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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:64.8 nTPM
HPA:64.8 nTPM
GTEx:60.2 nTPM
FANTOM5:134.7 Scaled Tags Per Million
Pig:56.5 nTPM
Mouse:99.6 nTPM
Allen mouse:2.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 64.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.0
2586 Male, age 75, left hemisphere 77.8
2666 Male, age 74, left hemisphere 64.1
1870 Female, age 42, unknown 62.5
2019 Male, age 18, unknown 60.9
1827 Male, age 72, unknown 60.2
1833 Male, age 53, unknown 60.2
1830 Male, age 51, unknown 60.1
2411 Female, age 72, unknown 60.1
2828 Female, age 72, unknown 59.3
2219 Male, age 76, both hemispheres 54.6
Dorsal raphe nucleus
nTPM: 59.9
2047 Male, age 72, unknown 61.9
1828 Male, age 53, unknown 60.9
2750 Male, age 76, both hemispheres 60.4
2298 Female, age 72, unknown 59.5
2016 Female, age 72, unknown 56.9
Inferior colliculus
nTPM: 57.5
1848 Female, age 42, unknown 58.2
2849 Male, age 72, unknown 57.9
2097 Female, age 72, unknown 57.1
1890 Male, age 53, unknown 56.7
Median raphe nucleus
nTPM: 58.2
2220 Male, age 76, midline 58.2
Pedunculopontine tegmental nucleus
nTPM: 59.1
2338 Male, age 61, both hemispheres 63.7
2334 Male, age 80, both hemispheres 59.3
1921 Female, age 85, both hemispheres 54.3
Periaquaductal grey, anterior
nTPM: 58.5
2502 Female, age 75, unknown 59.7
1947 Male, age 18, unknown 59.2
1795 Male, age 51, unknown 56.6
Periaquaductal grey, dorsal
nTPM: 55.6
1840 Male, age 53, unknown 58.7
2464 Female, age 72, unknown 56.9
1831 Male, age 72, unknown 55.2
2850 Male, age 76, both hemispheres 51.8
Periaquaductal grey, lateral
nTPM: 53.8
2053 Male, age 18, unknown 57.1
2140 Male, age 76, both hemispheres 52.4
2272 Male, age 74, both hemispheres 52.1
Pretectal area
nTPM: 59.2
2407 Male, age 75, both hemispheres 68.4
1816 Male, age 51, unknown 61.8
1817 Female, age 42, unknown 60.9
1944 Female, age 72, unknown 60.9
2007 Male, age 72, unknown 60.6
2825 Male, age 18, unknown 58.7
1815 Male, age 53, unknown 58.2
2667 Female, age 75, unknown 57.8
2224 Female, age 72, unknown 57.3
2316 Male, age 76, right hemisphere 55.0
2273 Male, age 74, both hemispheres 52.1
Red nucleus
nTPM: 60.2
2584 Male, age 75, left hemisphere 76.4
2769 Male, age 72, unknown 60.2
2227 Male, age 72, unknown 60.0
1821 Female, age 72, unknown 59.9
2785 Male, age 18, unknown 59.8
1954 Female, age 42, unknown 59.7
1865 Male, age 51, unknown 58.9
1904 Male, age 53, unknown 58.9
2588 Male, age 74, left hemisphere 58.8
2725 Female, age 75, unknown 58.2
2503 Female, age 72, unknown 57.2
2823 Male, age 76, right hemisphere 54.7
Substantia nigra
nTPM: 64.8
2583 Male, age 75, right hemisphere 75.5
1916 Female, age 42, unknown 67.8
2590 Female, age 75, unknown 66.0
1851 Male, age 51, unknown 65.8
2665 Male, age 74, both hemispheres 65.8
2241 Male, age 72, unknown 64.4
1941 Male, age 53, unknown 64.1
2699 Male, age 18, unknown 59.9
1889 Female, age 72, unknown 59.4
2409 Female, age 72, unknown 59.0
Superior colliculus
nTPM: 59.9
2664 Male, age 75, both hemispheres 71.5
2087 Female, age 72, unknown 60.6
2261 Male, age 18, unknown 60.6
1839 Male, age 51, unknown 60.3
2668 Female, age 75, unknown 60.2
1796 Male, age 53, unknown 59.7
2587 Male, age 74, left hemisphere 57.8
1995 Male, age 72, unknown 57.2
1913 Female, age 42, unknown 56.6
1895 Male, age 76, right hemisphere 54.5
Ventral tegmental area
nTPM: 61.5
2223 Female, age 72, unknown 65.7
1915 Female, age 42, unknown 62.8
1942 Male, age 51, unknown 61.6
2021 Male, age 53, unknown 61.4
2218 Male, age 76, both hemispheres 58.9
2410 Female, age 72, unknown 58.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 60.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 60.2
Samples: 139

Max nTPM: 93.3
Min nTPM: 42.5
Std nTPM: 9.0
Median nTPM: 58.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 93.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 83.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 82.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 82.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 81.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 78.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 77.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 77.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 76.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 75.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 74.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 74.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 73.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 73.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 73.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 71.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 70.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 69.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 68.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 68.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 68.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 68.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 67.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 67.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 67.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 67.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 67.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 65.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 65.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 65.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 65.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 64.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 64.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 64.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 64.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 64.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 64.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 63.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 63.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 63.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 62.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 62.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 62.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 62.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 62.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 62.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 62.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 62.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 61.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 61.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 61.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 61.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 61.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 61.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 61.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 61.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 60.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 60.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 59.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 59.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 59.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 59.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 59.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 58.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 58.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 58.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 58.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 58.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 58.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 58.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 58.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 58.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 57.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 57.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 57.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 57.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 57.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 57.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 57.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 57.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 57.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 56.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 56.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 56.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 56.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 55.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 55.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 55.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 55.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 55.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 55.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 55.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 55.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 55.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 55.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 55.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 54.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 54.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 54.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 54.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 54.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 54.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 53.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 53.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 53.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 52.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 52.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 52.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 52.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 52.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 52.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 52.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 52.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 51.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 51.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 51.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 51.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 51.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 51.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 50.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 50.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 50.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 50.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 49.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 49.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 49.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 49.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 49.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 48.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 48.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 47.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 45.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 45.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 45.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 42.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 134.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 134.7
FF:10158-103A5 76 years, female 134.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 56.5
Pig sample Sample description nTPM
Midbrain
nTPM: 56.6
Samples: 4

Max nTPM: 66.2
Min nTPM: 49.1
Sample A Female 66.2
Sample B Female 49.1
Sample C Male 57.0
Sample D Male 53.9
Periaqueductal gray
nTPM: 49.3
Samples: 3

Max nTPM: 56.1
Min nTPM: 43.9
Sample B Female 47.8
Sample C Male 56.1
Sample D Male 43.9
Substantia nigra
nTPM: 51.4
Samples: 4

Max nTPM: 61.5
Min nTPM: 40.8
Sample A Female 61.5
Sample B Female 46.1
Sample C Male 57.2
Sample D Male 40.8
Superior colliculi
nTPM: 54.6
Samples: 4

Max nTPM: 62.7
Min nTPM: 42.6
Sample A Female 62.7
Sample B Female 42.6
Sample C Male 59.7
Sample D Male 53.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 99.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 99.6
Samples: 4

Max nTPM: 107.6
Min nTPM: 88.4
Sample A Male 105.2
Sample B Male 107.6
Sample C Female 88.4
Sample D Female 97.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.5
69734584 Antisense, RP_050503_01_C02, Mouse strain C57BL/6J (56 days, male) 2.5

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