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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:205.0 nTPM
HPA:205.0 nTPM
FANTOM5:264.9 Scaled Tags Per Million
Pig:95.9 nTPM
Allen mouse:7.3 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 205.0
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 171.5
2090 Male, age 80, both hemispheres 195.4
2301 Female, age 85, both hemispheres 188.5
2188 Female, age 91, both hemispheres 178.2
1984 Male, age 76, both hemispheres 124.1
Dorsal cochlear nucleus
nTPM: 184.3
2378 Male, age 80, both hemispheres 213.6
2802 Male, age 74, right hemisphere 204.8
2058 Male, age 76, both hemispheres 178.4
2370 Male, age 61, both hemispheres 163.2
2187 Female, age 91, both hemispheres 161.6
Dorsal tegmental nucleus
nTPM: 156.1
2083 Male, age 80, both hemispheres 176.7
2326 Male, age 74, both hemispheres 173.5
1936 Male, age 76, left hemisphere 169.1
2358 Male, age 61, both hemispheres 105.2
Dorsolateral tegmental area
nTPM: 148.2
2654 Male, age 80, both hemispheres 179.7
2751 Female, age 85, both hemispheres 167.8
2360 Male, age 74, both hemispheres 139.5
2141 Male, age 76, both hemispheres 136.6
2337 Male, age 61, both hemispheres 117.4
Kolliker-Fuse nucleus
nTPM: 167.4
2793 Female, age 91, left hemisphere 177.0
2315 Male, age 76, right hemisphere 173.4
2163 Male, age 80, both hemispheres 151.7
Lateral lemniscal nuclei
nTPM: 137.7
2320 Female, age 91, left hemisphere 158.2
2169 Male, age 76, both hemispheres 142.2
2746 Female, age 85, left hemisphere 136.6
2036 Male, age 80, both hemispheres 128.4
2453 Male, age 74, right hemisphere 123.2
Lateral parabrachial nucleus
nTPM: 166.9
2792 Male, age 76, both hemispheres 209.7
2013 Male, age 80, both hemispheres 177.5
2139 Female, age 85, right hemisphere 162.4
2790 Male, age 61, both hemispheres 117.8
Lateral vestibular nucleus
nTPM: 178.0
2311 Male, age 80, both hemispheres 186.8
2184 Male, age 76, both hemispheres 169.2
Locus coeruleus
nTPM: 128.3
2162 Male, age 80, both hemispheres 140.0
2720 Male, age 74, both hemispheres 137.6
2317 Female, age 72, unknown 133.4
2788 Male, age 74, unknown 128.7
2123 Female, age 91, both hemispheres 121.1
1980 Male, age 76, both hemispheres 120.6
2014 Male, age 55, unknown 117.0
Medial olivary nucleus
nTPM: 205.0
2138 Female, age 91, both hemispheres 227.0
1943 Male, age 61, both hemispheres 226.3
2851 Male, age 80, both hemispheres 191.5
1962 Male, age 76, both hemispheres 175.1
Medial parabrachial nucleus
nTPM: 152.8
2786 Male, age 76, both hemispheres 173.4
2463 Female, age 85, right hemisphere 158.2
2170 Female, age 91, both hemispheres 155.5
2854 Male, age 80, both hemispheres 147.2
2156 Male, age 61, both hemispheres 129.9
Medial periolivary nuclei
nTPM: 142.4
2081 Male, age 80, both hemispheres 153.9
2458 Female, age 91, both hemispheres 152.6
2063 Male, age 76, both hemispheres 149.4
2791 Male, age 74, right hemisphere 140.4
2171 Female, age 85, both hemispheres 115.8
Motor facial nucleus
nTPM: 153.4
2126 Male, age 61, both hemispheres 176.0
2697 Female, age 85, both hemispheres 164.4
2795 Female, age 91, both hemispheres 162.3
2062 Male, age 76, both hemispheres 145.4
2327 Male, age 80, both hemispheres 138.8
2365 Male, age 74, right hemisphere 133.7
Motor trigeminal nucleus
nTPM: 153.5
2309 Male, age 76, both hemispheres 187.8
2321 Female, age 91, both hemispheres 158.7
2335 Male, age 61, both hemispheres 147.0
2560 Male, age 74, both hemispheres 140.4
2079 Male, age 80, both hemispheres 133.6
Nuclei of the trapezoid body
nTPM: 145.9
2166 Male, age 80, both hemispheres 169.9
2368 Female, age 91, both hemispheres 154.2
2159 Male, age 61, both hemispheres 148.3
1983 Male, age 76, both hemispheres 145.3
2735 Female, age 85, both hemispheres 112.0
Paramedian reticular nucleus
nTPM: 151.0
2057 Male, age 80, both hemispheres 168.6
2052 Male, age 76, both hemispheres 153.1
