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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Ventrolateral medulla, A1-C1 cell groups nTPM: 41.0
1986
Male, age 76, both hemispheres
43.3
2741
Female, age 85, both hemispheres
42.7
2180
Male, age 61, both hemispheres
42.0
2302
Female, age 91, both hemispheres
39.2
2118
Male, age 80, both hemispheres
37.6
Ventrolateral tegmental area, A5 NE cell group nTPM: 39.0
1959
Male, age 76, both hemispheres
41.7
2456
Female, age 91, both hemispheres
40.0
2161
Male, age 80, both hemispheres
39.5
2449
Male, age 74, both hemispheres
39.0
2840
Female, age 85, both hemispheres
37.7
2359
Male, age 61, both hemispheres
36.1
PONS AND MEDULLA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.