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S100A6
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  • S100A6
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:488.9 nTPM
HPA:488.9 nTPM
GTEx:527.6 nTPM
FANTOM5:152.0 Scaled Tags Per Million
Pig:101.7 nTPM
Mouse:23.3 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 488.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 437.2
2828 Female, age 72, unknown 466.6
1870 Female, age 42, unknown 459.9
1830 Male, age 51, unknown 445.1
2666 Male, age 74, left hemisphere 444.3
2411 Female, age 72, unknown 439.1
2586 Male, age 75, left hemisphere 432.5
1833 Male, age 53, unknown 430.3
1827 Male, age 72, unknown 428.1
2019 Male, age 18, unknown 419.3
2219 Male, age 76, both hemispheres 406.8
Dorsal raphe nucleus
nTPM: 488.9
2047 Male, age 72, unknown 551.2
2298 Female, age 72, unknown 494.1
2016 Female, age 72, unknown 480.2
1828 Male, age 53, unknown 472.9
2750 Male, age 76, both hemispheres 445.9
Inferior colliculus
nTPM: 433.9
2097 Female, age 72, unknown 439.8
1848 Female, age 42, unknown 436.4
1890 Male, age 53, unknown 434.7
2849 Male, age 72, unknown 424.9
Median raphe nucleus
nTPM: 453.1
2220 Male, age 76, midline 453.1
Pedunculopontine tegmental nucleus
nTPM: 438.8
2338 Male, age 61, both hemispheres 450.3
2334 Male, age 80, both hemispheres 443.9
1921 Female, age 85, both hemispheres 422.3
Periaquaductal grey, anterior
nTPM: 462.9
1947 Male, age 18, unknown 475.6
2502 Female, age 75, unknown 457.4
1795 Male, age 51, unknown 455.7
Periaquaductal grey, dorsal
nTPM: 448.5
2850 Male, age 76, both hemispheres 475.3
1840 Male, age 53, unknown 451.2
2464 Female, age 72, unknown 437.1
1831 Male, age 72, unknown 430.2
Periaquaductal grey, lateral
nTPM: 479.9
2140 Male, age 76, both hemispheres 501.4
2053 Male, age 18, unknown 493.1
2272 Male, age 74, both hemispheres 445.2
Pretectal area
nTPM: 439.7
2825 Male, age 18, unknown 485.7
2316 Male, age 76, right hemisphere 467.0
2273 Male, age 74, both hemispheres 466.7
2224 Female, age 72, unknown 452.0
2407 Male, age 75, both hemispheres 447.9
2667 Female, age 75, unknown 442.8
1815 Male, age 53, unknown 422.1
1817 Female, age 42, unknown 421.7
1944 Female, age 72, unknown 413.5
2007 Male, age 72, unknown 410.4
1816 Male, age 51, unknown 406.6
Red nucleus
nTPM: 452.6
1954 Female, age 42, unknown 469.8
1865 Male, age 51, unknown 469.6
2725 Female, age 75, unknown 465.5
2769 Male, age 72, unknown 465.4
1904 Male, age 53, unknown 461.7
2227 Male, age 72, unknown 460.9
1821 Female, age 72, unknown 460.4
2503 Female, age 72, unknown 459.1
2823 Male, age 76, right hemisphere 447.7
2584 Male, age 75, left hemisphere 435.9
2588 Male, age 74, left hemisphere 424.2
2785 Male, age 18, unknown 410.8
Substantia nigra
nTPM: 461.8
1916 Female, age 42, unknown 486.2
2699 Male, age 18, unknown 482.7
1851 Male, age 51, unknown 481.0
2409 Female, age 72, unknown 478.5
2241 Male, age 72, unknown 476.1
1941 Male, age 53, unknown 470.5
2590 Female, age 75, unknown 446.7
2583 Male, age 75, right hemisphere 438.2
2665 Male, age 74, both hemispheres 430.4
1889 Female, age 72, unknown 427.4
Superior colliculus
nTPM: 432.2
2587 Male, age 74, left hemisphere 449.8
2664 Male, age 75, both hemispheres 449.0
1839 Male, age 51, unknown 440.5
1796 Male, age 53, unknown 435.7
1995 Male, age 72, unknown 432.7
1913 Female, age 42, unknown 426.9
2668 Female, age 75, unknown 426.5
2261 Male, age 18, unknown 422.7
1895 Male, age 76, right hemisphere 419.3
2087 Female, age 72, unknown 419.2
Ventral tegmental area
nTPM: 473.3
1915 Female, age 42, unknown 507.2
2223 Female, age 72, unknown 488.6
2021 Male, age 53, unknown 471.4
2410 Female, age 72, unknown 467.7
1942 Male, age 51, unknown 463.6
2218 Male, age 76, both hemispheres 441.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 527.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 527.6
Samples: 139

