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PTP4A2
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  • PTP4A2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:286.3 nTPM
HPA:286.3 nTPM
GTEx:316.3 nTPM
FANTOM5:367.9 Scaled Tags Per Million
Pig:200.6 nTPM
Mouse:94.6 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 286.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 252.8
1833 Male, age 53, unknown 289.8
1830 Male, age 51, unknown 286.1
2666 Male, age 74, left hemisphere 285.5
2411 Female, age 72, unknown 275.6
1870 Female, age 42, unknown 258.9
2019 Male, age 18, unknown 250.7
2586 Male, age 75, left hemisphere 234.5
2828 Female, age 72, unknown 220.7
2219 Male, age 76, both hemispheres 216.8
1827 Male, age 72, unknown 209.2
Dorsal raphe nucleus
nTPM: 206.3
2750 Male, age 76, both hemispheres 247.6
2016 Female, age 72, unknown 225.2
1828 Male, age 53, unknown 210.9
2298 Female, age 72, unknown 174.1
2047 Male, age 72, unknown 173.5
Inferior colliculus
nTPM: 212.4
2849 Male, age 72, unknown 223.8
1848 Female, age 42, unknown 212.1
1890 Male, age 53, unknown 208.1
2097 Female, age 72, unknown 205.8
Median raphe nucleus
nTPM: 192.4
2220 Male, age 76, midline 192.4
Pedunculopontine tegmental nucleus
nTPM: 240.0
2334 Male, age 80, both hemispheres 259.2
2338 Male, age 61, both hemispheres 251.6
1921 Female, age 85, both hemispheres 209.3
Periaquaductal grey, anterior
nTPM: 206.5
2502 Female, age 75, unknown 241.1
1947 Male, age 18, unknown 208.2
1795 Male, age 51, unknown 170.1
Periaquaductal grey, dorsal
nTPM: 199.1
2464 Female, age 72, unknown 237.6
1831 Male, age 72, unknown 198.1
1840 Male, age 53, unknown 182.4
2850 Male, age 76, both hemispheres 178.3
Periaquaductal grey, lateral
nTPM: 183.9
2053 Male, age 18, unknown 206.6
2272 Male, age 74, both hemispheres 176.3
2140 Male, age 76, both hemispheres 168.9
Pretectal area
nTPM: 199.3
1815 Male, age 53, unknown 242.6
2316 Male, age 76, right hemisphere 227.1
1817 Female, age 42, unknown 216.0
2007 Male, age 72, unknown 210.8
2825 Male, age 18, unknown 207.6
2407 Male, age 75, both hemispheres 197.9
2224 Female, age 72, unknown 194.8
1944 Female, age 72, unknown 182.8
1816 Male, age 51, unknown 179.5
2667 Female, age 75, unknown 171.0
2273 Male, age 74, both hemispheres 162.1
Red nucleus
nTPM: 286.3
2503 Female, age 72, unknown 332.9
1904 Male, age 53, unknown 305.8
1821 Female, age 72, unknown 301.0
2588 Male, age 74, left hemisphere 297.9
1865 Male, age 51, unknown 297.7
1954 Female, age 42, unknown 285.7
2227 Male, age 72, unknown 280.2
2769 Male, age 72, unknown 276.0
2823 Male, age 76, right hemisphere 271.1
2785 Male, age 18, unknown 266.0
2725 Female, age 75, unknown 263.7
2584 Male, age 75, left hemisphere 257.8
Substantia nigra
nTPM: 232.5
2409 Female, age 72, unknown 284.0
2241 Male, age 72, unknown 251.6
1851 Male, age 51, unknown 244.4
2699 Male, age 18, unknown 237.0
2665 Male, age 74, both hemispheres 236.1
2590 Female, age 75, unknown 233.3
2583 Male, age 75, right hemisphere 221.5
1889 Female, age 72, unknown 212.6
1916 Female, age 42, unknown 204.1
1941 Male, age 53, unknown 200.5
Superior colliculus
nTPM: 228.3
1995 Male, age 72, unknown 272.7
1913 Female, age 42, unknown 272.2
2587 Male, age 74, left hemisphere 260.3
1839 Male, age 51, unknown 248.8
2668 Female, age 75, unknown 236.2
1895 Male, age 76, right hemisphere 221.7
2664 Male, age 75, both hemispheres 196.8
1796 Male, age 53, unknown 195.2
2087 Female, age 72, unknown 189.6
2261 Male, age 18, unknown 189.3
Ventral tegmental area
nTPM: 228.3
2410 Female, age 72, unknown 254.7
2223 Female, age 72, unknown 246.8
1942 Male, age 51, unknown 224.5
1915 Female, age 42, unknown 223.0
2021 Male, age 53, unknown 216.0
2218 Male, age 76, both hemispheres 204.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 316.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 316.3
Samples: 139

