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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:203.8 nTPM
HPA:203.8 nTPM
GTEx:240.8 nTPM
FANTOM5:377.6 Scaled Tags Per Million
Pig:406.4 nTPM
Mouse:448.3 nTPM
Allen mouse:1.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 203.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 192.6
2411 Female, age 72, unknown 218.3
1870 Female, age 42, unknown 209.2
1833 Male, age 53, unknown 194.9
2019 Male, age 18, unknown 194.2
1830 Male, age 51, unknown 186.9
1827 Male, age 72, unknown 186.1
2666 Male, age 74, left hemisphere 186.0
2828 Female, age 72, unknown 185.8
2219 Male, age 76, both hemispheres 183.1
2586 Male, age 75, left hemisphere 181.4
Dorsal raphe nucleus
nTPM: 188.5
2750 Male, age 76, both hemispheres 209.2
2298 Female, age 72, unknown 196.2
2047 Male, age 72, unknown 184.1
1828 Male, age 53, unknown 176.8
2016 Female, age 72, unknown 176.2
Inferior colliculus
nTPM: 179.6
2097 Female, age 72, unknown 198.9
1890 Male, age 53, unknown 179.0
1848 Female, age 42, unknown 175.3
2849 Male, age 72, unknown 165.4
Median raphe nucleus
nTPM: 192.9
2220 Male, age 76, midline 192.9
Pedunculopontine tegmental nucleus
nTPM: 191.8
2334 Male, age 80, both hemispheres 210.4
1921 Female, age 85, both hemispheres 192.2
2338 Male, age 61, both hemispheres 172.8
Periaquaductal grey, anterior
nTPM: 193.3
1947 Male, age 18, unknown 201.4
2502 Female, age 75, unknown 189.4
1795 Male, age 51, unknown 189.0
Periaquaductal grey, dorsal
nTPM: 171.0
2464 Female, age 72, unknown 176.8
1831 Male, age 72, unknown 174.8
2850 Male, age 76, both hemispheres 169.0
1840 Male, age 53, unknown 163.7
Periaquaductal grey, lateral
nTPM: 170.5
2053 Male, age 18, unknown 181.1
2272 Male, age 74, both hemispheres 175.9
2140 Male, age 76, both hemispheres 154.6
Pretectal area
nTPM: 189.2
1815 Male, age 53, unknown 212.7
2007 Male, age 72, unknown 205.7
1817 Female, age 42, unknown 202.3
1816 Male, age 51, unknown 198.0
1944 Female, age 72, unknown 191.5
2224 Female, age 72, unknown 185.5
2667 Female, age 75, unknown 183.4
2825 Male, age 18, unknown 179.9
2273 Male, age 74, both hemispheres 177.8
2316 Male, age 76, right hemisphere 172.8
2407 Male, age 75, both hemispheres 171.9
Red nucleus
nTPM: 203.8
1821 Female, age 72, unknown 226.2
1904 Male, age 53, unknown 222.8
2503 Female, age 72, unknown 218.5
1954 Female, age 42, unknown 214.8
1865 Male, age 51, unknown 207.4
2785 Male, age 18, unknown 203.5
2725 Female, age 75, unknown 199.5
2823 Male, age 76, right hemisphere 197.4
2588 Male, age 74, left hemisphere 194.4
2769 Male, age 72, unknown 194.4
2227 Male, age 72, unknown 193.1
2584 Male, age 75, left hemisphere 173.1
Substantia nigra
nTPM: 190.5
2241 Male, age 72, unknown 207.7
1889 Female, age 72, unknown 201.0
2409 Female, age 72, unknown 200.5
1851 Male, age 51, unknown 198.5
2590 Female, age 75, unknown 193.0
1941 Male, age 53, unknown 189.1
2583 Male, age 75, right hemisphere 188.7
1916 Female, age 42, unknown 188.5
2699 Male, age 18, unknown 173.6
2665 Male, age 74, both hemispheres 164.3
Superior colliculus
nTPM: 188.1
1913 Female, age 42, unknown 203.6
2587 Male, age 74, left hemisphere 198.4
2668 Female, age 75, unknown 196.7
1995 Male, age 72, unknown 193.2
2261 Male, age 18, unknown 190.5
1895 Male, age 76, right hemisphere 186.2
1839 Male, age 51, unknown 182.0
1796 Male, age 53, unknown 181.6
2087 Female, age 72, unknown 180.8
2664 Male, age 75, both hemispheres 167.5
Ventral tegmental area
nTPM: 191.2
2410 Female, age 72, unknown 211.1
1915 Female, age 42, unknown 193.2
2218 Male, age 76, both hemispheres 191.4
2223 Female, age 72, unknown 189.5
1942 Male, age 51, unknown 184.3
2021 Male, age 53, unknown 177.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 240.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 240.8
Samples: 139

