Expression of RPS12 in testis cancer - The Human Protein Atlas

TESTIS CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

RPS12 is not prognostic in testis cancer

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 1700.02

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1566.1

Number of samples

134

Samples

Sample	Description	FPKM
TCGA-2G-AAHL-01A	26 years, male, white, stage:i, alive, 7081 days	3752.8
TCGA-SN-A84X-01A	21 years, male, white, stage:is, alive, 312 days	3358.8
TCGA-2G-AAFN-01A	26 years, male, white, stage:iiib, alive, 773 days	2705.9
TCGA-VF-A8AA-01A	51 years, male, white, stage:i, alive, 1146 days	2630.4
TCGA-XE-AANR-01A	24 years, male, white, stage:i, alive, 14 days	2599.4
TCGA-2G-AAGW-01A	38 years, male, white, stage:is, alive, 4899 days	2545.2
TCGA-2G-AAFO-01A	33 years, male, white, stage:iia, alive, 685 days	2474.9
TCGA-2G-AAKD-01A	18 years, male, white, stage:iii, alive, 6340 days	2435.6
TCGA-WZ-A7V5-01A	27 years, male, white, stage:i, alive, 1061 days	2308.0
TCGA-4K-AAAL-01A	31 years, male, white, stage:is, alive, 483 days	2266.5
TCGA-SN-A84Y-01A	18 years, male, white, stage:is, alive, 524 days	2261.5
TCGA-VF-A8AE-01A	39 years, male, white, stage:ia, alive, 727 days	2259.7
TCGA-VF-A8AC-01A	29 years, male, white, stage:ia, alive, 1083 days	2220.5
TCGA-2G-AAGA-01A	38 years, male, white, stage:iia, alive, 2439 days	2165.0
TCGA-2G-AAFL-01A	35 years, male, white, stage:ib, alive, 750 days	2163.1
TCGA-2G-AAFM-01A	31 years, male, white, stage:iia, alive, 503 days	2162.6
TCGA-2G-AAL7-01A	32 years, male, white, stage:is, alive, 3991 days	2157.9
TCGA-2G-AAH3-01A	20 years, male, white, stage:i, alive, 1822 days	2103.1
TCGA-SB-A76C-01A	38 years, male, white, alive, 42 days	2084.8
TCGA-2G-AAGO-01A	41 years, male, white, stage:is, alive, 4026 days	2073.5
TCGA-SO-A8JP-01A	29 years, male, white, stage:i, alive, 540 days	2068.2
TCGA-2G-AAGF-01A	28 years, male, white, stage:is, alive, 2734 days	2040.0
TCGA-2G-AAG9-01A	25 years, male, white, stage:iiib, alive, 2234 days	2013.5
TCGA-2G-AAEX-01A	38 years, male, white, stage:is, alive, 1259 days	1993.7
TCGA-SN-A6IS-01A	26 years, male, white, stage:is, alive, 496 days	1987.5
TCGA-VF-A8A9-01A	31 years, male, white, stage:ia, alive, 1119 days	1982.0
TCGA-2G-AAL5-01A	31 years, male, white, stage:i, alive, 7437 days	1979.7
TCGA-WZ-A8D5-01A	38 years, male, white, alive, 774 days	1976.6
TCGA-S6-A8JX-01A	27 years, male, white, stage:ib, alive, 552 days	1973.1
TCGA-2G-AAH8-01A	45 years, male, white, stage:iiic, alive, 2248 days	1950.8
TCGA-2G-AAG8-01A	21 years, male, white, stage:ib, alive, 2289 days	1949.2
TCGA-2G-AAKG-01A	22 years, male, white, stage:i, alive, 6598 days	1940.4
TCGA-SB-A6J6-01A	22 years, male, white, stage:ia, alive, 413 days	1899.8
TCGA-2G-AAF6-01A	28 years, male, white, stage:is, alive, 3491 days	1899.4
TCGA-WZ-A7V3-01A	20 years, male, white, stage:i, alive, 753 days	1897.3
TCGA-XY-A8S2-01A	67 years, male, white, stage:i, alive, 672 days	1892.0
TCGA-ZM-AA06-01A	45 years, male, white, stage:ib, alive, 1498 days	1890.8
TCGA-2G-AAGZ-01A	27 years, male, white, stage:iiia, alive, 5233 days	1854.5
TCGA-2G-AAFH-01A	38 years, male, white, stage:iib, alive, 1375 days	1854.2
TCGA-2G-AAGJ-01A	28 years, male, black or african american, stage:ia, alive, 2938 days	1853.7
TCGA-XY-A89B-01A	35 years, male, white, stage:ia, alive, 471 days	1818.5
TCGA-2G-AAF8-01A	33 years, male, white, stage:ia, alive, 3911 days	1799.4
TCGA-XE-AANV-01A	52 years, male, stage:ib, alive, 1701 days	1773.6
