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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:460.4 nTPM
HPA:460.4 nTPM
GTEx:455.0 nTPM
FANTOM5:21.2 Scaled Tags Per Million
Pig:343.0 nTPM
Mouse:840.3 nTPM
Allen mouse:20.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 460.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 416.7
2019 Male, age 18, unknown 449.8
1827 Male, age 72, unknown 434.0
2411 Female, age 72, unknown 427.9
2666 Male, age 74, left hemisphere 426.2
2586 Male, age 75, left hemisphere 418.7
2219 Male, age 76, both hemispheres 418.6
2828 Female, age 72, unknown 413.3
1870 Female, age 42, unknown 399.7
1833 Male, age 53, unknown 393.6
1830 Male, age 51, unknown 384.6
Dorsal raphe nucleus
nTPM: 417.3
2298 Female, age 72, unknown 450.8
1828 Male, age 53, unknown 426.9
2047 Male, age 72, unknown 415.3
2750 Male, age 76, both hemispheres 413.3
2016 Female, age 72, unknown 380.2
Inferior colliculus
nTPM: 410.8
2097 Female, age 72, unknown 445.2
1890 Male, age 53, unknown 416.8
1848 Female, age 42, unknown 398.1
2849 Male, age 72, unknown 382.9
Median raphe nucleus
nTPM: 432.2
2220 Male, age 76, midline 432.2
Pedunculopontine tegmental nucleus
nTPM: 428.0
1921 Female, age 85, both hemispheres 434.5
2334 Male, age 80, both hemispheres 432.6
2338 Male, age 61, both hemispheres 416.8
Periaquaductal grey, anterior
nTPM: 421.0
1795 Male, age 51, unknown 436.2
1947 Male, age 18, unknown 414.7
2502 Female, age 75, unknown 412.0
Periaquaductal grey, dorsal
nTPM: 396.5
1831 Male, age 72, unknown 400.4
2464 Female, age 72, unknown 398.0
2850 Male, age 76, both hemispheres 394.1
1840 Male, age 53, unknown 393.7
Periaquaductal grey, lateral
nTPM: 390.1
2272 Male, age 74, both hemispheres 394.3
2053 Male, age 18, unknown 389.1
2140 Male, age 76, both hemispheres 386.9
Pretectal area
nTPM: 460.4
1816 Male, age 51, unknown 561.6
1944 Female, age 72, unknown 535.4
1817 Female, age 42, unknown 522.8
2007 Male, age 72, unknown 503.7
1815 Male, age 53, unknown 472.7
2667 Female, age 75, unknown 468.6
2224 Female, age 72, unknown 415.5
2273 Male, age 74, both hemispheres 404.4
2316 Male, age 76, right hemisphere 397.3
2825 Male, age 18, unknown 396.4
2407 Male, age 75, both hemispheres 385.6
Red nucleus
nTPM: 415.7
2785 Male, age 18, unknown 447.1
1821 Female, age 72, unknown 442.1
2725 Female, age 75, unknown 421.8
2588 Male, age 74, left hemisphere 418.4
2503 Female, age 72, unknown 415.0
1954 Female, age 42, unknown 414.3
1865 Male, age 51, unknown 410.8
2823 Male, age 76, right hemisphere 409.9
1904 Male, age 53, unknown 407.5
2769 Male, age 72, unknown 406.0
2227 Male, age 72, unknown 405.6
2584 Male, age 75, left hemisphere 389.5
Substantia nigra
nTPM: 440.4
1916 Female, age 42, unknown 487.6
1889 Female, age 72, unknown 484.7
2665 Male, age 74, both hemispheres 451.3
1851 Male, age 51, unknown 450.2
2241 Male, age 72, unknown 448.6
1941 Male, age 53, unknown 443.9
2409 Female, age 72, unknown 428.3
2590 Female, age 75, unknown 406.1
2699 Male, age 18, unknown 405.5
2583 Male, age 75, right hemisphere 397.7
Superior colliculus
nTPM: 424.2
2087 Female, age 72, unknown 509.2
2261 Male, age 18, unknown 452.8
2668 Female, age 75, unknown 438.4
1796 Male, age 53, unknown 437.2
1913 Female, age 42, unknown 420.5
2587 Male, age 74, left hemisphere 406.8
1895 Male, age 76, right hemisphere 404.3
1995 Male, age 72, unknown 402.0
1839 Male, age 51, unknown 389.3
2664 Male, age 75, both hemispheres 381.8
Ventral tegmental area
nTPM: 424.3
2410 Female, age 72, unknown 444.4
1915 Female, age 42, unknown 443.2
2218 Male, age 76, both hemispheres 435.9
2223 Female, age 72, unknown 415.4
1942 Male, age 51, unknown 407.0
2021 Male, age 53, unknown 400.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 455.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 455.0
Samples: 139

Max nTPM: 911.8
Min nTPM: 216.4
Std nTPM: 147.4
Median nTPM: 425.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 911.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 900.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 841.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 839.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 824.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 755.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 745.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 738.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 717.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 692.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 680.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 670.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 654.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 654.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 648.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 637.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 633.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 631.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 630.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 630.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 626.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 622.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 620.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 617.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 613.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 602.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 595.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 588.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 583.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 578.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 576.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 565.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 552.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 542.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 533.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 531.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 530.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 520.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 518.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 512.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 512.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 491.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 489.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 489.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 486.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 484.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 484.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 482.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 476.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 471.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 470.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 470.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 469.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 468.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 466.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 458.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 457.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 457.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 448.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 443.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 442.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 439.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 436.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 434.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 433.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 433.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 430.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 429.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 429.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 425.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 425.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 424.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 422.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 414.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 411.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 411.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 410.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 407.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 399.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 395.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 394.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 393.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 393.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 392.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 389.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 388.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 388.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 387.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 387.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 383.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 383.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 382.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 380.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 379.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 376.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 376.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 375.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 372.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 371.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 370.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 367.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 366.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 366.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 364.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 357.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 351.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 349.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 347.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 344.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 344.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 338.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 330.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 326.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 326.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 325.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 321.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 312.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 311.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 306.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 301.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 300.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 295.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 288.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 286.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 284.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 283.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 282.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 281.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 274.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 271.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 269.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 266.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 254.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 240.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 231.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 230.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 226.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 226.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 216.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 21.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 21.2
FF:10158-103A5 76 years, female 21.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 343.0
Pig sample Sample description nTPM
Midbrain
nTPM: 306.2
Samples: 4

Max nTPM: 394.6
Min nTPM: 241.7
Sample A Female 241.7
Sample B Female 276.4
Sample C Male 394.6
Sample D Male 312.0
Periaqueductal gray
nTPM: 249.5
Samples: 3

Max nTPM: 294.1
Min nTPM: 211.2
Sample B Female 243.2
Sample C Male 294.1
Sample D Male 211.2
Substantia nigra
nTPM: 271.2
Samples: 4

Max nTPM: 366.2
Min nTPM: 182.2
Sample A Female 366.2
Sample B Female 209.5
Sample C Male 326.8
Sample D Male 182.2
Superior colliculi
nTPM: 343.1
Samples: 4

Max nTPM: 429.3
Min nTPM: 235.3
Sample A Female 381.6
Sample B Female 235.3
Sample C Male 429.3
Sample D Male 326.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 840.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 840.3
Samples: 4

Max nTPM: 884.5
Min nTPM: 805.1
Sample A Male 833.9
Sample B Male 837.6
Sample C Female 805.1
Sample D Female 884.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 20.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 20.2
70191997 Antisense, RP_050517_01_A08, Mouse strain C57BL/6J (56 days, male) 20.2

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