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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:61.8 nTPM
HPA:61.8 nTPM
GTEx:87.0 nTPM
FANTOM5:57.0 Scaled Tags Per Million
Pig:71.7 nTPM
Mouse:29.6 nTPM
Allen mouse:7.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 61.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 58.6
2586 Male, age 75, left hemisphere 71.3
2666 Male, age 74, left hemisphere 65.1
1827 Male, age 72, unknown 63.4
2219 Male, age 76, both hemispheres 59.5
2828 Female, age 72, unknown 57.1
2411 Female, age 72, unknown 56.3
2019 Male, age 18, unknown 54.7
1833 Male, age 53, unknown 53.3
1830 Male, age 51, unknown 53.1
1870 Female, age 42, unknown 52.6
Dorsal raphe nucleus
nTPM: 56.3
2047 Male, age 72, unknown 61.5
2298 Female, age 72, unknown 58.0
1828 Male, age 53, unknown 57.8
2750 Male, age 76, both hemispheres 55.2
2016 Female, age 72, unknown 48.9
Inferior colliculus
nTPM: 53.9
2097 Female, age 72, unknown 57.3
2849 Male, age 72, unknown 53.9
1890 Male, age 53, unknown 53.0
1848 Female, age 42, unknown 51.6
Median raphe nucleus
nTPM: 58.5
2220 Male, age 76, midline 58.5
Pedunculopontine tegmental nucleus
nTPM: 55.4
1921 Female, age 85, both hemispheres 58.7
2334 Male, age 80, both hemispheres 57.6
2338 Male, age 61, both hemispheres 49.9
Periaquaductal grey, anterior
nTPM: 61.8
1795 Male, age 51, unknown 64.6
1947 Male, age 18, unknown 63.7
2502 Female, age 75, unknown 57.2
Periaquaductal grey, dorsal
nTPM: 52.5
1840 Male, age 53, unknown 54.1
2464 Female, age 72, unknown 53.8
2850 Male, age 76, both hemispheres 51.0
1831 Male, age 72, unknown 50.9
Periaquaductal grey, lateral
nTPM: 49.3
2140 Male, age 76, both hemispheres 50.5
2272 Male, age 74, both hemispheres 48.8
2053 Male, age 18, unknown 48.6
Pretectal area
nTPM: 56.9
1816 Male, age 51, unknown 67.0
2007 Male, age 72, unknown 66.5
1817 Female, age 42, unknown 64.3
1944 Female, age 72, unknown 60.4
1815 Male, age 53, unknown 59.7
2667 Female, age 75, unknown 56.6
2825 Male, age 18, unknown 53.1
2224 Female, age 72, unknown 52.6
2407 Male, age 75, both hemispheres 51.9
2273 Male, age 74, both hemispheres 47.3
2316 Male, age 76, right hemisphere 46.3
Red nucleus
nTPM: 54.6
2588 Male, age 74, left hemisphere 61.3
2584 Male, age 75, left hemisphere 60.4
2785 Male, age 18, unknown 58.5
2769 Male, age 72, unknown 55.4
1821 Female, age 72, unknown 55.1
2227 Male, age 72, unknown 54.9
2503 Female, age 72, unknown 54.9
1954 Female, age 42, unknown 52.9
2725 Female, age 75, unknown 52.5
1865 Male, age 51, unknown 50.3
1904 Male, age 53, unknown 49.4
2823 Male, age 76, right hemisphere 49.3
Substantia nigra
nTPM: 58.5
1916 Female, age 42, unknown 68.6
2665 Male, age 74, both hemispheres 67.9
1941 Male, age 53, unknown 64.4
1889 Female, age 72, unknown 61.0
1851 Male, age 51, unknown 60.1
2699 Male, age 18, unknown 59.3
2583 Male, age 75, right hemisphere 53.8
2590 Female, age 75, unknown 51.6
2409 Female, age 72, unknown 49.8
2241 Male, age 72, unknown 48.1
Superior colliculus
nTPM: 56.4
2668 Female, age 75, unknown 70.5
1796 Male, age 53, unknown 60.7
2664 Male, age 75, both hemispheres 59.8
2087 Female, age 72, unknown 58.7
2261 Male, age 18, unknown 56.5
1839 Male, age 51, unknown 53.4
2587 Male, age 74, left hemisphere 52.8
1895 Male, age 76, right hemisphere 52.6
1913 Female, age 42, unknown 50.4
1995 Male, age 72, unknown 48.9
Ventral tegmental area
nTPM: 55.9
1915 Female, age 42, unknown 62.7
2218 Male, age 76, both hemispheres 57.7
2410 Female, age 72, unknown 57.3
1942 Male, age 51, unknown 54.2
2223 Female, age 72, unknown 53.1
2021 Male, age 53, unknown 50.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 87.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 87.0
Samples: 139

