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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:127.8 nTPM
HPA:127.8 nTPM
GTEx:195.0 nTPM
FANTOM5:95.0 Scaled Tags Per Million
Pig:112.4 nTPM
Mouse:287.8 nTPM
Allen mouse:12.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 127.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 103.1
2586 Male, age 75, left hemisphere 145.8
2666 Male, age 74, left hemisphere 129.5
2828 Female, age 72, unknown 114.1
1827 Male, age 72, unknown 106.1
2019 Male, age 18, unknown 96.8
2219 Male, age 76, both hemispheres 96.8
2411 Female, age 72, unknown 96.7
1870 Female, age 42, unknown 86.7
1833 Male, age 53, unknown 80.3
1830 Male, age 51, unknown 77.6
Dorsal raphe nucleus
nTPM: 104.4
2047 Male, age 72, unknown 117.3
1828 Male, age 53, unknown 113.8
2298 Female, age 72, unknown 108.2
2750 Male, age 76, both hemispheres 93.5
2016 Female, age 72, unknown 89.3
Inferior colliculus
nTPM: 89.3
2097 Female, age 72, unknown 102.2
1890 Male, age 53, unknown 93.2
1848 Female, age 42, unknown 84.2
2849 Male, age 72, unknown 77.6
Median raphe nucleus
nTPM: 94.8
2220 Male, age 76, midline 94.8
Pedunculopontine tegmental nucleus
nTPM: 83.0
2334 Male, age 80, both hemispheres 94.5
1921 Female, age 85, both hemispheres 92.1
2338 Male, age 61, both hemispheres 62.5
Periaquaductal grey, anterior
nTPM: 127.3
1947 Male, age 18, unknown 141.1
1795 Male, age 51, unknown 130.6
2502 Female, age 75, unknown 110.1
Periaquaductal grey, dorsal
nTPM: 78.0
1840 Male, age 53, unknown 84.9
2464 Female, age 72, unknown 82.6
1831 Male, age 72, unknown 76.5
2850 Male, age 76, both hemispheres 68.0
Periaquaductal grey, lateral
nTPM: 77.3
2053 Male, age 18, unknown 82.5
2272 Male, age 74, both hemispheres 80.8
2140 Male, age 76, both hemispheres 68.7
Pretectal area
nTPM: 99.7
2007 Male, age 72, unknown 128.0
1816 Male, age 51, unknown 127.0
1817 Female, age 42, unknown 113.7
1944 Female, age 72, unknown 107.9
2667 Female, age 75, unknown 103.4
1815 Male, age 53, unknown 99.3
2825 Male, age 18, unknown 89.1
2224 Female, age 72, unknown 87.7
2407 Male, age 75, both hemispheres 85.3
2273 Male, age 74, both hemispheres 83.9
2316 Male, age 76, right hemisphere 71.6
Red nucleus
nTPM: 98.8
2588 Male, age 74, left hemisphere 120.7
2503 Female, age 72, unknown 117.7
1821 Female, age 72, unknown 110.4
2769 Male, age 72, unknown 100.5
2725 Female, age 75, unknown 99.6
2227 Male, age 72, unknown 99.5
2785 Male, age 18, unknown 95.5
1954 Female, age 42, unknown 93.4
2584 Male, age 75, left hemisphere 92.3
1904 Male, age 53, unknown 90.1
1865 Male, age 51, unknown 85.8
2823 Male, age 76, right hemisphere 80.4
Substantia nigra
nTPM: 127.8
1916 Female, age 42, unknown 181.2
1851 Male, age 51, unknown 154.0
2665 Male, age 74, both hemispheres 144.7
1941 Male, age 53, unknown 142.7
2241 Male, age 72, unknown 118.5
1889 Female, age 72, unknown 114.9
2590 Female, age 75, unknown 110.1
2583 Male, age 75, right hemisphere 108.2
2699 Male, age 18, unknown 105.1
2409 Female, age 72, unknown 98.5
Superior colliculus
nTPM: 95.0
2668 Female, age 75, unknown 114.1
2261 Male, age 18, unknown 110.5
1796 Male, age 53, unknown 110.1
2664 Male, age 75, both hemispheres 107.9
2087 Female, age 72, unknown 103.8
2587 Male, age 74, left hemisphere 97.5
1839 Male, age 51, unknown 84.8
1913 Female, age 42, unknown 75.3
1895 Male, age 76, right hemisphere 73.6
1995 Male, age 72, unknown 72.0
Ventral tegmental area
nTPM: 111.2
1915 Female, age 42, unknown 134.1
2410 Female, age 72, unknown 126.5
2218 Male, age 76, both hemispheres 115.7
1942 Male, age 51, unknown 110.8
2223 Female, age 72, unknown 91.6
2021 Male, age 53, unknown 88.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 195.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 195.0
Samples: 139

Max nTPM: 333.6
Min nTPM: 102.8
Std nTPM: 48.3
Median nTPM: 186.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 333.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 324.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 316.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 311.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 298.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 298.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 296.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 289.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 289.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 279.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 271.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 265.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 265.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 262.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 259.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 258.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 254.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 250.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 250.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 250.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 249.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 248.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 245.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 245.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 245.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 231.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 230.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 229.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 227.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 227.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 226.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 226.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 226.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 225.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 224.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 218.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 218.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 217.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 216.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 215.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 215.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 214.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 214.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 213.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 213.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 208.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 207.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 206.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 206.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 205.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 205.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 204.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 204.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 204.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 204.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 203.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 203.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 203.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 199.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 197.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 196.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 194.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 193.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 193.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 193.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 193.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 190.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 190.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 188.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 186.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 185.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 185.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 185.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 184.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 184.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 183.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 183.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 181.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 180.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 178.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 178.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 177.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 176.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 176.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 176.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 175.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 174.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 174.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 173.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 173.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 171.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 169.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 169.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 168.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 168.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 167.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 165.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 165.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 164.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 163.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 163.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 162.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 162.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 162.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 162.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 162.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 161.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 161.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 160.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 158.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 157.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 157.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 155.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 152.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 152.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 150.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 149.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 148.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 147.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 147.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 146.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 143.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 143.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 142.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 140.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 137.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 133.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 133.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 131.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 131.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 131.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 128.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 127.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 116.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 110.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 109.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 107.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 106.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 102.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 95.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 95.0
FF:10158-103A5 76 years, female 95.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 112.4
Pig sample Sample description nTPM
Midbrain
nTPM: 112.5
Samples: 4

Max nTPM: 147.3
Min nTPM: 91.0
Sample A Female 147.3
Sample B Female 109.9
Sample C Male 101.6
Sample D Male 91.0
Periaqueductal gray
nTPM: 89.3
Samples: 3

Max nTPM: 96.5
Min nTPM: 82.4
Sample B Female 96.5
Sample C Male 89.0
Sample D Male 82.4
Substantia nigra
nTPM: 112.3
Samples: 4

Max nTPM: 136.7
Min nTPM: 94.1
Sample A Female 136.7
Sample B Female 94.1
Sample C Male 117.4
Sample D Male 100.8
Superior colliculi
nTPM: 100.1
Samples: 4

Max nTPM: 119.1
Min nTPM: 75.6
Sample A Female 119.1
Sample B Female 75.6
Sample C Male 102.0
Sample D Male 103.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 287.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 287.8
Samples: 4

Max nTPM: 321.6
Min nTPM: 273.7
Sample A Male 321.6
Sample B Male 276.2
Sample C Female 279.6
Sample D Female 273.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.1
69783208 Antisense, RP_050505_04_E11, Mouse strain C57BL/6J (56 days, male) 12.1

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