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EIF4A2
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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:290.2 nTPM
HPA:290.2 nTPM
FANTOM5:830.5 Scaled Tags Per Million
Pig:557.5 nTPM
Mouse:877.7 nTPM
Allen mouse:15.6 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 290.2
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 232.8
2188 Female, age 91, both hemispheres 240.5
1984 Male, age 76, both hemispheres 238.6
2090 Male, age 80, both hemispheres 231.4
2301 Female, age 85, both hemispheres 220.7
Area postrema
nTPM: 213.3
2799 Male, age 61, both hemispheres 219.0
2306 Male, age 80, both hemispheres 214.2
2054 Male, age 76, both hemispheres 206.7
Cuneate nuclei
nTPM: 224.5
2376 Male, age 61, both hemispheres 234.1
2381 Male, age 80, both hemispheres 220.2
2131 Male, age 76, both hemispheres 219.1
Dorsal cochlear nucleus
nTPM: 233.1
2187 Female, age 91, both hemispheres 250.5
2802 Male, age 74, right hemisphere 245.8
2370 Male, age 61, both hemispheres 225.3
2058 Male, age 76, both hemispheres 222.2
2378 Male, age 80, both hemispheres 221.7
Dorsal medullary reticular nucleus
nTPM: 235.9
2040 Female, age 85, both hemispheres 269.2
2373 Male, age 61, both hemispheres 227.2
2088 Male, age 76, both hemispheres 211.2
Dorsal motor vagal complex
nTPM: 225.9
2133 Female, age 91, both hemispheres 263.7
2000 Male, age 74, unknown 242.1
2844 Male, age 55, unknown 237.9
2813 Female, age 72, unknown 237.7
2643 Male, age 74, both hemispheres 221.7
2797 Male, age 61, both hemispheres 207.7
2185 Male, age 76, both hemispheres 199.2
2807 Female, age 85, both hemispheres 196.8
Dorsal tegmental nucleus
nTPM: 236.7
2326 Male, age 74, both hemispheres 255.2
2083 Male, age 80, both hemispheres 253.3
1936 Male, age 76, left hemisphere 221.6
2358 Male, age 61, both hemispheres 216.5
Dorsolateral tegmental area
nTPM: 242.7
2751 Female, age 85, both hemispheres 257.8
2654 Male, age 80, both hemispheres 250.5
2360 Male, age 74, both hemispheres 242.0
2141 Male, age 76, both hemispheres 234.5
2337 Male, age 61, both hemispheres 228.8
Gigantocellular reticular nuclei, medullary
nTPM: 248.4
2462 Male, age 74, both hemispheres 265.8
1876 Female, age 85, both hemispheres 264.4
2022 Male, age 76, right hemisphere 257.1
2314 Male, age 61, both hemispheres 239.1
2387 Female, age 91, both hemispheres 236.0
2310 Male, age 80, both hemispheres 227.9
Gigantocellular reticular nuclei, pars
nTPM: 240.8
2168 Male, age 76, both hemispheres 293.4
2084 Female, age 85, both hemispheres 248.8
2336 Male, age 61, both hemispheres 232.8
2706 Male, age 80, both hemispheres 215.7
2330 Male, age 80, both hemispheres 213.6
Inferior olive
nTPM: 227.6
2563 Male, age 74, both hemispheres 244.3
2178 Male, age 61, both hemispheres 238.5
2628 Female, age 91, both hemispheres 223.0
2085 Female, age 85, both hemispheres 216.4
2379 Male, age 80, both hemispheres 215.8
Kolliker-Fuse nucleus
nTPM: 247.3
2163 Male, age 80, both hemispheres 257.3
2315 Male, age 76, right hemisphere 249.6
2793 Female, age 91, left hemisphere 235.0
Lateral lemniscal nuclei
nTPM: 266.3
2169 Male, age 76, both hemispheres 313.7
2746 Female, age 85, left hemisphere 289.1
2036 Male, age 80, both hemispheres 254.3
2453 Male, age 74, right hemisphere 248.1
2320 Female, age 91, left hemisphere 226.4
Lateral medullary reticular nucleus
nTPM: 237.1
2044 Male, age 76, both hemispheres 259.6
2305 Male, age 74, both hemispheres 247.8
2804 Female, age 91, both hemispheres 235.6
2374 Male, age 61, both hemispheres 232.6
2190 Female, age 85, both hemispheres 228.2
2852 Male, age 80, both hemispheres 218.9
Lateral parabrachial nucleus
nTPM: 246.2
2139 Female, age 85, right hemisphere 292.4
2013 Male, age 80, both hemispheres 249.9
2792 Male, age 76, both hemispheres 222.1
2790 Male, age 61, both hemispheres 220.5
Lateral vestibular nucleus
nTPM: 237.2
2311 Male, age 80, both hemispheres 237.2
2184 Male, age 76, both hemispheres 237.1
Locus coeruleus
nTPM: 256.5
2123 Female, age 91, both hemispheres 279.5
2788 Male, age 74, unknown 269.8
2014 Male, age 55, unknown 268.9
2720 Male, age 74, both hemispheres 266.0
2317 Female, age 72, unknown 242.8
2162 Male, age 80, both hemispheres 239.6
