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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:604.6 nTPM
HPA:604.6 nTPM
GTEx:631.0 nTPM
FANTOM5:713.1 Scaled Tags Per Million
Pig:95.2 nTPM
Mouse:522.1 nTPM
Allen mouse:4.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 604.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 555.6
2411 Female, age 72, unknown 582.1
1827 Male, age 72, unknown 575.8
1870 Female, age 42, unknown 562.5
2019 Male, age 18, unknown 562.1
2219 Male, age 76, both hemispheres 560.7
2828 Female, age 72, unknown 557.7
1833 Male, age 53, unknown 551.2
2666 Male, age 74, left hemisphere 548.0
1830 Male, age 51, unknown 545.7
2586 Male, age 75, left hemisphere 510.7
Dorsal raphe nucleus
nTPM: 586.9
2298 Female, age 72, unknown 614.5
2047 Male, age 72, unknown 597.2
2750 Male, age 76, both hemispheres 585.9
1828 Male, age 53, unknown 584.3
2016 Female, age 72, unknown 552.7
Inferior colliculus
nTPM: 548.2
2097 Female, age 72, unknown 559.6
1890 Male, age 53, unknown 547.1
1848 Female, age 42, unknown 545.9
2849 Male, age 72, unknown 540.4
Median raphe nucleus
nTPM: 604.6
2220 Male, age 76, midline 604.6
Pedunculopontine tegmental nucleus
nTPM: 590.6
2334 Male, age 80, both hemispheres 606.5
1921 Female, age 85, both hemispheres 585.7
2338 Male, age 61, both hemispheres 579.6
Periaquaductal grey, anterior
nTPM: 558.8
1947 Male, age 18, unknown 578.4
1795 Male, age 51, unknown 555.1
2502 Female, age 75, unknown 543.0
Periaquaductal grey, dorsal
nTPM: 547.6
2850 Male, age 76, both hemispheres 566.4
1840 Male, age 53, unknown 552.8
2464 Female, age 72, unknown 541.3
1831 Male, age 72, unknown 530.0
Periaquaductal grey, lateral
nTPM: 551.6
2272 Male, age 74, both hemispheres 559.0
2140 Male, age 76, both hemispheres 550.5
2053 Male, age 18, unknown 545.5
Pretectal area
nTPM: 569.7
1817 Female, age 42, unknown 588.9
1816 Male, age 51, unknown 585.9
1944 Female, age 72, unknown 583.0
2667 Female, age 75, unknown 583.0
2007 Male, age 72, unknown 579.0
2273 Male, age 74, both hemispheres 575.3
2224 Female, age 72, unknown 569.1
1815 Male, age 53, unknown 566.6
2825 Male, age 18, unknown 554.5
2407 Male, age 75, both hemispheres 546.6
2316 Male, age 76, right hemisphere 534.2
Red nucleus
nTPM: 560.1
1821 Female, age 72, unknown 608.6
2725 Female, age 75, unknown 592.7
1954 Female, age 42, unknown 573.5
2823 Male, age 76, right hemisphere 564.0
1865 Male, age 51, unknown 560.5
2503 Female, age 72, unknown 558.5
1904 Male, age 53, unknown 553.7
2769 Male, age 72, unknown 553.2
2785 Male, age 18, unknown 551.9
2227 Male, age 72, unknown 549.5
2588 Male, age 74, left hemisphere 529.2
2584 Male, age 75, left hemisphere 526.1
Substantia nigra
nTPM: 603.8
1916 Female, age 42, unknown 665.4
2241 Male, age 72, unknown 646.7
1941 Male, age 53, unknown 635.4
1851 Male, age 51, unknown 625.9
1889 Female, age 72, unknown 606.9
2409 Female, age 72, unknown 602.1
2699 Male, age 18, unknown 599.2
2665 Male, age 74, both hemispheres 562.9
2590 Female, age 75, unknown 557.3
2583 Male, age 75, right hemisphere 536.1
Superior colliculus
nTPM: 549.2
2587 Male, age 74, left hemisphere 574.8
1895 Male, age 76, right hemisphere 565.2
1796 Male, age 53, unknown 560.1
2087 Female, age 72, unknown 559.1
2668 Female, age 75, unknown 556.6
2261 Male, age 18, unknown 547.7
1839 Male, age 51, unknown 539.9
1913 Female, age 42, unknown 537.0
2664 Male, age 75, both hemispheres 526.7
1995 Male, age 72, unknown 524.9
Ventral tegmental area
nTPM: 589.3
2410 Female, age 72, unknown 617.9
1915 Female, age 42, unknown 616.7
2218 Male, age 76, both hemispheres 609.8
2223 Female, age 72, unknown 569.9
1942 Male, age 51, unknown 569.4
2021 Male, age 53, unknown 552.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 631.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 631.0
Samples: 139