TCGA-XE-A9SE-01A	35 years, male, white, stage:ia, alive, 708 days	1742.2
TCGA-2G-AAHP-01A	31 years, male, white, stage:is, alive, 5667 days	1726.1
TCGA-VF-A8AB-01A	31 years, male, black or african american, stage:ia, alive, 760 days	1722.6
TCGA-YU-A90W-01A	45 years, male, white, stage:ia, alive, 1113 days	1718.1
TCGA-W4-A7U2-01A	26 years, male, white, alive, 1263 days	1700.2
TCGA-2G-AAEW-01A	31 years, male, white, stage:is, dead, 618 days	1699.9
TCGA-XE-AAO4-01A	40 years, male, white, stage:ia, alive, 367 days	1673.6
TCGA-2G-AAGS-01A	39 years, male, white, stage:iiib, alive, 4816 days	1673.4
TCGA-2G-AAGN-01A	41 years, male, white, stage:iiib, alive, 3656 days	1660.9
TCGA-XE-AANJ-01A	39 years, male, white, stage:is, alive, 2007 days	1654.7
TCGA-SN-A84W-01A	30 years, male, white, stage:is, alive, 293 days	1644.2
TCGA-4K-AA1I-01A	26 years, male, white, stage:ia, alive, 3 days	1643.9
TCGA-2G-AAKM-01A	14 years, male, white, stage:ii, dead, 6972 days	1640.1
TCGA-YU-A912-01A	34 years, male, black or african american, stage:iiic, alive, 866 days	1631.2
TCGA-XE-AAOD-01A	39 years, male, white, stage:ib, alive, 2058 days	1628.7
TCGA-YU-A90Q-01A	21 years, male, stage:ib, alive, 1964 days	1600.8
TCGA-2G-AAF1-01A	28 years, male, asian, stage:is, alive, 1403 days	1597.5
TCGA-2G-AAH0-01A	30 years, male, white, stage:is, alive, 5477 days	1575.6
TCGA-2G-AAH4-01A	34 years, male, white, stage:ii, alive, 6210 days	1573.9
TCGA-2G-AAHN-01A	32 years, male, white, stage:i, alive, 6445 days	1560.5
TCGA-XY-A9T9-01A	37 years, male, white, stage:is, alive, 281 days	1551.5
TCGA-2G-AAFG-01A	30 years, male, white, stage:is, alive, 6183 days	1532.9
TCGA-2G-AAF4-01A	30 years, male, white, stage:i, alive, 2315 days	1532.8
TCGA-2G-AAFJ-01A	23 years, male, asian, alive, 792 days	1532.4
TCGA-XE-AAOB-01A	27 years, male, white, stage:is, dead, 513 days	1516.3
TCGA-XE-AAOJ-01A	24 years, male, white, stage:is, alive, 1550 days	1466.2
TCGA-VF-A8A8-01A	18 years, male, white, stage:ia, alive, 1131 days	1455.7
TCGA-2G-AAG0-01A	23 years, male, white, stage:is, alive, 1529 days	1441.0
TCGA-2G-AAGE-01A	21 years, male, white, stage:is, alive, 2478 days	1434.5
TCGA-2G-AAFI-01A	41 years, male, white, stage:ib, alive, 675 days	1434.4
TCGA-4K-AA1H-01A	26 years, male, white, stage:ia, alive, 518 days	1430.7
TCGA-2G-AAHT-01A	32 years, male, white, stage:is, alive, 542 days	1424.4
TCGA-2G-AAFY-01A	24 years, male, white, stage:iia, alive, 1099 days	1405.0
TCGA-ZM-AA0D-01A	34 years, male, white, stage:ia, alive, 848 days	1389.4
TCGA-2G-AAKL-01A	26 years, male, white, stage:ii, alive, 7023 days	1381.1
TCGA-2G-AAGT-01A	30 years, male, white, stage:is, alive, 4406 days	1379.6
TCGA-VF-A8AD-01A	36 years, male, white, stage:ib, alive, 1006 days	1358.7
TCGA-2G-AAKH-01A	19 years, male, white, stage:ii, alive, 6862 days	1355.0
TCGA-XE-AANI-01A	37 years, male, white, stage:is, alive, 1041 days	1342.2
TCGA-YU-A94D-01A	28 years, male, stage:iiib, alive, 2167 days	1341.8
TCGA-2G-AAGV-01A	23 years, male, white, alive, 4527 days	1333.5
TCGA-2G-AAGX-01A	22 years, male, white, stage:ia, alive, 5514 days	1325.5
TCGA-XE-AAO3-01A	33 years, male, asian, stage:i, alive, 2857 days	1324.4
TCGA-XE-AAO6-01A	47 years, male, white, stage:ia, alive, 240 days	1321.0
TCGA-2G-AAG3-01A	53 years, male, white, stage:is, alive, 1593 days	1317.9
TCGA-XE-A8H4-01A	23 years, male, white, stage:ia, alive, 559 days	1316.2
TCGA-4K-AA1G-01A	34 years, male, white, stage:is, alive, 436 days	1313.9