1980 Male, age 76, both hemispheres 229.2
Medial olivary nucleus
nTPM: 235.9
1943 Male, age 61, both hemispheres 254.4
2138 Female, age 91, both hemispheres 237.6
1962 Male, age 76, both hemispheres 227.2
2851 Male, age 80, both hemispheres 224.5
Medial parabrachial nucleus
nTPM: 244.9
2170 Female, age 91, both hemispheres 275.9
2854 Male, age 80, both hemispheres 257.9
2463 Female, age 85, right hemisphere 233.0
2786 Male, age 76, both hemispheres 232.6
2156 Male, age 61, both hemispheres 225.0
Medial periolivary nuclei
nTPM: 267.7
2063 Male, age 76, both hemispheres 318.6
2171 Female, age 85, both hemispheres 313.6
2791 Male, age 74, right hemisphere 262.1
2081 Male, age 80, both hemispheres 224.4
2458 Female, age 91, both hemispheres 219.7
Medial vestibular nucleus
nTPM: 255.4
2803 Female, age 91, both hemispheres 278.5
2801 Male, age 74, both hemispheres 267.2
2743 Female, age 85, both hemispheres 254.8
2093 Male, age 80, both hemispheres 253.5
2134 Male, age 76, both hemispheres 248.5
2624 Male, age 61, both hemispheres 230.2
Motor facial nucleus
nTPM: 256.7
2062 Male, age 76, both hemispheres 313.2
2365 Male, age 74, right hemisphere 273.6
2697 Female, age 85, both hemispheres 253.3
2795 Female, age 91, both hemispheres 243.7
2126 Male, age 61, both hemispheres 231.3
2327 Male, age 80, both hemispheres 225.1
Motor hypoglossal nucleus
nTPM: 236.1
2125 Female, age 91, both hemispheres 268.4
2132 Female, age 85, both hemispheres 254.2
2461 Male, age 61, both hemispheres 232.7
2182 Male, age 80, both hemispheres 221.2
2277 Male, age 76, both hemispheres 203.8
Motor trigeminal nucleus
nTPM: 233.9
2079 Male, age 80, both hemispheres 246.0
2309 Male, age 76, both hemispheres 241.3
2560 Male, age 74, both hemispheres 233.5
2335 Male, age 61, both hemispheres 229.5
2321 Female, age 91, both hemispheres 219.1
Nuclei of the trapezoid body
nTPM: 273.1
1983 Male, age 76, both hemispheres 331.2
2735 Female, age 85, both hemispheres 311.1
2159 Male, age 61, both hemispheres 274.0
2166 Male, age 80, both hemispheres 234.4
2368 Female, age 91, both hemispheres 214.8
Nucleus ambiguus
nTPM: 218.8
2096 Female, age 85, both hemispheres 221.4
2071 Male, age 76, both hemispheres 216.2
Nucleus cuneatus
nTPM: 213.6
2564 Male, age 74, both hemispheres 232.0
2562 Male, age 61, both hemispheres 218.3
2380 Male, age 80, both hemispheres 217.8
2805 Female, age 91, both hemispheres 210.0
2100 Male, age 76, both hemispheres 202.9
2808 Female, age 85, both hemispheres 200.4
Nucleus gracilis
nTPM: 218.4
2627 Male, age 74, both hemispheres 248.8
2382 Male, age 80, both hemispheres 214.2
2299 Female, age 85, both hemispheres 192.1
Nucleus raphe magnus
nTPM: 275.4
2160 Male, age 61, both hemispheres 328.0
2172 Female, age 85, both hemispheres 312.7
2455 Male, age 74, both hemispheres 288.6
2051 Male, age 76, both hemispheres 260.8
2328 Male, age 80, both hemispheres 234.2
2459 Female, age 91, both hemispheres 228.3
Nucleus raphe obscurus
nTPM: 232.9
2845 Female, age 85, midline 250.3
2800 Male, age 61, midline 245.7
2142 Male, age 76, midline 202.7
Nucleus raphe pallidus
nTPM: 244.3
1924 Male, age 61, midline 275.0
2183 Male, age 80, midline 251.9
2145 Male, age 76, midline 206.1
Nucleus tractus solitarii
nTPM: 228.4
2144 Female, age 91, right hemisphere 288.5
2656 Male, age 76, both hemispheres 218.4
2191 Female, age 85, both hemispheres 203.6
2307 Male, age 80, both hemispheres 203.0
Paramedian reticular nucleus
nTPM: 261.3
2050 Female, age 85, both hemispheres 297.2
2057 Male, age 80, both hemispheres 250.9
2313 Male, age 61, both hemispheres 250.0
2052 Male, age 76, both hemispheres 247.0
Parvicellular reticular nuclei
nTPM: 242.3
2095 Male, age 76, both hemispheres 249.2
2119 Male, age 80, both hemispheres 243.8
2558 Male, age 74, both hemispheres 233.9
Parvicellular reticular nuclei, medullary
nTPM: 254.0
2189 Female, age 91, both hemispheres 273.2
2181 Male, age 80, left hemisphere 245.1
2091 Female, age 85, both hemispheres 243.8
Peritrigeminal nucleus
nTPM: 249.3
2136 Male, age 76, both hemispheres 256.1
2179 Male, age 61, both hemispheres 248.9
2067 Female, age 85, both hemispheres 243.0
Pontine nuclei
nTPM: 290.2
2787 Female, age 85, both hemispheres 368.1