Max nTPM: 403.5
Min nTPM: 135.1
Std nTPM: 52.5
Median nTPM: 236.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 403.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 399.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 397.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 392.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 366.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 346.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 340.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 327.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 325.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 318.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 313.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 308.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 307.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 306.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 305.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 305.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 304.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 298.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 298.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 297.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 295.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 294.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 293.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 287.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 282.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 282.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 279.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 279.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 277.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 277.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 277.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 275.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 275.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 274.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 272.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 271.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 271.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 266.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 265.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 265.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 264.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 264.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 263.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 262.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 260.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 259.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 257.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 255.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 254.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 254.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 253.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 253.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 253.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 251.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 247.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 247.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 247.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 246.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 245.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 244.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 244.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 243.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 242.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 240.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 240.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 239.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 239.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 239.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 237.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 236.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 234.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 231.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 230.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 228.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 227.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 226.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 226.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 226.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 224.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 223.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 223.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 222.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 221.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 221.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 219.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 219.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 219.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 217.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 217.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 216.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 214.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 213.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 213.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 213.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 212.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 212.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 211.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 211.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 209.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 207.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 206.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 205.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 204.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 199.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 199.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 198.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 197.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 197.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 197.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 196.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 193.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 193.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 191.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 191.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 191.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 190.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 189.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 188.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 188.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 187.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 186.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 185.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 181.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 181.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 180.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 180.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 178.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 176.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 175.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 174.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 174.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 173.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 168.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 166.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 161.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 159.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 156.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 154.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 135.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 377.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 377.6
FF:10158-103A5 76 years, female 377.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 406.4
Pig sample Sample description nTPM
Midbrain
nTPM: 406.4
Samples: 4

Max nTPM: 593.2
Min nTPM: 325.8
Sample A Female 593.2
Sample B Female 380.4
Sample C Male 325.8
Sample D Male 326.1
Periaqueductal gray
nTPM: 294.6
Samples: 3

Max nTPM: 308.9
Min nTPM: 271.0
Sample B Female 308.9
Sample C Male 304.0
Sample D Male 271.0
Substantia nigra
nTPM: 388.6
Samples: 4

Max nTPM: 501.6
Min nTPM: 282.0
Sample A Female 501.6
Sample B Female 282.0
Sample C Male 407.2
Sample D Male 363.4
Superior colliculi
nTPM: 364.3
Samples: 4

Max nTPM: 432.5
Min nTPM: 261.0
Sample A Female 432.5
Sample B Female 261.0
Sample C Male 406.6
Sample D Male 357.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 448.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 448.3
Samples: 4

Max nTPM: 457.3
Min nTPM: 439.7
Sample A Male 452.2
Sample B Male 439.7
Sample C Female 444.0
Sample D Female 457.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.4
1131 Antisense, RP_Baylor_103129, Mouse strain C57BL/6J (56 days, male) 5.5
1130 Antisense, RP_Baylor_103129, Mouse strain C57BL/6J (56 days, male) 4.7
70566163 Antisense, RP_050628_02_D11, Mouse strain C57BL/6J (56 days, male) 0.1
73931419 Antisense, RP_051214_04_E11, Mouse strain C57BL/6J (56 days, male) 0.0
1132 Sense, RPS_Baylor_37069, Mouse strain C57BL/6J (56 days, male) 0.0

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