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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:24.7 nTPM
HPA:24.7 nTPM
GTEx:433.7 nTPM
FANTOM5:37.5 Scaled Tags Per Million
Pig:670.2 nTPM
Mouse:2132.5 nTPM
Allen mouse:26.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 24.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 6.2
2219 Male, age 76, both hemispheres 62.1
1827 Male, age 72, unknown 0.0
1830 Male, age 51, unknown 0.0
1833 Male, age 53, unknown 0.0
1870 Female, age 42, unknown 0.0
2019 Male, age 18, unknown 0.0
2411 Female, age 72, unknown 0.0
2586 Male, age 75, left hemisphere 0.0
2666 Male, age 74, left hemisphere 0.0
2828 Female, age 72, unknown 0.0
Dorsal raphe nucleus
nTPM: 0.0
1828 Male, age 53, unknown 0.0
2016 Female, age 72, unknown 0.0
2047 Male, age 72, unknown 0.0
2298 Female, age 72, unknown 0.0
2750 Male, age 76, both hemispheres 0.0
Inferior colliculus
nTPM: 12.3
2097 Female, age 72, unknown 49.3
1848 Female, age 42, unknown 0.0
1890 Male, age 53, unknown 0.0
2849 Male, age 72, unknown 0.0
Median raphe nucleus
nTPM: 0.0
2220 Male, age 76, midline 0.0
Pedunculopontine tegmental nucleus
nTPM: 7.9
2338 Male, age 61, both hemispheres 23.9
1921 Female, age 85, both hemispheres 0.0
2334 Male, age 80, both hemispheres 0.0
Periaquaductal grey, anterior
nTPM: 0.0
1795 Male, age 51, unknown 0.0
1947 Male, age 18, unknown 0.0
2502 Female, age 75, unknown 0.0
Periaquaductal grey, dorsal
nTPM: 0.0
1831 Male, age 72, unknown 0.0
1840 Male, age 53, unknown 0.0
2464 Female, age 72, unknown 0.0
2850 Male, age 76, both hemispheres 0.0
Periaquaductal grey, lateral
nTPM: 0.0
2053 Male, age 18, unknown 0.0
2140 Male, age 76, both hemispheres 0.0
2272 Male, age 74, both hemispheres 0.0
Pretectal area
nTPM: 22.8
1817 Female, age 42, unknown 67.6
1944 Female, age 72, unknown 67.0
2007 Male, age 72, unknown 58.8
1816 Male, age 51, unknown 57.8
1815 Male, age 53, unknown 0.0
2224 Female, age 72, unknown 0.0
2273 Male, age 74, both hemispheres 0.0
2316 Male, age 76, right hemisphere 0.0
2407 Male, age 75, both hemispheres 0.0
2667 Female, age 75, unknown 0.0
2825 Male, age 18, unknown 0.0
Red nucleus
nTPM: 0.0
1821 Female, age 72, unknown 0.0
1865 Male, age 51, unknown 0.0
1904 Male, age 53, unknown 0.0
1954 Female, age 42, unknown 0.0
2227 Male, age 72, unknown 0.0
2503 Female, age 72, unknown 0.0
2584 Male, age 75, left hemisphere 0.0
2588 Male, age 74, left hemisphere 0.0
2725 Female, age 75, unknown 0.0
2769 Male, age 72, unknown 0.0
2785 Male, age 18, unknown 0.0
2823 Male, age 76, right hemisphere 0.0
Substantia nigra
nTPM: 24.7
1941 Male, age 53, unknown 160.2
1889 Female, age 72, unknown 58.5
1916 Female, age 42, unknown 28.8
1851 Male, age 51, unknown 0.0
2241 Male, age 72, unknown 0.0
2409 Female, age 72, unknown 0.0
2583 Male, age 75, right hemisphere 0.0
2590 Female, age 75, unknown 0.0
2665 Male, age 74, both hemispheres 0.0
2699 Male, age 18, unknown 0.0
Superior colliculus
nTPM: 7.5
2668 Female, age 75, unknown 34.8
1895 Male, age 76, right hemisphere 22.3
2087 Female, age 72, unknown 18.1
1796 Male, age 53, unknown 0.0
1839 Male, age 51, unknown 0.0
1913 Female, age 42, unknown 0.0
1995 Male, age 72, unknown 0.0
2261 Male, age 18, unknown 0.0
2587 Male, age 74, left hemisphere 0.0
2664 Male, age 75, both hemispheres 0.0
Ventral tegmental area
nTPM: 3.8
2218 Male, age 76, both hemispheres 23.3
1915 Female, age 42, unknown 0.0
1942 Male, age 51, unknown 0.0
2021 Male, age 53, unknown 0.0
2223 Female, age 72, unknown 0.0
2410 Female, age 72, unknown 0.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 433.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 433.7
Samples: 139