2727 Male, age 61, right hemisphere 334.1
1863 Male, age 55, unknown 324.6
1968 Male, age 76, left hemisphere 289.6
2109 Female, age 72, unknown 280.4
2454 Male, age 74, left hemisphere 259.8
2319 Female, age 91, both hemispheres 247.3
2115 Male, age 80, left hemisphere 217.8
Pontine raphe nucleus
nTPM: 276.9
2122 Female, age 85, midline 312.9
2853 Male, age 76, midline 240.8
Posteroventral cochlear nucleus
nTPM: 241.8
2752 Female, age 85, both hemispheres 264.4
2070 Male, age 76, both hemispheres 242.6
2135 Female, age 91, both hemispheres 236.9
2341 Male, age 80, both hemispheres 235.3
2371 Male, age 61, both hemispheres 230.0
Prepositus hypoglossal nucleus
nTPM: 239.9
2855 Female, age 85, right hemisphere 248.8
2086 Male, age 80, both hemispheres 231.0
Principal sensory trigeminal nucleus
nTPM: 252.5
2158 Male, age 61, both hemispheres 280.3
2008 Male, age 80, left hemisphere 265.2
2367 Female, age 91, left hemisphere 234.7
2324 Male, age 76, both hemispheres 229.7
Reticular pontine nucleus, caudal
nTPM: 246.1
2092 Male, age 76, both hemispheres 292.1
2559 Male, age 74, both hemispheres 241.3
2457 Female, age 91, both hemispheres 227.3
2332 Male, age 80, right hemisphere 223.8
Reticular pontine nucleus, oral
nTPM: 263.9
2012 Female, age 85, both hemispheres 294.0
2361 Male, age 74, both hemispheres 293.0
1939 Male, age 80, both hemispheres 257.7
2167 Male, age 76, both hemispheres 242.5
2366 Female, age 91, both hemispheres 232.1
Reticulotegmental nucleus
nTPM: 242.5
2325 Male, age 76, both hemispheres 264.2
2452 Male, age 74, both hemispheres 245.2
2322 Female, age 91, both hemispheres 232.9
2333 Male, age 80, both hemispheres 227.6
Spinal trigeminal nucleus, caudal
nTPM: 235.9
2390 Female, age 91, both hemispheres 269.6
2312 Male, age 61, both hemispheres 237.8
2642 Male, age 74, both hemispheres 226.5
2308 Male, age 80, both hemispheres 223.1
2447 Male, age 76, both hemispheres 222.5
Spinal trigeminal nucleus, interpolar
nTPM: 260.7
2066 Male, age 76, right hemisphere 297.9
2625 Male, age 61, both hemispheres 253.6
2386 Female, age 85, both hemispheres 252.7
2389 Female, age 91, both hemispheres 251.5
2033 Male, age 80, both hemispheres 247.8
Spinal trigeminal nucleus, oral
nTPM: 243.7
2737 Female, age 85, both hemispheres 258.8
1978 Male, age 76, both hemispheres 236.2
2164 Male, age 80, both hemispheres 236.1
Spinal vestibular nucleus
nTPM: 253.0
2186 Female, age 91, both hemispheres 268.6
2806 Female, age 85, both hemispheres 262.6
2780 Male, age 80, both hemispheres 258.3
2748 Male, age 76, both hemispheres 247.5
2384 Male, age 74, both hemispheres 242.9
2796 Male, age 61, both hemispheres 237.9
Subcoeruleus area
nTPM: 252.5
1958 Male, age 80, both hemispheres 272.0
2323 Female, age 91, left hemisphere 262.1
2089 Male, age 76, left hemisphere 250.4
2369 Female, age 85, left hemisphere 242.6
2451 Male, age 74, both hemispheres 235.3
Superior olive
nTPM: 269.2
1875 Female, age 85, both hemispheres 338.4
2020 Male, age 76, both hemispheres 284.3
2364 Male, age 74, right hemisphere 278.9
2329 Male, age 80, right hemisphere 224.5
2561 Female, age 91, both hemispheres 220.1
Superior vestibular nucleus
nTPM: 250.5
2383 Male, age 74, both hemispheres 278.4
2015 Male, age 80, both hemispheres 252.6
2061 Male, age 76, both hemispheres 220.6
Ventral medullary reticular nucleus
nTPM: 235.6
2372 Male, age 61, both hemispheres 236.4
2060 Male, age 76, both hemispheres 234.9
Ventral periolivary nuclei
nTPM: 270.0
2130 Female, age 85, both hemispheres 297.6
2023 Male, age 76, both hemispheres 289.0
2165 Male, age 80, both hemispheres 264.8
2794 Female, age 91, left hemisphere 228.4
Ventrolateral medulla, A1-C1 cell groups
nTPM: 243.7
1986 Male, age 76, both hemispheres 260.4
2741 Female, age 85, both hemispheres 256.4
2180 Male, age 61, both hemispheres 249.3
2302 Female, age 91, both hemispheres 230.1
2118 Male, age 80, both hemispheres 222.1
Ventrolateral tegmental area, A5 NE cell group
nTPM: 252.1
1959 Male, age 76, both hemispheres 280.0
2840 Female, age 85, both hemispheres 269.3
2449 Male, age 74, both hemispheres 260.7
2359 Male, age 61, both hemispheres 242.9
2161 Male, age 80, both hemispheres 239.3
2456 Female, age 91, both hemispheres 220.5

