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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:94.6 nTPM
HPA:94.6 nTPM
GTEx:118.7 nTPM
FANTOM5:121.6 Scaled Tags Per Million
Pig:114.0 nTPM
Mouse:84.7 nTPM
Allen mouse:11.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 94.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 91.3
1870 Female, age 42, unknown 93.3
2586 Male, age 75, left hemisphere 92.7
2019 Male, age 18, unknown 92.6
2666 Male, age 74, left hemisphere 91.7
1830 Male, age 51, unknown 91.5
2411 Female, age 72, unknown 91.1
2828 Female, age 72, unknown 90.9
1827 Male, age 72, unknown 90.4
1833 Male, age 53, unknown 90.4
2219 Male, age 76, both hemispheres 89.0
Dorsal raphe nucleus
nTPM: 91.4
2750 Male, age 76, both hemispheres 96.3
2298 Female, age 72, unknown 92.5
1828 Male, age 53, unknown 90.9
2047 Male, age 72, unknown 89.1
2016 Female, age 72, unknown 88.0
Inferior colliculus
nTPM: 87.4
2849 Male, age 72, unknown 88.3
2097 Female, age 72, unknown 87.7
1890 Male, age 53, unknown 87.1
1848 Female, age 42, unknown 86.7
Median raphe nucleus
nTPM: 94.6
2220 Male, age 76, midline 94.6
Pedunculopontine tegmental nucleus
nTPM: 92.9
2338 Male, age 61, both hemispheres 97.2
2334 Male, age 80, both hemispheres 94.0
1921 Female, age 85, both hemispheres 87.4
Periaquaductal grey, anterior
nTPM: 92.8
2502 Female, age 75, unknown 95.7
1947 Male, age 18, unknown 91.5
1795 Male, age 51, unknown 91.2
Periaquaductal grey, dorsal
nTPM: 87.3
1831 Male, age 72, unknown 88.4
2850 Male, age 76, both hemispheres 87.7
2464 Female, age 72, unknown 87.4
1840 Male, age 53, unknown 85.8
Periaquaductal grey, lateral
nTPM: 89.3
2272 Male, age 74, both hemispheres 94.8
2140 Male, age 76, both hemispheres 86.8
2053 Male, age 18, unknown 86.5
Pretectal area
nTPM: 90.1
1815 Male, age 53, unknown 92.0
2407 Male, age 75, both hemispheres 91.9
1817 Female, age 42, unknown 91.7
2007 Male, age 72, unknown 91.2
1944 Female, age 72, unknown 90.6
2273 Male, age 74, both hemispheres 89.8
1816 Male, age 51, unknown 89.7
2667 Female, age 75, unknown 89.5
2224 Female, age 72, unknown 89.2
2825 Male, age 18, unknown 88.7
2316 Male, age 76, right hemisphere 87.0
Red nucleus
nTPM: 94.3
2503 Female, age 72, unknown 98.0
1904 Male, age 53, unknown 97.1
2227 Male, age 72, unknown 95.9
1865 Male, age 51, unknown 95.8
1821 Female, age 72, unknown 95.4
2785 Male, age 18, unknown 95.2
2769 Male, age 72, unknown 94.4
2584 Male, age 75, left hemisphere 92.9
2588 Male, age 74, left hemisphere 92.8
2725 Female, age 75, unknown 92.5
1954 Female, age 42, unknown 92.2
2823 Male, age 76, right hemisphere 89.5
Substantia nigra
nTPM: 93.3
1916 Female, age 42, unknown 100.8
2699 Male, age 18, unknown 99.6
1851 Male, age 51, unknown 97.3
2665 Male, age 74, both hemispheres 96.5
1941 Male, age 53, unknown 94.9
2590 Female, age 75, unknown 92.4
1889 Female, age 72, unknown 91.1
2583 Male, age 75, right hemisphere 89.3
2241 Male, age 72, unknown 88.7
2409 Female, age 72, unknown 82.2
Superior colliculus
nTPM: 91.5
2587 Male, age 74, left hemisphere 95.8
1913 Female, age 42, unknown 95.1
1796 Male, age 53, unknown 94.0
1995 Male, age 72, unknown 94.0
2668 Female, age 75, unknown 91.4
2664 Male, age 75, both hemispheres 89.9
1839 Male, age 51, unknown 89.7
2087 Female, age 72, unknown 89.3
2261 Male, age 18, unknown 89.1
1895 Male, age 76, right hemisphere 86.7
Ventral tegmental area
nTPM: 93.9
1915 Female, age 42, unknown 97.5
2218 Male, age 76, both hemispheres 97.0
2410 Female, age 72, unknown 94.9
2223 Female, age 72, unknown 94.0
1942 Male, age 51, unknown 91.7
2021 Male, age 53, unknown 88.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 118.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 118.7
Samples: 139

