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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:20794.2 nTPM
HPA:20794.2 nTPM
GTEx:12085.2 nTPM
Pig:7124.6 nTPM
Mouse:4168.5 nTPM
Allen mouse:21.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 20794.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 16959.5
2219 Male, age 76, both hemispheres 22478.7
2586 Male, age 75, left hemisphere 21971.5
2666 Male, age 74, left hemisphere 19606.6
2828 Female, age 72, unknown 18303.5
1833 Male, age 53, unknown 16628.1
1870 Female, age 42, unknown 15972.8
1830 Male, age 51, unknown 15945.2
1827 Male, age 72, unknown 13984.1
2019 Male, age 18, unknown 13064.1
2411 Female, age 72, unknown 11640.7
Dorsal raphe nucleus
nTPM: 13024.6
1828 Male, age 53, unknown 15538.9
2047 Male, age 72, unknown 14032.4
2750 Male, age 76, both hemispheres 13581.4
2016 Female, age 72, unknown 12113.1
2298 Female, age 72, unknown 9856.9
Inferior colliculus
nTPM: 15473.7
2849 Male, age 72, unknown 21687.6
1890 Male, age 53, unknown 15390.7
1848 Female, age 42, unknown 14106.3
2097 Female, age 72, unknown 10710.4
Median raphe nucleus
nTPM: 20794.2
2220 Male, age 76, midline 20794.2
Pedunculopontine tegmental nucleus
nTPM: 15996.5
2334 Male, age 80, both hemispheres 18391.3
2338 Male, age 61, both hemispheres 17428.0
1921 Female, age 85, both hemispheres 12170.2
Periaquaductal grey, anterior
nTPM: 12988.9
2502 Female, age 75, unknown 14233.0
1795 Male, age 51, unknown 12495.2
1947 Male, age 18, unknown 12238.6
Periaquaductal grey, dorsal
nTPM: 15762.3
2850 Male, age 76, both hemispheres 21820.8
1831 Male, age 72, unknown 14728.3
2464 Female, age 72, unknown 13557.8
1840 Male, age 53, unknown 12942.3
Periaquaductal grey, lateral
nTPM: 12515.1
2140 Male, age 76, both hemispheres 14275.1
2053 Male, age 18, unknown 12706.7
2272 Male, age 74, both hemispheres 10563.6
Pretectal area
nTPM: 15233.5
1816 Male, age 51, unknown 18591.1
1944 Female, age 72, unknown 18489.5
2667 Female, age 75, unknown 17965.0
1817 Female, age 42, unknown 17876.3
1815 Male, age 53, unknown 17464.1
2825 Male, age 18, unknown 15509.2
2007 Male, age 72, unknown 15380.5
2407 Male, age 75, both hemispheres 13535.0
2224 Female, age 72, unknown 11532.9
2316 Male, age 76, right hemisphere 10957.8
2273 Male, age 74, both hemispheres 10267.0
Red nucleus
nTPM: 16071.3
2584 Male, age 75, left hemisphere 19308.9
2588 Male, age 74, left hemisphere 18144.4
2823 Male, age 76, right hemisphere 17532.8
2503 Female, age 72, unknown 17472.6
1954 Female, age 42, unknown 16813.6
1865 Male, age 51, unknown 16230.9
2785 Male, age 18, unknown 15877.9
2227 Male, age 72, unknown 15029.6
1904 Male, age 53, unknown 14802.9
2769 Male, age 72, unknown 14764.9
2725 Female, age 75, unknown 13719.1
1821 Female, age 72, unknown 13157.6
Substantia nigra
nTPM: 16634.5
2665 Male, age 74, both hemispheres 24554.3
2699 Male, age 18, unknown 23404.7
1916 Female, age 42, unknown 17770.5
1941 Male, age 53, unknown 16427.2
2583 Male, age 75, right hemisphere 15531.7
1889 Female, age 72, unknown 14979.6
2590 Female, age 75, unknown 13793.0
2241 Male, age 72, unknown 13548.7
1851 Male, age 51, unknown 13378.3
2409 Female, age 72, unknown 12957.2
Superior colliculus
nTPM: 14932.6
2664 Male, age 75, both hemispheres 20466.3
2087 Female, age 72, unknown 16370.6
2587 Male, age 74, left hemisphere 15367.2
1913 Female, age 42, unknown 14995.5
2668 Female, age 75, unknown 14424.7
1839 Male, age 51, unknown 14250.6
1895 Male, age 76, right hemisphere 13948.3
1995 Male, age 72, unknown 13665.4
2261 Male, age 18, unknown 12985.9
1796 Male, age 53, unknown 12851.2
Ventral tegmental area
nTPM: 14932.5
2218 Male, age 76, both hemispheres 19343.9
2223 Female, age 72, unknown 16057.3
1942 Male, age 51, unknown 14874.6
1915 Female, age 42, unknown 13790.9
2021 Male, age 53, unknown 12914.7
2410 Female, age 72, unknown 12613.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 12085.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 12085.2
Samples: 139