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 830.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 531.3
FF:10182-103D2 60 years, female 572.3
FF:10165-103B3 76 years, female 490.4
Medulla oblongata
Scaled Tags Per Million: 475.8
FF:10174-103C3 60 years, female 554.1
FF:10155-103A2 76 years, female 447.1
FF:10038-101F2 18-64 years, mixed 426.1
Pons
Scaled Tags Per Million: 830.5
FF:10033-101E6 18-54 years, mixed 830.5

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 557.5
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 411.6
Samples: 4

Max nTPM: 459.9
Min nTPM: 391.4
Sample A Female 459.9
Sample B Female 400.1
Sample C Male 391.4
Sample D Male 394.9
Pons
nTPM: 557.5
Samples: 4

Max nTPM: 646.4
Min nTPM: 431.6
Sample A Female 646.4
Sample B Female 431.6
Sample C Male 579.9
Sample D Male 571.9

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 877.7
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 877.8
Samples: 4

Max nTPM: 905.5
Min nTPM: 852.7
Sample A Male 852.7
Sample B Male 897.4
Sample C Female 855.4
Sample D Female 905.5

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.6
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 15.6
71381013 Antisense, RP_050428_02_F12, Mouse strain C57BL/6J (56 days, male) 15.6
Pons
Expression energy: 15.4
71381013 Antisense, RP_050428_02_F12, Mouse strain C57BL/6J (56 days, male) 15.4

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