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  • ATP1B2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:395.1 nTPM
HPA:395.1 nTPM
GTEx:223.8 nTPM
FANTOM5:583.6 Scaled Tags Per Million
Pig:582.6 nTPM
Mouse:480.1 nTPM
Allen mouse:17.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 395.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 229.8
2586 Male, age 75, left hemisphere 383.8
2828 Female, age 72, unknown 292.8
1833 Male, age 53, unknown 268.2
1827 Male, age 72, unknown 236.6
2219 Male, age 76, both hemispheres 218.6
2666 Male, age 74, left hemisphere 211.5
1830 Male, age 51, unknown 208.5
1870 Female, age 42, unknown 182.9
2411 Female, age 72, unknown 179.4
2019 Male, age 18, unknown 115.3
Dorsal raphe nucleus
nTPM: 290.8
2047 Male, age 72, unknown 389.4
1828 Male, age 53, unknown 375.5
2016 Female, age 72, unknown 276.0
2298 Female, age 72, unknown 220.9
2750 Male, age 76, both hemispheres 192.1
Inferior colliculus
nTPM: 395.1
2849 Male, age 72, unknown 456.1
1848 Female, age 42, unknown 436.5
1890 Male, age 53, unknown 352.8
2097 Female, age 72, unknown 335.2
Median raphe nucleus
nTPM: 220.5
2220 Male, age 76, midline 220.5
Pedunculopontine tegmental nucleus
nTPM: 244.3
2334 Male, age 80, both hemispheres 258.9
1921 Female, age 85, both hemispheres 251.1
2338 Male, age 61, both hemispheres 223.0
Periaquaductal grey, anterior
nTPM: 237.5
2502 Female, age 75, unknown 251.2
1947 Male, age 18, unknown 247.6
1795 Male, age 51, unknown 213.6
Periaquaductal grey, dorsal
nTPM: 296.4
2850 Male, age 76, both hemispheres 375.5
1840 Male, age 53, unknown 302.1
2464 Female, age 72, unknown 292.1
1831 Male, age 72, unknown 216.0
Periaquaductal grey, lateral
nTPM: 266.7
2140 Male, age 76, both hemispheres 340.7
2053 Male, age 18, unknown 288.1
2272 Male, age 74, both hemispheres 171.3
Pretectal area
nTPM: 231.3
2825 Male, age 18, unknown 321.6
1817 Female, age 42, unknown 311.8
1944 Female, age 72, unknown 272.9
2667 Female, age 75, unknown 260.2
1816 Male, age 51, unknown 255.4
2224 Female, age 72, unknown 217.0
2316 Male, age 76, right hemisphere 189.4
2273 Male, age 74, both hemispheres 188.7
1815 Male, age 53, unknown 188.3
2007 Male, age 72, unknown 175.5
2407 Male, age 75, both hemispheres 163.3
Red nucleus
nTPM: 270.5
1954 Female, age 42, unknown 349.4
2823 Male, age 76, right hemisphere 341.1
2725 Female, age 75, unknown 332.5
2503 Female, age 72, unknown 314.3
2227 Male, age 72, unknown 291.0
1821 Female, age 72, unknown 286.1
2769 Male, age 72, unknown 285.3
1865 Male, age 51, unknown 258.1
2588 Male, age 74, left hemisphere 255.0
1904 Male, age 53, unknown 240.2
2584 Male, age 75, left hemisphere 174.0
2785 Male, age 18, unknown 119.3
Substantia nigra
nTPM: 258.6
2699 Male, age 18, unknown 474.7
1916 Female, age 42, unknown 328.8
1889 Female, age 72, unknown 269.7
1941 Male, age 53, unknown 249.6
2665 Male, age 74, both hemispheres 244.1
1851 Male, age 51, unknown 218.6
2241 Male, age 72, unknown 217.3
2409 Female, age 72, unknown 205.8
2583 Male, age 75, right hemisphere 191.8
2590 Female, age 75, unknown 185.4
Superior colliculus
nTPM: 222.5
2087 Female, age 72, unknown 277.6
2664 Male, age 75, both hemispheres 268.2
1839 Male, age 51, unknown 262.8
2261 Male, age 18, unknown 261.7
1895 Male, age 76, right hemisphere 213.1
1796 Male, age 53, unknown 212.3
1995 Male, age 72, unknown 203.4
2668 Female, age 75, unknown 187.9
2587 Male, age 74, left hemisphere 173.5
1913 Female, age 42, unknown 164.8
Ventral tegmental area
nTPM: 214.0
2218 Male, age 76, both hemispheres 262.5
2410 Female, age 72, unknown 227.6
1942 Male, age 51, unknown 213.4
1915 Female, age 42, unknown 211.4
2021 Male, age 53, unknown 187.5
2223 Female, age 72, unknown 181.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 223.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 223.8
Samples: 139