Max nTPM: 1848.7
Min nTPM: 170.8
Std nTPM: 255.2
Median nTPM: 447.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1848.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1789.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1132.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1125.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1092.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1021.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 987.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 958.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 920.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 907.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 888.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 867.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 862.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 826.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 815.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 813.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 808.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 779.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 774.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 763.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 761.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 755.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 754.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 732.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 725.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 714.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 697.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 693.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 689.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 684.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 670.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 666.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 643.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 625.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 625.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 612.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 609.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 599.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 597.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 587.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 583.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 583.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 578.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 565.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 562.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 553.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 551.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 551.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 542.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 539.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 537.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 529.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 525.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 520.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 509.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 497.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 497.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 495.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 492.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 490.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 488.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 481.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 475.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 474.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 469.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 469.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 468.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 459.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 450.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 447.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 447.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 445.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 441.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 440.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 440.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 432.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 427.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 425.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 425.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 424.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 423.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 423.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 423.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 422.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 417.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 415.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 414.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 410.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 403.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 402.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 398.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 394.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 389.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 387.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 386.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 386.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 383.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 383.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 373.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 371.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 369.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 366.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 361.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 359.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 358.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 357.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 355.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 354.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 354.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 350.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 350.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 349.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 344.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 343.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 341.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 340.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 339.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 335.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 332.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 324.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 321.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 317.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 315.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 311.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 310.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 302.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 290.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 286.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 284.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 275.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 275.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 267.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 265.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 265.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 237.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 224.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 222.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 212.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 170.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 152.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 152.0
FF:10158-103A5 76 years, female 152.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 101.7
Pig sample Sample description nTPM
Midbrain
nTPM: 70.4
Samples: 4

Max nTPM: 168.1
Min nTPM: 33.5
Sample A Female 168.1
Sample B Female 33.5
Sample C Male 41.0
Sample D Male 39.0
Periaqueductal gray
nTPM: 39.9
Samples: 3

Max nTPM: 49.6
Min nTPM: 30.4
Sample B Female 30.4
Sample C Male 49.6
Sample D Male 39.6
Substantia nigra
nTPM: 101.7
Samples: 4

Max nTPM: 135.2
Min nTPM: 79.8
Sample A Female 135.2
Sample B Female 86.9
Sample C Male 79.8
Sample D Male 104.8
Superior colliculi
nTPM: 56.0
Samples: 4

Max nTPM: 74.0
Min nTPM: 45.7
Sample A Female 74.0
Sample B Female 58.2
Sample C Male 45.7
Sample D Male 46.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 23.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 23.3
Samples: 4

Max nTPM: 25.3
Min nTPM: 21.5
Sample A Male 25.3
Sample B Male 24.7
Sample C Female 21.7
Sample D Female 21.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
75695667 Antisense, RP_060518_04_D06, Mouse strain C57BL/6J (56 days, male) 0.2
77278967 Antisense, RP_070116_01_A03, Mouse strain C57BL/6J (56 days, male) 0.1

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