Max nTPM: 213.3
Min nTPM: 37.4
Std nTPM: 25.6
Median nTPM: 84.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 213.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 142.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 141.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 139.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 137.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 136.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 135.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 135.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 132.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 129.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 128.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 128.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 125.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 123.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 122.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 119.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 118.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 117.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 115.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 114.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 112.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 111.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 110.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 110.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 109.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 109.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 109.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 108.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 107.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 103.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 102.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 100.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 99.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 99.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 99.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 98.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 98.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 98.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 95.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 95.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 95.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 94.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 93.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 92.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 92.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 92.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 92.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 91.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 91.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 90.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 90.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 90.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 89.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 89.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 89.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 88.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 88.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 88.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 88.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 88.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 87.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 86.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 86.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 86.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 86.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 86.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 86.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 85.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 85.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 84.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 84.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 84.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 84.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 84.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 83.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 81.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 81.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 81.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 80.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 80.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 78.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 78.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 77.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 77.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 76.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 75.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 75.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 75.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 75.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 75.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 75.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 73.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 73.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 73.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 72.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 71.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 71.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 71.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 70.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 70.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 70.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 69.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 69.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 68.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 68.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 68.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 68.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 67.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 66.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 66.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 66.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 65.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 64.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 64.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 64.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 63.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 63.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 63.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 63.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 63.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 63.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 60.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 60.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 59.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 57.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 57.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 56.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 55.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 53.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 53.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 53.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 52.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 50.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 47.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 45.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 44.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 37.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 37.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 57.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 57.0
FF:10158-103A5 76 years, female 57.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 71.7
Pig sample Sample description nTPM
Midbrain
nTPM: 69.8
Samples: 4

Max nTPM: 81.0
Min nTPM: 49.9
Sample A Female 49.9
Sample B Female 70.3
Sample C Male 77.9
Sample D Male 81.0
Periaqueductal gray
nTPM: 58.9
Samples: 3

Max nTPM: 70.4
Min nTPM: 52.7
Sample B Female 53.6
Sample C Male 70.4
Sample D Male 52.7
Substantia nigra
nTPM: 65.3
Samples: 4

Max nTPM: 90.0
Min nTPM: 39.1
Sample A Female 90.0
Sample B Female 54.7
Sample C Male 77.5
Sample D Male 39.1
Superior colliculi
nTPM: 71.7
Samples: 4

Max nTPM: 92.6
Min nTPM: 47.9
Sample A Female 92.6
Sample B Female 47.9
Sample C Male 73.0
Sample D Male 73.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 29.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 29.6
Samples: 4

Max nTPM: 32.2
Min nTPM: 25.6
Sample A Male 32.2
Sample B Male 30.0
Sample C Female 25.6
Sample D Female 30.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.0
70598359 Antisense, RP_050407_04_D04, Mouse strain C57BL/6J (56 days, male) 7.3
74988737 Antisense, RP_060315_04_B05, Mouse strain C57BL/6J (56 days, male) 6.7

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