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RPS18
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:1840.1 nTPM
HPA:1840.1 nTPM
GTEx:1794.2 nTPM
FANTOM5:102.6 Scaled Tags Per Million
Pig:320.2 nTPM
Mouse:646.4 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 1840.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1816.8
2666 Male, age 74, left hemisphere 1858.1
1870 Female, age 42, unknown 1843.1
2586 Male, age 75, left hemisphere 1842.1
2828 Female, age 72, unknown 1818.4
2411 Female, age 72, unknown 1816.6
1827 Male, age 72, unknown 1810.2
2019 Male, age 18, unknown 1803.9
1833 Male, age 53, unknown 1798.5
1830 Male, age 51, unknown 1796.9
2219 Male, age 76, both hemispheres 1779.6
Dorsal raphe nucleus
nTPM: 1814.1
2750 Male, age 76, both hemispheres 1833.8
2298 Female, age 72, unknown 1833.4
2016 Female, age 72, unknown 1823.1
1828 Male, age 53, unknown 1801.3
2047 Male, age 72, unknown 1778.7
Inferior colliculus
nTPM: 1804.8
1890 Male, age 53, unknown 1826.8
2097 Female, age 72, unknown 1811.5
2849 Male, age 72, unknown 1798.4
1848 Female, age 42, unknown 1782.3
Median raphe nucleus
nTPM: 1809.5
2220 Male, age 76, midline 1809.5
Pedunculopontine tegmental nucleus
nTPM: 1827.1
2338 Male, age 61, both hemispheres 1857.3
2334 Male, age 80, both hemispheres 1837.3
1921 Female, age 85, both hemispheres 1786.8
Periaquaductal grey, anterior
nTPM: 1819.9
2502 Female, age 75, unknown 1863.9
1795 Male, age 51, unknown 1802.5
1947 Male, age 18, unknown 1793.4
Periaquaductal grey, dorsal
nTPM: 1804.4
1840 Male, age 53, unknown 1833.7
2464 Female, age 72, unknown 1800.5
1831 Male, age 72, unknown 1799.5
2850 Male, age 76, both hemispheres 1784.1
Periaquaductal grey, lateral
nTPM: 1791.1
2053 Male, age 18, unknown 1814.8
2140 Male, age 76, both hemispheres 1796.3
2272 Male, age 74, both hemispheres 1762.1
Pretectal area
nTPM: 1801.8
2316 Male, age 76, right hemisphere 1835.4
2224 Female, age 72, unknown 1815.4
1817 Female, age 42, unknown 1814.8
2825 Male, age 18, unknown 1811.2
2007 Male, age 72, unknown 1810.4
1815 Male, age 53, unknown 1808.8
1816 Male, age 51, unknown 1793.5
1944 Female, age 72, unknown 1789.7
2667 Female, age 75, unknown 1789.0
2407 Male, age 75, both hemispheres 1788.1
2273 Male, age 74, both hemispheres 1763.4
Red nucleus
nTPM: 1839.5
2503 Female, age 72, unknown 1888.5
1865 Male, age 51, unknown 1867.2
1904 Male, age 53, unknown 1867.2
2227 Male, age 72, unknown 1848.9
1821 Female, age 72, unknown 1847.0
2584 Male, age 75, left hemisphere 1841.8
2769 Male, age 72, unknown 1832.2
2588 Male, age 74, left hemisphere 1828.0
2785 Male, age 18, unknown 1825.2
2725 Female, age 75, unknown 1824.6
1954 Female, age 42, unknown 1810.2
2823 Male, age 76, right hemisphere 1792.8
Substantia nigra
nTPM: 1840.1
1851 Male, age 51, unknown 1896.7
2665 Male, age 74, both hemispheres 1881.6
2699 Male, age 18, unknown 1880.2
2241 Male, age 72, unknown 1865.1
2409 Female, age 72, unknown 1847.2
1916 Female, age 42, unknown 1828.4
1889 Female, age 72, unknown 1815.3
2590 Female, age 75, unknown 1809.9
2583 Male, age 75, right hemisphere 1795.5
1941 Male, age 53, unknown 1781.2
Superior colliculus
nTPM: 1825.0
1913 Female, age 42, unknown 1870.2
2587 Male, age 74, left hemisphere 1864.5
1995 Male, age 72, unknown 1840.2
2668 Female, age 75, unknown 1834.6
1796 Male, age 53, unknown 1817.2
2664 Male, age 75, both hemispheres 1813.1
2087 Female, age 72, unknown 1807.4
1895 Male, age 76, right hemisphere 1802.7
1839 Male, age 51, unknown 1800.3
2261 Male, age 18, unknown 1799.6
Ventral tegmental area
nTPM: 1835.1
1915 Female, age 42, unknown 1870.5
2223 Female, age 72, unknown 1863.2
2021 Male, age 53, unknown 1842.6
1942 Male, age 51, unknown 1827.6
2410 Female, age 72, unknown 1814.5
2218 Male, age 76, both hemispheres 1792.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1794.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1794.2
Samples: 139

