In this movie Professor Tomas Hökfelt (Karolinska Institutet) takes you on a journey to the areas of the brain affected by Alzheimer's disease.

He shows how amyloid plaques and tau tangles, disrupt and kill neurons leading to loss of cognitive functions. He also illustrates how the use of volume imaging methods (Dr. Csaba Adori, Karolinska Institutet) provide new insights in how the disease starts and progresses. Based on these results the patterns in how the disease spreads have now been revealed, which was published recently in Acta Neuropathologica. Understanding these patterns will provide the answers on what happens in Alzheimer´s disease.

Link to movie

Link to short version movie