown 318.2
2828 Female, age 72, unknown 316.9
1870 Female, age 42, unknown 316.1
2219 Male, age 76, both hemispheres 311.4
Dorsal raphe nucleus
nTPM: 316.8
2750 Male, age 76, both hemispheres 331.8
1828 Male, age 53, unknown 324.5
2047 Male, age 72, unknown 311.2
2298 Female, age 72, unknown 308.6
2016 Female, age 72, unknown 307.8
Inferior colliculus
nTPM: 313.4
1890 Male, age 53, unknown 326.3
2097 Female, age 72, unknown 316.7
1848 Female, age 42, unknown 306.3
2849 Male, age 72, unknown 304.1
Median raphe nucleus
nTPM: 328.3
2220 Male, age 76, midline 328.3
Pedunculopontine tegmental nucleus
nTPM: 319.2
2334 Male, age 80, both hemispheres 331.7
1921 Female, age 85, both hemispheres 314.6
2338 Male, age 61, both hemispheres 311.3
Periaquaductal grey, anterior
nTPM: 312.1
2502 Female, age 75, unknown 318.1
1795 Male, age 51, unknown 310.5
1947 Male, age 18, unknown 307.6
Periaquaductal grey, dorsal
nTPM: 313.4
2850 Male, age 76, both hemispheres 331.0
1831 Male, age 72, unknown 320.9
2464 Female, age 72, unknown 309.2
1840 Male, age 53, unknown 292.7
Periaquaductal grey, lateral
nTPM: 310.6
2140 Male, age 76, both hemispheres 319.7
2053 Male, age 18, unknown 307.5
2272 Male, age 74, both hemispheres 304.5
Pretectal area
nTPM: 324.3
2007 Male, age 72, unknown 346.8
1817 Female, age 42, unknown 341.5
1815 Male, age 53, unknown 339.6
1816 Male, age 51, unknown 335.2
1944 Female, age 72, unknown 333.6
2407 Male, age 75, both hemispheres 326.0
2667 Female, age 75, unknown 314.6
2316 Male, age 76, right hemisphere 312.1
2825 Male, age 18, unknown 308.3
2273 Male, age 74, both hemispheres 305.1
2224 Female, age 72, unknown 304.4
Red nucleus
nTPM: 336.7
1904 Male, age 53, unknown 349.9
2785 Male, age 18, unknown 348.0
1865 Male, age 51, unknown 344.4
1821 Female, age 72, unknown 343.8
2503 Female, age 72, unknown 334.8
1954 Female, age 42, unknown 334.3
2588 Male, age 74, left hemisphere 334.3
2227 Male, age 72, unknown 334.1
2769 Male, age 72, unknown 332.3
2823 Male, age 76, right hemisphere 329.8
2725 Female, age 75, unknown 329.4
2584 Male, age 75, left hemisphere 324.9
Substantia nigra
nTPM: 333.5
1916 Female, age 42, unknown 357.9
2409 Female, age 72, unknown 340.2
1851 Male, age 51, unknown 339.2
2699 Male, age 18, unknown 336.0
2583 Male, age 75, right hemisphere 331.4
1889 Female, age 72, unknown 330.5
1941 Male, age 53, unknown 330.1
2665 Male, age 74, both hemispheres 327.1
2590 Female, age 75, unknown 323.4
2241 Male, age 72, unknown 319.4
Superior colliculus
nTPM: 321.7
2668 Female, age 75, unknown 339.5
1913 Female, age 42, unknown 328.2
2087 Female, age 72, unknown 326.8
1995 Male, age 72, unknown 325.9
2587 Male, age 74, left hemisphere 319.5
1796 Male, age 53, unknown 318.3
2261 Male, age 18, unknown 316.7
2664 Male, age 75, both hemispheres 315.9
1839 Male, age 51, unknown 313.4
1895 Male, age 76, right hemisphere 312.6
Ventral tegmental area
nTPM: 323.8
2410 Female, age 72, unknown 336.9
2223 Female, age 72, unknown 331.0
1915 Female, age 42, unknown 325.9
2218 Male, age 76, both hemispheres 319.3
1942 Male, age 51, unknown 315.9
2021 Male, age 53, unknown 314.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 302.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 302.3
Samples: 139

Max nTPM: 616.3
Min nTPM: 160.5
Std nTPM: 89.6
Median nTPM: 272.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 616.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 594.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 567.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 540.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 536.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 516.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 512.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 489.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 487.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 481.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 475.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 474.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 453.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 412.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 402.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 402.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 400.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 396.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 392.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 390.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 388.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 378.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 370.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 369.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 368.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 363.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 361.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 357.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 354.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 349.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 348.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 347.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 347.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 345.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 342.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 340.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 339.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 337.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 337.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 332.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 332.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 328.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 325.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 324.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 324.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 324.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 323.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 323.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 318.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 318.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 318.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 317.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 312.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 310.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 308.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 304.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 303.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 297.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 293.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 291.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 286.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 286.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 285.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 285.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 280.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 280.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 278.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 277.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 274.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 272.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 269.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 267.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 267.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 265.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 265.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 265.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 262.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 260.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 260.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 260.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 259.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 258.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 258.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 258.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 257.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 254.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 254.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 253.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 252.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 252.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 251.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 251.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 251.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 249.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 249.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 249.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 247.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 247.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 247.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 246.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 246.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 246.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 244.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 244.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 243.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 242.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 241.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 240.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 237.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 237.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 236.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 235.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 235.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 234.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 234.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 230.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 229.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 228.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 225.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 221.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 220.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 219.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 219.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 216.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 216.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 214.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 213.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 212.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 211.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 205.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 204.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 203.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 200.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 199.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 197.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 191.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 181.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 174.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 160.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 491.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 491.0
FF:10158-103A5 76 years, female 491.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 33.3
Pig sample Sample description nTPM
Midbrain
nTPM: 33.4
Samples: 4

Max nTPM: 46.9
Min nTPM: 26.5
Sample A Female 46.9
Sample B Female 26.5
Sample C Male 30.6
Sample D Male 29.4
Periaqueductal gray
nTPM: 24.3
Samples: 3

Max nTPM: 26.5
Min nTPM: 23.1
Sample B Female 23.3
Sample C Male 26.5
Sample D Male 23.1
Substantia nigra
nTPM: 30.9
Samples: 4

Max nTPM: 33.8
Min nTPM: 27.2
Sample A Female 33.8
Sample B Female 27.2
Sample C Male 30.8
Sample D Male 31.6
Superior colliculi
nTPM: 33.2
Samples: 4

Max nTPM: 39.5
Min nTPM: 25.9
Sample A Female 39.5
Sample B Female 25.9
Sample C Male 33.9
Sample D Male 33.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 101.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 101.0
Samples: 4

Max nTPM: 106.8
Min nTPM: 95.1
Sample A Male 106.8
Sample B Male 101.7
Sample C Female 95.1
Sample D Female 100.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.0
69288650 Antisense, RP_050407_01_D10, Mouse strain C57BL/6J (56 days, male) 7.0

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