Max nTPM: 4659.2
Min nTPM: 10.6
Std nTPM: 578.3
Median nTPM: 243.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 4659.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 3142.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 2428.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1535.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1515.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 1424.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1252.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1223.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1152.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1096.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1052.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1017.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 974.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 943.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 901.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 897.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 896.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 821.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 812.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 797.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 795.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 791.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 788.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 763.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 747.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 737.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 725.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 718.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 687.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 658.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 631.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 615.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 602.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 585.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 583.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 570.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 568.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 553.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 545.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 529.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 527.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 521.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 489.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 487.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 484.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 479.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 476.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 464.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 461.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 440.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 430.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 409.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 400.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 393.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 393.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 380.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 378.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 377.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 357.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 356.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 342.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 341.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 327.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 316.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 314.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 272.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 263.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 250.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 248.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 243.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 243.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 234.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 212.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 204.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 191.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 188.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 188.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 183.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 182.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 167.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 161.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 158.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 156.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 152.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 151.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 142.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 140.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 137.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 133.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 132.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 131.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 130.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 127.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 123.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 121.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 118.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 115.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 115.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 104.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 103.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 96.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 94.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 91.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 90.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 89.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 85.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 84.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 83.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 79.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 78.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 78.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 74.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 72.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 69.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 65.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 65.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 64.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 62.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 61.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 58.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 58.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 57.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 55.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 54.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 48.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 45.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 40.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 37.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 37.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 35.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 32.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 32.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 30.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 30.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 22.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 16.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 15.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 10.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 37.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 37.5
FF:10158-103A5 76 years, female 37.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 670.2
Pig sample Sample description nTPM
Midbrain
nTPM: 509.4
Samples: 4

Max nTPM: 766.5
Min nTPM: 205.6
Sample A Female 205.6
Sample B Female 300.1
Sample C Male 766.5
Sample D Male 765.3
Periaqueductal gray
nTPM: 279.1
Samples: 3

Max nTPM: 327.5
Min nTPM: 236.8
Sample B Female 273.1
Sample C Male 327.5
Sample D Male 236.8
Substantia nigra
nTPM: 367.4
Samples: 4

Max nTPM: 588.4
Min nTPM: 130.4
Sample A Female 588.4
Sample B Female 250.6
Sample C Male 500.0
Sample D Male 130.4
Superior colliculi
nTPM: 670.2
Samples: 4

Max nTPM: 934.1
Min nTPM: 305.1
Sample A Female 776.0
Sample B Female 305.1
Sample C Male 934.1
Sample D Male 665.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 2132.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 2132.5
Samples: 4

Max nTPM: 2228.6
Min nTPM: 2042.6
Sample A Male 2095.3
Sample B Male 2228.6
Sample C Female 2163.6
Sample D Female 2042.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 26.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 26.4
70919418 Antisense, RP_050713_01_C08, Mouse strain C57BL/6J (56 days, male) 26.4

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