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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 197.7
Min nTPM: 59.9
Std nTPM: 25.1
Median nTPM:
491_1
89 years, female
197.7
413_1
59 years, female
173.0
89_1
63 years, male
164.9
139_1
64 years, female
163.1
149_1
88 years, male
153.6
396_1
62 years, male
152.0
466_1
57 years, female
150.3
501_1
88 years, male
140.7
119_1
70 years, female
133.0
490_1
67 years, female
132.8
142_1
61 years, female
129.2
415_1
77 years, female
128.5
32_1
67 years, male
127.8
414_1
84 years, female
124.6
315_1
62 years, female
124.2
495_1
57 years, female
123.6
81_1
67 years, male
120.9
324_1
76 years, male
120.0
313_1
79 years, female
119.3
307_1
66 years, female
117.4
316_1
62 years, male
117.1
314_1
67 years, male
115.9
311_1
78 years, male
114.8
447_1
81 years, male
114.8
42_1
85 years, male
114.1
499_1
55 years, female
113.6
153_1
70 years, female
111.6
35_1
74 years, female
111.4
468_1
89 years, male
111.3
162_1
79 years, female
110.4
43_1
64 years, female
110.3
126_1
63 years, male
109.9
348_1
84 years, male
109.8
217_1
76 years, male
109.7
109_1
81 years, female
109.2
120_1
70 years, female
108.1
229_1
69 years, female
107.0
99_1
64 years, male
106.0
145_1
84 years, male
106.0
2_1
77 years, female
105.4
117_1
61 years, male
105.3
322_1
76 years, male
104.9
288_1
66 years, female
103.1
389_1
86 years, female
100.3
518_1
75 years, female
100.3
379_1
60 years, male
99.3
265_1
87 years, male
97.9
4_1
88 years, female
97.7
6_1
73 years, female
97.4
308_1
70 years, female
95.9
115_1
83 years, male
95.7
41_1
94 years, female
95.5
349_1
83 years, male
94.5
517_1
88 years, male
94.3
9_1
66 years, female
93.8
291_1
76 years, male
92.4
384_1
83 years, male
92.1
480_1
63 years, male
91.6
347_1
72 years, male
91.3
17_1
71 years, male
91.0
286_1
68 years, female
91.0
375_1
74 years, female
89.9
321_1
62 years, female
89.8
254_1
77 years, female
89.7
503_1
68 years, male
88.4
18_1
88 years, male
87.8
320_1
89 years, female
87.2
189_1
76 years, male
86.9
295_1
61 years, female
85.8
376_1
75 years, female
85.4
526_1
61 years, male
84.7
404_1
82 years, female
83.1
246_1
77 years, male
82.1
177_1
74 years, male
81.5
318_1
68 years, male
80.6
406_1
79 years, male
80.3
173_1
67 years, male
80.2
251_1
78 years, male
80.1
317_1
60 years, male
80.1
355_1
70 years, female
79.8
506_1
65 years, male
79.1
425_1
59 years, female
77.8
350_1
84 years, female
77.7
351_1
91 years, male
77.7
237_1
82 years, male
77.5
352_1
62 years, male
77.4
264_1
73 years, female
76.5
163_1
78 years, male
76.0
319_1
81 years, male
75.6
353_1
82 years, female
75.6
405_1
91 years, male
75.5
394_1
75 years, female
75.4
452_1
88 years, female
75.3
354_1
81 years, female
75.2
292_1
71 years, male
74.7
335_1
73 years, female
73.2
243_1
75 years, male
72.5
172_1
72 years, female
71.8
266_1
85 years, male
71.3
386_1
76 years, male
70.9
377_1
82 years, female
70.8
137_1
83 years, male
69.6
356_1
87 years, female
67.1
218_1
71 years, female
66.2
293_1
68 years, female
59.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