Max nTPM: 895.5
Min nTPM: 114.4
Std nTPM: 150.5
Median nTPM: 283.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 895.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 814.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 813.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 730.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 639.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 633.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 626.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 614.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 589.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 581.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 572.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 556.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 555.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 526.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 503.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 500.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 496.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 494.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 482.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 469.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 464.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 462.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 460.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 455.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 445.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 437.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 432.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 422.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 416.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 408.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 399.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 388.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 387.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 386.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 386.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 384.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 375.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 372.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 363.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 363.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 354.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 352.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 352.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 347.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 347.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 344.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 340.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 339.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 338.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 335.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 331.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 330.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 330.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 326.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 323.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 322.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 320.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 318.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 314.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 312.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 305.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 304.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 304.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 303.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 302.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 297.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 294.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 291.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 288.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 283.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 277.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 274.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 268.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 265.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 265.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 263.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 263.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 263.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 262.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 255.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 252.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 251.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 250.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 243.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 242.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 236.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 234.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 230.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 225.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 222.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 221.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 220.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 220.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 220.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 216.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 209.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 208.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 204.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 203.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 201.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 199.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 198.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 196.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 194.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 194.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 193.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 192.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 192.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 191.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 190.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 190.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 188.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 188.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 186.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 186.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 184.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 184.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 183.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 182.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 182.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 180.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 178.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 175.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 174.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 174.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 173.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 171.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 171.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 163.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 161.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 161.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 155.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 151.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 150.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 148.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 142.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 140.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 132.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 114.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 367.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 367.9
FF:10158-103A5 76 years, female 367.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 200.6
Pig sample Sample description nTPM
Midbrain
nTPM: 200.6
Samples: 4

Max nTPM: 322.0
Min nTPM: 138.4
Sample A Female 322.0
Sample B Female 197.7
Sample C Male 144.2
Sample D Male 138.4
Periaqueductal gray
nTPM: 155.3
Samples: 3

Max nTPM: 160.8
Min nTPM: 152.0
Sample B Female 160.8
Sample C Male 152.0
Sample D Male 153.1
Substantia nigra
nTPM: 190.8
Samples: 4

Max nTPM: 265.6
Min nTPM: 161.5
Sample A Female 265.6
Sample B Female 166.0
Sample C Male 170.0
Sample D Male 161.5
Superior colliculi
nTPM: 181.5
Samples: 4

Max nTPM: 273.4
Min nTPM: 122.1
Sample A Female 273.4
Sample B Female 122.1
Sample C Male 159.0
Sample D Male 171.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 94.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 94.6
Samples: 4

Max nTPM: 98.1
Min nTPM: 90.7
Sample A Male 92.2
Sample B Male 97.4
Sample C Female 98.1
Sample D Female 90.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
71280538 Antisense, RP_050818_01_A11, Mouse strain C57BL/6J (56 days, male) 0.8
77799059 Antisense, RP_070212_03_E04, Mouse strain C57BL/6J (56 days, male) 0.6
70813353 Antisense, RP_050712_03_G08, Mouse strain C57BL/6J (56 days, male) 0.1

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