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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 134.7
Min nTPM: 9.1
Std nTPM: 28.6
Median nTPM:
353_1
82 years, female
134.7
352_1
62 years, male
119.7
351_1
91 years, male
116.9
163_1
78 years, male
115.9
350_1
84 years, female
114.6
218_1
71 years, female
111.6
172_1
72 years, female
106.5
452_1
88 years, female
104.1
349_1
83 years, male
99.3
177_1
74 years, male
98.5
386_1
76 years, male
96.2
319_1
81 years, male
96.1
320_1
89 years, female
95.9
506_1
65 years, male
95.3
243_1
75 years, male
95.2
356_1
87 years, female
93.9
321_1
62 years, female
93.8
354_1
81 years, female
93.8
335_1
73 years, female
89.0
425_1
59 years, female
86.3
295_1
61 years, female
86.2
318_1
68 years, male
84.9
292_1
71 years, male
83.3
316_1
62 years, male
80.3
173_1
67 years, male
79.8
293_1
68 years, female
79.5
406_1
79 years, male
79.5
355_1
70 years, female
79.1
376_1
75 years, female
78.7
447_1
81 years, male
76.4
286_1
68 years, female
76.1
322_1
76 years, male
74.9
251_1
78 years, male
72.1
405_1
91 years, male
71.9
347_1
72 years, male
69.9
503_1
68 years, male
69.9
237_1
82 years, male
69.8
348_1
84 years, male
68.7
291_1
76 years, male
68.5
229_1
69 years, female
68.3
480_1
63 years, male
63.7
317_1
60 years, male
63.4
379_1
60 years, male
62.6
377_1
82 years, female
61.8
264_1
73 years, female
60.8
404_1
82 years, female
60.1
99_1
64 years, male
59.8
517_1
88 years, male
59.8
189_1
76 years, male
58.7
394_1
75 years, female
58.4
6_1
73 years, female
56.7
396_1
62 years, male
54.4
384_1
83 years, male
53.0
375_1
74 years, female
52.8
389_1
86 years, female
52.5
526_1
61 years, male
51.3
518_1
75 years, female
50.9
311_1
78 years, male
50.3
324_1
76 years, male
49.5
254_1
77 years, female
49.4
145_1
84 years, male
48.2
266_1
85 years, male
48.0
314_1
67 years, male
47.2
115_1
83 years, male
46.7
265_1
87 years, male
46.2
468_1
89 years, male
46.2
137_1
83 years, male
45.2
41_1
94 years, female
45.1
18_1
88 years, male
45.0
246_1
77 years, male
43.8
217_1
76 years, male
43.1
288_1
66 years, female
42.7
17_1
71 years, male
37.9
9_1
66 years, female
36.5
153_1
70 years, female
36.3
81_1
67 years, male
35.3
35_1
74 years, female
35.1
313_1
79 years, female
34.1
109_1
81 years, female
34.0
32_1
67 years, male
33.4
499_1
55 years, female
32.7
117_1
61 years, male
32.0
120_1
70 years, female
30.8
43_1
64 years, female
29.4
126_1
63 years, male
29.0
139_1
64 years, female
28.9
2_1
77 years, female
28.4
315_1
62 years, female
28.4
495_1
57 years, female
28.0
307_1
66 years, female
27.8
4_1
88 years, female
26.1
501_1
88 years, male
25.3
142_1
61 years, female
25.1
415_1
77 years, female
24.7
42_1
85 years, male
24.0
466_1
57 years, female
23.3
414_1
84 years, female
20.7
162_1
79 years, female
20.6
119_1
70 years, female
20.1
308_1
70 years, female
19.8
149_1
88 years, male
18.1
89_1
63 years, male
17.3
413_1
59 years, female
16.1
490_1
67 years, female
15.0
491_1
89 years, female
9.1
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