Max nTPM: 4615.7
Min nTPM: 614.0
Std nTPM: 738.5
Median nTPM: 1640.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4615.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4428.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4362.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 4109.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 4011.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3657.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 3264.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 3185.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2895.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2889.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2838.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2747.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2696.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2693.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2671.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2670.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2607.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2566.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2463.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2398.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 2385.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2348.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 2346.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2294.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 2291.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 2270.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 2265.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 2207.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 2196.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 2171.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2155.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2114.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 2108.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 2102.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2087.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 2082.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 2076.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 2071.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 2051.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2047.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 2038.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 2011.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 2000.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1977.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1967.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1952.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1931.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1930.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1910.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1881.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1874.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1860.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1849.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1824.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1814.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1808.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1803.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1794.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1793.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1747.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1725.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1725.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1707.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1705.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1702.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1688.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1666.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1646.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1644.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1640.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1633.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1619.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1610.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1602.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1582.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1577.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1575.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1563.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1551.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1537.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1531.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1509.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1480.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1475.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1463.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1460.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1457.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1454.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1438.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1423.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1416.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1407.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1368.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1368.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1367.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1358.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1355.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1354.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1354.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1353.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1350.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1333.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1326.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1325.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1313.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1305.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1301.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1270.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1267.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1240.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1222.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1221.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1220.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1218.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1212.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1201.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1196.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1168.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1141.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1140.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1127.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1092.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1079.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1079.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1065.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1064.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1036.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1027.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1007.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 973.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 948.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 942.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 891.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 857.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 847.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 829.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 823.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 782.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 614.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 102.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 102.6
FF:10158-103A5 76 years, female 102.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 320.2
Pig sample Sample description nTPM
Midbrain
nTPM: 302.4
Samples: 4

Max nTPM: 445.1
Min nTPM: 185.9
Sample A Female 445.1
Sample B Female 321.1
Sample C Male 257.4
Sample D Male 185.9
Periaqueductal gray
nTPM: 233.2
Samples: 3

Max nTPM: 256.7
Min nTPM: 203.0
Sample B Female 256.7
Sample C Male 239.9
Sample D Male 203.0
Substantia nigra
nTPM: 308.9
Samples: 4

Max nTPM: 419.4
Min nTPM: 236.8
Sample A Female 419.4
Sample B Female 333.6
Sample C Male 236.8
Sample D Male 245.8
Superior colliculi
nTPM: 320.2
Samples: 4

Max nTPM: 389.9
Min nTPM: 260.5
Sample A Female 389.9
Sample B Female 345.2
Sample C Male 285.1
Sample D Male 260.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 646.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 646.4
Samples: 4

Max nTPM: 699.7
Min nTPM: 584.2
Sample A Male 699.7
Sample B Male 610.0
Sample C Female 584.2
Sample D Female 691.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
69873283 Antisense, RP_050510_04_H10, Mouse strain C57BL/6J (56 days, male) 3.1

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