Max nTPM: 220.0
Min nTPM: 55.9
Std nTPM: 26.5
Median nTPM: 115.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 220.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 210.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 209.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 177.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 175.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 171.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 170.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 169.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 166.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 165.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 163.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 158.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 158.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 157.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 156.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 154.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 152.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 149.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 146.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 140.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 136.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 135.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 135.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 135.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 135.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 135.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 134.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 132.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 132.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 132.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 132.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 131.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 131.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 131.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 131.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 129.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 127.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 127.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 127.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 126.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 126.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 126.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 126.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 126.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 126.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 126.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 125.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 125.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 124.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 124.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 124.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 122.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 122.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 121.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 121.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 120.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 120.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 119.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 119.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 118.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 118.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 118.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 118.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 118.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 118.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 117.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 117.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 116.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 116.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 115.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 115.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 115.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 114.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 113.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 112.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 112.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 111.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 110.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 110.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 110.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 109.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 109.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 109.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 109.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 108.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 107.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 107.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 106.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 106.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 106.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 105.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 105.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 104.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 102.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 102.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 102.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 101.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 101.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 101.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 100.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 100.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 100.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 100.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 100.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 100.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 100.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 100.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 99.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 99.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 99.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 98.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 98.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 98.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 97.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 97.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 97.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 96.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 96.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 96.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 96.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 95.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 94.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 94.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 93.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 91.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 91.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 91.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 90.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 90.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 90.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 88.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 87.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 85.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 82.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 82.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 80.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 78.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 62.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 55.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 121.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 121.6
FF:10158-103A5 76 years, female 121.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 114.0
Pig sample Sample description nTPM
Midbrain
nTPM: 114.0
Samples: 4

Max nTPM: 175.3
Min nTPM: 83.5
Sample A Female 175.3
Sample B Female 108.7
Sample C Male 83.5
Sample D Male 88.4
Periaqueductal gray
nTPM: 89.2
Samples: 3

Max nTPM: 95.8
Min nTPM: 82.9
Sample B Female 88.9
Sample C Male 95.8
Sample D Male 82.9
Substantia nigra
nTPM: 111.8
Samples: 4

Max nTPM: 141.5
Min nTPM: 97.0
Sample A Female 141.5
Sample B Female 97.0
Sample C Male 99.8
Sample D Male 108.8
Superior colliculi
nTPM: 112.6
Samples: 4

Max nTPM: 140.4
Min nTPM: 102.0
Sample A Female 140.4
Sample B Female 104.7
Sample C Male 103.1
Sample D Male 102.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 84.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 84.7
Samples: 4

Max nTPM: 92.1
Min nTPM: 76.5
Sample A Male 92.1
Sample B Male 83.4
Sample C Female 76.5
Sample D Female 86.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 11.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.3
293259 Antisense, RP_040617_01_A06, Mouse strain C57BL/6J (56 days, male) 12.7
81599612 Antisense, RP_071126_01_B12, Mouse strain C57BL/6J (56 days, male) 9.9

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