TCGA-W4-A7U4-01A	23 years, male, white, alive, 738 days	1313.4
TCGA-XY-A8S3-01B	24 years, male, white, stage:is, alive, 843 days	1299.0
TCGA-2G-AAH2-01A	20 years, male, white, stage:is, alive, 6060 days	1295.5
TCGA-2G-AAGG-01A	20 years, male, white, stage:iiic, alive, 2611 days	1293.7
TCGA-2X-A9D6-01A	42 years, male, white, stage:i, alive, 607 days	1291.5
TCGA-X3-A8G4-01A	33 years, male, white, stage:is, alive, 856 days	1290.8
TCGA-YU-A90Y-01A	23 years, male, black or african american, stage:iiic, dead, 17 days	1288.5
TCGA-2G-AAFE-01A	37 years, male, white, stage:iia, alive, 4702 days	1285.6
TCGA-2G-AALP-01A	43 years, male, white, stage:iiib, alive, 2645 days	1284.4
TCGA-ZM-AA0B-01A	32 years, male, white, stage:ia, alive, 838 days	1277.6
TCGA-XE-AAOF-01A	50 years, male, asian, stage:ia, alive, 1268 days	1270.9
TCGA-2G-AAHG-01A	25 years, male, white, stage:i, alive, 1819 days	1268.2
TCGA-WZ-A7V4-01A	28 years, male, white, stage:i, alive, 894 days	1248.0
TCGA-2G-AAGC-01A	28 years, male, white, stage:is, alive, 2585 days	1217.1
TCGA-S6-A8JW-01A	37 years, male, white, stage:is, alive, 698 days	1204.8
TCGA-XE-A8H5-01A	29 years, male, stage:is, alive, 1217 days	1152.4
TCGA-YU-A90S-01A	26 years, male, white, stage:ia, alive, 971 days	1131.7
TCGA-XE-A8H1-01A	24 years, male, white, stage:is, alive, 209 days	1130.8
TCGA-2G-AAG7-01A	33 years, male, white, stage:is, alive, 2475 days	1123.2
TCGA-2G-AAFZ-01A	32 years, male, white, stage:iii, alive, 1353 days	1122.4
TCGA-S6-A8JY-01A	27 years, male, white, stage:is, alive, 278 days	1115.3
TCGA-2G-AAGI-01A	33 years, male, white, stage:is, alive, 3137 days	1089.9
TCGA-YU-AA61-01A	29 years, male, white, stage:is, alive, 864 days	1056.0
TCGA-2G-AAHC-01A	33 years, male, white, stage:is, alive, 5539 days	1048.1
TCGA-2G-AAGK-01A	20 years, male, white, stage:is, alive, 3621 days	1032.4
TCGA-XE-AAOC-01A	31 years, male, white, stage:ia, alive, 270 days	1028.3
TCGA-ZM-AA0E-01A	39 years, male, white, stage:ia, alive, 811 days	994.1
TCGA-2G-AAGY-01A	28 years, male, white, stage:is, alive, 5329 days	992.0
TCGA-2G-AAGM-01A	51 years, male, white, stage:is, alive, 3891 days	991.6
TCGA-XE-AAOL-01A	38 years, male, black or african american, stage:i, alive, 13 days	984.3
TCGA-YU-A90P-01A	25 years, male, white, stage:ia, alive, 2069 days	961.1
TCGA-2G-AAG6-01A	24 years, male, white, stage:is, alive, 2231 days	953.0
TCGA-2G-AAHA-01A	48 years, male, white, stage:ib, alive, 3349 days	933.8
TCGA-W4-A7U3-01A	26 years, male, white, alive, 149 days	873.3
TCGA-YU-AA4L-01A	27 years, male, black or african american, stage:iiic, alive, 1573 days	870.4
TCGA-ZM-AA0H-01A	50 years, male, white, stage:is, alive, 1736 days	846.1
TCGA-2X-A9D5-01A	49 years, male, white, stage:i, alive, 435 days	827.9
TCGA-2G-AAG5-01A	36 years, male, white, stage:is, alive, 2299 days	726.8
TCGA-2G-AAGP-01A	33 years, male, white, stage:iia, alive, 4018 days	711.4
TCGA-ZM-AA0F-01A	35 years, male, white, stage:ia, alive, 681 days	703.3
TCGA-YU-A94I-01A	66 years, male, stage:ia, alive, 536 days	651.1
TCGA-ZM-AA0N-01A	44 years, male, white, stage:ib, alive, 634 days	637.5
TCGA-2G-AAFV-01A	31 years, male, white, stage:is, alive, 1389 days	563.5
TCGA-ZM-AA05-01A	36 years, male, white, stage:iic, alive, 1126 days	434.9
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TESTIS CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample. Read more	Antibody HPA006124
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details