We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
ANK2
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • METABOLIC
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • METABOLIC

  • ANK2
BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

Read more
103.312
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:119.5 nTPM
HPA:119.5 nTPM
FANTOM5:464.4 Scaled Tags Per Million
Pig:164.6 nTPM
Allen mouse:14.7 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

Read more
, antibody CAB015178
Pons mean intensity 103.312
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

Read more
FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 17.799
Parabrachial nucleus 83.079
Principle sensory trigeminal nucleus 30.557
Locus coeruleus 80.949
Pontine nucleus 28.683
Vestibular nucleus 15.507
Pontine reticular nucleus, oral 8.740
Lateral lemniscus 7.664
Superior paraolivary nucleus 27.821

PONS - HPA Brain RNA-seq
Max nTPM 119.5
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 31.4
1984 Male, age 76, both hemispheres 53.4
2188 Female, age 91, both hemispheres 44.7
2301 Female, age 85, both hemispheres 20.1
2090 Male, age 80, both hemispheres 7.3
Dorsal cochlear nucleus
nTPM: 17.9
2058 Male, age 76, both hemispheres 38.9
2370 Male, age 61, both hemispheres 22.6
2187 Female, age 91, both hemispheres 20.0
2802 Male, age 74, right hemisphere 7.9
2378 Male, age 80, both hemispheres 0.0
Dorsal tegmental nucleus
nTPM: 30.9
2083 Male, age 80, both hemispheres 54.5
1936 Male, age 76, left hemisphere 38.0
2326 Male, age 74, both hemispheres 24.0
2358 Male, age 61, both hemispheres 7.2
Dorsolateral tegmental area
nTPM: 32.8
2751 Female, age 85, both hemispheres 44.9
2654 Male, age 80, both hemispheres 43.9
2360 Male, age 74, both hemispheres 42.6
2141 Male, age 76, both hemispheres 32.5
2337 Male, age 61, both hemispheres 0.0
Kolliker-Fuse nucleus
nTPM: 51.9
2163 Male, age 80, both hemispheres 75.7
2793 Female, age 91, left hemisphere 56.9
2315 Male, age 76, right hemisphere 23.2
Lateral lemniscal nuclei
nTPM: 102.3
2169 Male, age 76, both hemispheres 162.2
2036 Male, age 80, both hemispheres 114.3
2453 Male, age 74, right hemisphere 98.0
2746 Female, age 85, left hemisphere 91.1
2320 Female, age 91, left hemisphere 45.9
Lateral parabrachial nucleus
nTPM: 62.8
2139 Female, age 85, right hemisphere 133.0
2013 Male, age 80, both hemispheres 55.9
2790 Male, age 61, both hemispheres 43.7
2792 Male, age 76, both hemispheres 18.5
Lateral vestibular nucleus
nTPM: 44.0
2184 Male, age 76, both hemispheres 66.9
2311 Male, age 80, both hemispheres 21.1
Locus coeruleus
nTPM: 93.8
2014 Male, age 55, unknown 131.7
2788 Male, age 74, unknown 121.0
2123 Female, age 91, both hemispheres 99.3
2720 Male, age 74, both hemispheres 91.5
2317 Female, age 72, unknown 80.8
2162 Male, age 80, both hemispheres 67.3
1980 Male, age 76, both hemispheres 64.9
Medial olivary nucleus
nTPM: 18.4
2138 Female, age 91, both hemispheres 37.0
1943 Male, age 61, both hemispheres 20.2
2851 Male, age 80, both hemispheres 16.2
1962 Male, age 76, both hemispheres 0.0
Medial parabrachial nucleus
nTPM: 43.0
2854 Male, age 80, both hemispheres 72.0
2463 Female, age 85, right hemisphere 40.8
2156 Male, age 61, both hemispheres 40.5
2786 Male, age 76, both hemispheres 36.5
2170 Female, age 91, both hemispheres 25.2
Medial periolivary nuclei
nTPM: 96.3
2171 Female, age 85, both hemispheres 173.5
2063 Male, age 76, both hemispheres 152.8
2791 Male, age 74, right hemisphere 84.4
2081 Male, age 80, both hemispheres 35.6
2458 Female, age 91, both hemispheres 35.3
Motor facial nucleus
nTPM: 92.0
2062 Male, age 76, both hemispheres 165.1
2697 Female, age 85, both hemispheres 94.2
2365 Male, age 74, right hemisphere 93.8
2327 Male, age 80, both hemispheres 85.7
2795 Female, age 91, both hemispheres 64.3
2126 Male, age 61, both hemispheres 48.9
Motor trigeminal nucleus
nTPM: 47.8
2079 Male, age 80, both hemispheres 95.5
2560 Male, age 74, both hemispheres 52.0
2309 Male, age 76, both hemispheres 49.3
2335 Male, age 61, both hemispheres 22.8
2321 Female, age 91, both hemispheres 19.4
Nuclei of the trapezoid body
nTPM: 119.5
2159 Male, age 61, both hemispheres 177.5