Max nTPM: 968.5
Min nTPM: 25.2
Std nTPM: 158.0
Median nTPM: 196.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 968.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 808.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 758.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 730.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 727.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 599.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 573.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 490.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 485.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 472.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 468.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 456.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 426.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 405.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 389.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 353.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 352.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 349.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 348.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 342.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 340.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 337.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 335.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 329.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 324.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 312.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 307.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 302.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 302.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 294.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 290.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 283.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 279.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 274.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 273.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 269.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 266.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 264.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 257.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 250.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 249.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 245.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 242.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 242.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 234.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 231.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 229.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 224.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 220.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 220.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 220.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 219.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 219.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 219.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 218.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 217.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 215.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 213.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 212.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 211.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 209.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 208.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 206.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 203.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 203.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 202.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 201.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 198.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 198.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 196.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 193.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 192.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 187.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 185.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 184.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 176.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 176.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 173.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 172.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 171.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 163.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 163.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 162.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 159.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 156.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 155.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 154.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 154.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 153.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 153.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 153.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 152.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 145.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 145.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 144.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 137.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 136.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 135.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 134.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 134.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 125.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 123.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 122.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 117.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 116.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 114.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 111.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 110.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 108.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 108.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 107.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 107.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 105.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 100.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 100.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 100.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 99.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 94.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 91.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 88.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 86.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 86.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 86.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 82.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 79.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 75.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 74.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 68.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 65.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 61.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 59.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 58.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 54.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 53.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 50.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 50.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 32.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 25.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 583.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 583.6
FF:10158-103A5 76 years, female 583.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 582.6
Pig sample Sample description nTPM
Midbrain
nTPM: 523.1
Samples: 4

Max nTPM: 708.0
Min nTPM: 329.6
Sample A Female 329.6
Sample B Female 457.2
Sample C Male 708.0
Sample D Male 597.4
Periaqueductal gray
nTPM: 404.3
Samples: 3

Max nTPM: 446.6
Min nTPM: 329.6
Sample B Female 436.6
Sample C Male 446.6
Sample D Male 329.6
Substantia nigra
nTPM: 489.7
Samples: 4

Max nTPM: 660.9
Min nTPM: 300.0
Sample A Female 473.3
Sample B Female 300.0
Sample C Male 524.5
Sample D Male 660.9
Superior colliculi
nTPM: 582.6
Samples: 4

Max nTPM: 815.9
Min nTPM: 317.5
Sample A Female 815.9
Sample B Female 317.5
Sample C Male 560.1
Sample D Male 636.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 480.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 480.1
Samples: 4

Max nTPM: 517.1
Min nTPM: 458.4
Sample A Male 458.4
Sample B Male 461.5
Sample C Female 517.1
Sample D Female 483.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 17.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.3
74819255 Antisense, RP_060315_02_D07, Mouse strain C57BL/6J (56 days, male) 17.5
68744958 Antisense, RP_050210_01_A04, Mouse strain C57BL/6J (56 days, male) 17.1

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