2313 Male, age 61, both hemispheres 150.4
2050 Female, age 85, both hemispheres 132.0
Pontine nuclei
nTPM: 141.7
2319 Female, age 91, both hemispheres 168.0
2115 Male, age 80, left hemisphere 158.3
1968 Male, age 76, left hemisphere 158.1
2109 Female, age 72, unknown 147.9
1863 Male, age 55, unknown 143.1
2454 Male, age 74, left hemisphere 137.8
2787 Female, age 85, both hemispheres 112.9
2727 Male, age 61, right hemisphere 107.5
Pontine raphe nucleus
nTPM: 141.4
2853 Male, age 76, midline 153.9
2122 Female, age 85, midline 129.0
Posteroventral cochlear nucleus
nTPM: 183.8
2135 Female, age 91, both hemispheres 209.6
2341 Male, age 80, both hemispheres 199.9
2371 Male, age 61, both hemispheres 190.6
2070 Male, age 76, both hemispheres 167.3
2752 Female, age 85, both hemispheres 151.5
Principal sensory trigeminal nucleus
nTPM: 146.0
2324 Male, age 76, both hemispheres 176.5
2367 Female, age 91, left hemisphere 154.1
2158 Male, age 61, both hemispheres 130.9
2008 Male, age 80, left hemisphere 122.7
Reticular pontine nucleus, caudal
nTPM: 153.0
2092 Male, age 76, both hemispheres 170.8
2457 Female, age 91, both hemispheres 158.2
2559 Male, age 74, both hemispheres 157.3
2332 Male, age 80, right hemisphere 125.8
Reticular pontine nucleus, oral
nTPM: 156.3
2366 Female, age 91, both hemispheres 181.1
2167 Male, age 76, both hemispheres 175.0
1939 Male, age 80, both hemispheres 162.2
2012 Female, age 85, both hemispheres 143.0
2361 Male, age 74, both hemispheres 120.2
Reticulotegmental nucleus
nTPM: 154.5
2452 Male, age 74, both hemispheres 162.3
2333 Male, age 80, both hemispheres 156.3
2322 Female, age 91, both hemispheres 153.8
2325 Male, age 76, both hemispheres 145.4
Spinal trigeminal nucleus, oral
nTPM: 146.9
1978 Male, age 76, both hemispheres 156.2
2164 Male, age 80, both hemispheres 151.6
2737 Female, age 85, both hemispheres 132.9
Subcoeruleus area
nTPM: 157.5
2369 Female, age 85, left hemisphere 183.2
2451 Male, age 74, both hemispheres 168.5
2089 Male, age 76, left hemisphere 152.9
1958 Male, age 80, both hemispheres 142.5
2323 Female, age 91, left hemisphere 140.3
Superior olive
nTPM: 150.3
2020 Male, age 76, both hemispheres 175.9
2329 Male, age 80, right hemisphere 157.9
2561 Female, age 91, both hemispheres 153.5
2364 Male, age 74, right hemisphere 138.9
1875 Female, age 85, both hemispheres 125.4
Superior vestibular nucleus
nTPM: 165.8
2015 Male, age 80, both hemispheres 173.4
2061 Male, age 76, both hemispheres 170.6
2383 Male, age 74, both hemispheres 153.3
Ventral periolivary nuclei
nTPM: 146.1
2023 Male, age 76, both hemispheres 170.6
2165 Male, age 80, both hemispheres 145.5
2794 Female, age 91, left hemisphere 136.6
2130 Female, age 85, both hemispheres 131.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 149.1
2456 Female, age 91, both hemispheres 167.3
1959 Male, age 76, both hemispheres 162.9
2161 Male, age 80, both hemispheres 151.6
2840 Female, age 85, both hemispheres 148.3
2359 Male, age 61, both hemispheres 137.6
2449 Male, age 74, both hemispheres 127.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 264.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 264.9
FF:10182-103D2 60 years, female 320.6
FF:10165-103B3 76 years, female 209.2
Pons
Scaled Tags Per Million: 224.0
FF:10033-101E6 18-54 years, mixed 224.0

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 95.9
Pig sample Sample description nTPM
Pons
nTPM: 95.9
Samples: 4

Max nTPM: 130.1
Min nTPM: 80.4
Sample A Female 83.6
Sample B Female 80.4
Sample C Male 89.4
Sample D Male 130.1

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.3
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 7.3
74511880 Antisense, RP_051121_04_A01, Mouse strain C57BL/6J (56 days, male) 9.9
68667288 Antisense, RP_050201_02_A02, Mouse strain C57BL/6J (56 days, male) 4.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.