Max nTPM: 1342.6
Min nTPM: 296.4
Std nTPM: 180.4
Median nTPM: 582.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1342.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1198.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1173.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1128.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1046.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1036.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 963.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 948.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 947.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 942.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 935.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 899.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 898.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 887.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 879.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 874.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 865.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 845.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 834.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 830.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 830.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 821.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 802.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 796.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 786.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 785.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 777.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 755.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 745.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 741.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 732.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 730.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 722.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 722.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 718.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 715.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 715.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 711.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 701.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 695.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 688.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 683.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 677.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 671.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 671.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 652.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 650.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 647.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 646.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 644.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 642.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 641.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 636.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 632.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 631.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 627.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 625.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 624.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 622.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 621.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 619.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 618.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 608.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 593.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 592.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 591.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 589.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 588.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 585.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 582.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 577.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 576.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 571.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 571.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 570.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 568.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 565.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 558.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 558.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 554.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 552.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 551.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 545.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 544.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 543.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 542.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 541.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 536.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 530.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 530.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 530.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 529.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 527.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 526.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 526.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 524.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 521.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 520.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 517.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 516.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 514.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 513.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 510.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 510.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 509.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 505.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 504.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 502.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 501.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 501.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 500.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 499.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 497.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 491.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 490.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 487.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 485.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 481.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 474.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 474.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 474.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 473.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 470.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 469.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 464.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 457.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 443.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 442.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 434.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 428.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 426.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 422.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 415.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 414.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 397.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 377.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 376.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 343.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 296.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 713.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 713.1
FF:10158-103A5 76 years, female 713.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 95.2
Pig sample Sample description nTPM
Midbrain
nTPM: 95.2
Samples: 4

Max nTPM: 109.7
Min nTPM: 83.1
Sample A Female 109.7
Sample B Female 90.3
Sample C Male 97.6
Sample D Male 83.1
Periaqueductal gray
nTPM: 74.9
Samples: 3

Max nTPM: 87.5
Min nTPM: 67.3
Sample B Female 70.0
Sample C Male 87.5
Sample D Male 67.3
Substantia nigra
nTPM: 93.8
Samples: 4

Max nTPM: 132.4
Min nTPM: 64.4
Sample A Female 132.4
Sample B Female 70.9
Sample C Male 107.6
Sample D Male 64.4
Superior colliculi
nTPM: 95.2
Samples: 4

Max nTPM: 111.7
Min nTPM: 69.9
Sample A Female 111.0
Sample B Female 69.9
Sample C Male 111.7
Sample D Male 88.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 522.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 522.1
Samples: 4

Max nTPM: 552.3
Min nTPM: 491.5
Sample A Male 552.3
Sample B Male 519.0
Sample C Female 491.5
Sample D Female 525.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.0
79587726 Antisense, RP_071204_02_D06, Mouse strain C57BL/6J (56 days, male) 10.4
79749602 Antisense, RP_071204_02_D06, Mouse strain C57BL/6J (56 days, male) 6.4
994 Antisense, RP_Baylor_103044, Mouse strain C57BL/6J (56 days, male) 1.6
993 Sense, RPS_Baylor_37046, Mouse strain C57BL/6J (56 days, male) 0.0

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