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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:763.2 nTPM
HPA:763.2 nTPM
GTEx:347.7 nTPM
FANTOM5:1760.9 Scaled Tags Per Million
Pig:394.8 nTPM
Mouse:267.6 nTPM
Allen mouse:0.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 763.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 652.0
1870 Female, age 42, unknown 709.6
2019 Male, age 18, unknown 687.8
1833 Male, age 53, unknown 669.9
1830 Male, age 51, unknown 669.8
2828 Female, age 72, unknown 659.4
2411 Female, age 72, unknown 655.9
2666 Male, age 74, left hemisphere 655.7
1827 Male, age 72, unknown 627.2
2219 Male, age 76, both hemispheres 603.4
2586 Male, age 75, left hemisphere 581.6
Dorsal raphe nucleus
nTPM: 688.6
1828 Male, age 53, unknown 724.6
2298 Female, age 72, unknown 705.1
2016 Female, age 72, unknown 692.9
2750 Male, age 76, both hemispheres 679.6
2047 Male, age 72, unknown 640.6
Inferior colliculus
nTPM: 650.9
2097 Female, age 72, unknown 689.6
1848 Female, age 42, unknown 653.3
1890 Male, age 53, unknown 637.6
2849 Male, age 72, unknown 623.2
Median raphe nucleus
nTPM: 653.8
2220 Male, age 76, midline 653.8
Pedunculopontine tegmental nucleus
nTPM: 763.2
2338 Male, age 61, both hemispheres 939.3
2334 Male, age 80, both hemispheres 709.3
1921 Female, age 85, both hemispheres 641.0
Periaquaductal grey, anterior
nTPM: 670.3
2502 Female, age 75, unknown 717.2
1947 Male, age 18, unknown 652.6
1795 Male, age 51, unknown 641.0
Periaquaductal grey, dorsal
nTPM: 656.7
2850 Male, age 76, both hemispheres 677.9
1831 Male, age 72, unknown 674.8
2464 Female, age 72, unknown 656.3
1840 Male, age 53, unknown 617.7
Periaquaductal grey, lateral
nTPM: 669.7
2272 Male, age 74, both hemispheres 682.1
2053 Male, age 18, unknown 666.1
2140 Male, age 76, both hemispheres 661.1
Pretectal area
nTPM: 650.0
1817 Female, age 42, unknown 678.8
2316 Male, age 76, right hemisphere 670.2
2224 Female, age 72, unknown 666.7
2667 Female, age 75, unknown 664.2
2273 Male, age 74, both hemispheres 661.8
2007 Male, age 72, unknown 656.6
1815 Male, age 53, unknown 649.0
1944 Female, age 72, unknown 647.0
2825 Male, age 18, unknown 640.3
1816 Male, age 51, unknown 624.0
2407 Male, age 75, both hemispheres 591.1
Red nucleus
nTPM: 696.5
1954 Female, age 42, unknown 754.5
1821 Female, age 72, unknown 748.9
1865 Male, age 51, unknown 726.5
2503 Female, age 72, unknown 717.2
2823 Male, age 76, right hemisphere 714.9
2769 Male, age 72, unknown 712.7
2227 Male, age 72, unknown 702.3
1904 Male, age 53, unknown 694.7
2785 Male, age 18, unknown 691.1
2725 Female, age 75, unknown 663.7
2584 Male, age 75, left hemisphere 615.8
2588 Male, age 74, left hemisphere 615.3
Substantia nigra
nTPM: 687.4
2409 Female, age 72, unknown 756.6
2699 Male, age 18, unknown 712.6
1851 Male, age 51, unknown 708.6
2665 Male, age 74, both hemispheres 704.8
2241 Male, age 72, unknown 688.2
1889 Female, age 72, unknown 672.5
2590 Female, age 75, unknown 669.0
1941 Male, age 53, unknown 664.1
1916 Female, age 42, unknown 661.3
2583 Male, age 75, right hemisphere 636.8
Superior colliculus
nTPM: 656.8
1913 Female, age 42, unknown 718.9
1995 Male, age 72, unknown 692.1
2587 Male, age 74, left hemisphere 685.0
1895 Male, age 76, right hemisphere 669.0
1796 Male, age 53, unknown 658.4
2087 Female, age 72, unknown 653.9
1839 Male, age 51, unknown 648.9
2668 Female, age 75, unknown 632.5
2261 Male, age 18, unknown 620.2
2664 Male, age 75, both hemispheres 589.0
Ventral tegmental area
nTPM: 689.0
2410 Female, age 72, unknown 714.6
2021 Male, age 53, unknown 699.3
1915 Female, age 42, unknown 697.8
2218 Male, age 76, both hemispheres 674.7
2223 Female, age 72, unknown 673.9
1942 Male, age 51, unknown 673.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 347.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 347.7
Samples: 139

