In a correspondence in Nature Medicine an initiative with the aim to connect research with healthcare and establish Sweden as a major player in the field of data-driven precision medicine was presented...Read more

In 2021, Trey Idekers team at UCLA in collaboration with Emma Lundbergs team at KTH and Stanford presented a new way of creating hierarchical maps of subcellular protein organization by integrating data from immunofluorescence images from the HPA with protein interaction data. The resulting cell map was referred to as the multi-scale integrated cell (MuSIC 1.0). Four years later, the same team has now released the next version of such a multimodal cell map, again accompanied by a prestigious publication in Nature...Read more

In a publication in the journal Neuron a group of scientists including Jan Mulder, an HPA-related researcher, have used Stereo-seq, in combination with single-nucleus RNA sequencing data to create a 3-D atlas showing the cell-type distribution across the whole mouse brain. The spatial distributions of diverse cell types and lncRNAs in adult brain as well as the spatiotemporal profile of gene expression during brain development were investigated...Read more

KTH professor Mathias Uhlén, founder of the Human Protein Atlas, was interviewed in GenomeWeb about the new Alpha Cell project, an effort with the aim to map and model cellular components and processes...Read more

Since the release of HPA v24, we are providing a unique highly-multiplexed data set showing the distribution of a large set of reference markers across all major tissues and organs in the human body. The images have been generated using CODEX technology for simultaneous immunostaining of 47 marker proteins across the panel of normal HPA tissue microarrays. The markers have been selected to help distinguish different tissue structures and cell types, and thus histological features, in the TMAs...Read more