Max nTPM: 50136.9
Min nTPM: 1802.7
Std nTPM: 9039.6
Median nTPM: 9427.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 50136.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 41606.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 40908.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 39542.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 39370.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 32832.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 31236.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 29656.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 28264.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 28039.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 26826.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 24732.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 24200.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 24040.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 23529.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 23491.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 23406.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 22685.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 22529.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 22081.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 22032.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 21857.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 21596.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 19276.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 18941.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 18224.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 18123.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 18089.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 17822.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 17706.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 17377.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 17181.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 16986.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 15594.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 15044.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 15022.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 14883.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 14524.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 13931.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 13824.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 13509.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 13295.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 13159.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 13053.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 12987.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 12922.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 12205.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 11895.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 11508.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 11470.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 11301.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 11195.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 11151.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10967.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 10924.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 10915.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 10900.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 10899.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 10826.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 10792.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 10569.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 10349.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 9879.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 9846.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 9737.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 9594.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 9561.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 9503.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 9492.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 9427.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 9319.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 9158.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 9003.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 8995.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 8918.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 8456.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 8326.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 7910.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 7749.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 7708.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 7421.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7361.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 7330.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 7312.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 7285.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 7259.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 7213.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 7070.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 7005.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 6996.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 6947.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 6918.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 6887.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 6845.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 6691.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 6529.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 6437.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 6297.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 5919.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 5879.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 5721.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 5710.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 5672.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 5672.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 5656.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 5495.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 5491.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 5470.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 5349.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 5282.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 5258.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 5249.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 5195.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 4994.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 4944.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 4842.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 4790.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 4730.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 4720.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 4657.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 4610.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 4535.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 4388.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 4342.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 4336.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 4203.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 4185.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 4149.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 3979.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 3976.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 3924.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 3674.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 3578.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 3511.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 3267.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 3067.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 2746.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2512.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1802.7
Show allShow less

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 7124.6
Pig sample Sample description nTPM
Midbrain
nTPM: 7124.6
Samples: 4

Max nTPM: 9663.0
Min nTPM: 5048.3
Sample A Female 6186.4
Sample B Female 9663.0
Sample C Male 7600.6
Sample D Male 5048.3
Periaqueductal gray
nTPM: 5316.8
Samples: 3

Max nTPM: 6100.1
Min nTPM: 4482.5
Sample B Female 5367.9
Sample C Male 6100.1
Sample D Male 4482.5
Substantia nigra
nTPM: 6274.7
Samples: 4

Max nTPM: 7949.6
Min nTPM: 3898.4
Sample A Female 7949.6
Sample B Female 5487.0
Sample C Male 7763.7
Sample D Male 3898.4
Superior colliculi
nTPM: 5702.4
Samples: 4

Max nTPM: 7270.6
Min nTPM: 1780.5
Sample A Female 6829.6
Sample B Female 1780.5
Sample C Male 7270.6
Sample D Male 6928.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 4168.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 4168.5
Samples: 4

Max nTPM: 4303.2
Min nTPM: 3915.1
Sample A Male 4303.2
Sample B Male 4293.8
Sample C Female 4162.0
Sample D Female 3915.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 21.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.6
75080269 Antisense, RP_060412_06_H09, Mouse strain C57BL/6J (56 days, male) 22.5
73906215 Antisense, RP_051212_04_H07, Mouse strain C57BL/6J (56 days, male) 20.8

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