2735 Female, age 85, both hemispheres 147.0
1983 Male, age 76, both hemispheres 138.2
2166 Male, age 80, both hemispheres 77.6
2368 Female, age 91, both hemispheres 56.9
Paramedian reticular nucleus
nTPM: 74.2
2050 Female, age 85, both hemispheres 128.9
2057 Male, age 80, both hemispheres 59.0
2313 Male, age 61, both hemispheres 57.6
2052 Male, age 76, both hemispheres 51.4
Pontine nuclei
nTPM: 116.3
2727 Male, age 61, right hemisphere 188.5
2787 Female, age 85, both hemispheres 186.9
1863 Male, age 55, unknown 166.1
1968 Male, age 76, left hemisphere 125.7
2109 Female, age 72, unknown 113.4
2454 Male, age 74, left hemisphere 61.1
2115 Male, age 80, left hemisphere 47.5
2319 Female, age 91, both hemispheres 41.1
Pontine raphe nucleus
nTPM: 74.9
2122 Female, age 85, midline 110.1
2853 Male, age 76, midline 39.8
Posteroventral cochlear nucleus
nTPM: 34.1
2752 Female, age 85, both hemispheres 78.3
2070 Male, age 76, both hemispheres 47.8
2341 Male, age 80, both hemispheres 16.0
2135 Female, age 91, both hemispheres 15.9
2371 Male, age 61, both hemispheres 12.6
Principal sensory trigeminal nucleus
nTPM: 99.8
2158 Male, age 61, both hemispheres 178.6
2008 Male, age 80, left hemisphere 127.4
2367 Female, age 91, left hemisphere 46.9
2324 Male, age 76, both hemispheres 46.4
Reticular pontine nucleus, caudal
nTPM: 69.5
2092 Male, age 76, both hemispheres 104.8
2332 Male, age 80, right hemisphere 95.3
2457 Female, age 91, both hemispheres 50.0
2559 Male, age 74, both hemispheres 27.9
Reticular pontine nucleus, oral
nTPM: 68.4
2012 Female, age 85, both hemispheres 99.6
2361 Male, age 74, both hemispheres 71.7
2366 Female, age 91, both hemispheres 66.5
1939 Male, age 80, both hemispheres 57.7
2167 Male, age 76, both hemispheres 46.6
Reticulotegmental nucleus
nTPM: 47.4
2325 Male, age 76, both hemispheres 89.6
2333 Male, age 80, both hemispheres 44.9
2322 Female, age 91, both hemispheres 31.8
2452 Male, age 74, both hemispheres 23.5
Spinal trigeminal nucleus, oral
nTPM: 46.6
2737 Female, age 85, both hemispheres 60.0
2164 Male, age 80, both hemispheres 43.0
1978 Male, age 76, both hemispheres 36.9
Subcoeruleus area
nTPM: 56.0
1958 Male, age 80, both hemispheres 97.0
2089 Male, age 76, left hemisphere 95.2
2323 Female, age 91, left hemisphere 47.6
2369 Female, age 85, left hemisphere 30.7
2451 Male, age 74, both hemispheres 9.4
Superior olive
nTPM: 89.1
1875 Female, age 85, both hemispheres 150.2
2020 Male, age 76, both hemispheres 101.3
2364 Male, age 74, right hemisphere 76.6
2329 Male, age 80, right hemisphere 67.8
2561 Female, age 91, both hemispheres 49.3
Superior vestibular nucleus
nTPM: 44.7
2383 Male, age 74, both hemispheres 62.8
2015 Male, age 80, both hemispheres 43.4
2061 Male, age 76, both hemispheres 27.8
Ventral periolivary nuclei
nTPM: 105.5
2130 Female, age 85, both hemispheres 140.9
2165 Male, age 80, both hemispheres 128.3
2023 Male, age 76, both hemispheres 92.6
2794 Female, age 91, left hemisphere 60.3
Ventrolateral tegmental area, A5 NE cell group
nTPM: 71.1
1959 Male, age 76, both hemispheres 113.6
2449 Male, age 74, both hemispheres 105.0
2840 Female, age 85, both hemispheres 76.7
2161 Male, age 80, both hemispheres 68.2
2359 Male, age 61, both hemispheres 39.5
2456 Female, age 91, both hemispheres 23.6

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 464.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 270.5
FF:10182-103D2 60 years, female 277.3
FF:10165-103B3 76 years, female 263.7
Pons
Scaled Tags Per Million: 464.4
FF:10033-101E6 18-54 years, mixed 464.4

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 164.6
Pig sample Sample description nTPM
Pons
nTPM: 164.6
Samples: 4

Max nTPM: 193.4
Min nTPM: 133.9
Sample A Female 193.4
Sample B Female 133.9
Sample C Male 149.1
Sample D Male 182.0

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.7
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 14.7
68844707 Antisense, RP_050222_02_C04, Mouse strain C57BL/6J (56 days, male) 16.8
71924087 Antisense, RP_051017_02_H10, Mouse strain C57BL/6J (56 days, male) 12.6

Contact

  • NEWS ARTICLES
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.