Max nTPM: 1281.6
Min nTPM: 50.4
Std nTPM: 182.4
Median nTPM: 309.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1281.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 801.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 715.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 711.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 694.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 676.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 671.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 668.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 660.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 645.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 639.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 628.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 599.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 594.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 576.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 571.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 570.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 565.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 553.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 551.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 546.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 533.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 533.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 529.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 524.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 523.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 520.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 504.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 485.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 479.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 478.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 474.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 471.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 464.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 462.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 461.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 458.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 448.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 440.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 438.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 436.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 428.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 424.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 423.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 413.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 393.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 388.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 388.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 370.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 368.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 356.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 355.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 355.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 351.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 350.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 350.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 348.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 347.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 342.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 338.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 338.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 333.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 326.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 325.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 325.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 322.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 316.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 315.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 315.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 309.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 307.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 306.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 305.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 301.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 297.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 292.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 291.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 290.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 289.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 282.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 274.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 274.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 273.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 270.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 268.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 267.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 264.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 264.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 259.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 257.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 253.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 247.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 239.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 238.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 238.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 236.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 229.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 229.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 228.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 227.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 227.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 224.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 223.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 223.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 218.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 218.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 215.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 213.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 212.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 206.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 195.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 194.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 193.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 189.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 189.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 182.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 181.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 181.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 180.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 178.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 171.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 167.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 166.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 163.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 156.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 145.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 141.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 140.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 136.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 130.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 128.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 124.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 116.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 100.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 95.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 82.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 68.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 60.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 50.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1760.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1760.9
FF:10158-103A5 76 years, female 1760.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 394.8
Pig sample Sample description nTPM
Midbrain
nTPM: 269.2
Samples: 4

Max nTPM: 353.8
Min nTPM: 189.7
Sample A Female 353.8
Sample B Female 299.7
Sample C Male 233.5
Sample D Male 189.7
Periaqueductal gray
nTPM: 232.3
Samples: 3

Max nTPM: 285.0
Min nTPM: 185.9
Sample B Female 285.0
Sample C Male 226.1
Sample D Male 185.9
Substantia nigra
nTPM: 394.8
Samples: 4

Max nTPM: 567.6
Min nTPM: 285.9
Sample A Female 419.3
Sample B Female 567.6
Sample C Male 285.9
Sample D Male 306.3
Superior colliculi
nTPM: 382.7
Samples: 4

Max nTPM: 603.0
Min nTPM: 278.7
Sample A Female 357.5
Sample B Female 603.0
Sample C Male 278.7
Sample D Male 291.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 267.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 267.6
Samples: 4

Max nTPM: 274.7
Min nTPM: 256.4
Sample A Male 269.4
Sample B Male 269.9
Sample C Female 256.4
Sample D Female 274.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.8
70305443 Antisense, RP_050609_04_B12, Mouse strain C57BL/6J (56 days, male) 0.8
71924291 Antisense, RP_050609_04_B12, Mouse strain C57BL/6J (56 days, male) 0.6

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