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RPS15
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:1079.2 nTPM
HPA:1079.2 nTPM
GTEx:1383.4 nTPM
FANTOM5:54.1 Scaled Tags Per Million
Pig:310.0 nTPM
Mouse:1260.1 nTPM
Allen mouse:5.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 1079.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1067.0
2586 Male, age 75, left hemisphere 1152.3
2828 Female, age 72, unknown 1082.8
2666 Male, age 74, left hemisphere 1077.6
1870 Female, age 42, unknown 1069.2
2019 Male, age 18, unknown 1060.9
1833 Male, age 53, unknown 1050.6
1830 Male, age 51, unknown 1049.3
2411 Female, age 72, unknown 1048.6
1827 Male, age 72, unknown 1048.0
2219 Male, age 76, both hemispheres 1030.7
Dorsal raphe nucleus
nTPM: 1048.6
2750 Male, age 76, both hemispheres 1072.8
2298 Female, age 72, unknown 1062.6
2016 Female, age 72, unknown 1046.2
1828 Male, age 53, unknown 1034.2
2047 Male, age 72, unknown 1027.3
Inferior colliculus
nTPM: 1050.0
1890 Male, age 53, unknown 1062.3
2849 Male, age 72, unknown 1060.5
1848 Female, age 42, unknown 1041.8
2097 Female, age 72, unknown 1035.3
Median raphe nucleus
nTPM: 1049.8
2220 Male, age 76, midline 1049.8
Pedunculopontine tegmental nucleus
nTPM: 1066.5
2338 Male, age 61, both hemispheres 1089.4
2334 Male, age 80, both hemispheres 1085.0
1921 Female, age 85, both hemispheres 1025.0
Periaquaductal grey, anterior
nTPM: 1072.4
2502 Female, age 75, unknown 1103.6
1795 Male, age 51, unknown 1071.9
1947 Male, age 18, unknown 1041.5
Periaquaductal grey, dorsal
nTPM: 1037.1
1840 Male, age 53, unknown 1058.5
2850 Male, age 76, both hemispheres 1041.1
1831 Male, age 72, unknown 1031.6
2464 Female, age 72, unknown 1017.2
Periaquaductal grey, lateral
nTPM: 1030.9
2053 Male, age 18, unknown 1038.7
2140 Male, age 76, both hemispheres 1029.5
2272 Male, age 74, both hemispheres 1024.5
Pretectal area
nTPM: 1047.8
2007 Male, age 72, unknown 1084.0
1817 Female, age 42, unknown 1077.4
1816 Male, age 51, unknown 1067.3
1815 Male, age 53, unknown 1054.6
2316 Male, age 76, right hemisphere 1052.5
1944 Female, age 72, unknown 1051.9
2825 Male, age 18, unknown 1037.9
2224 Female, age 72, unknown 1037.2
2407 Male, age 75, both hemispheres 1027.3
2273 Male, age 74, both hemispheres 1021.2
2667 Female, age 75, unknown 1014.4
Red nucleus
nTPM: 1079.2
2503 Female, age 72, unknown 1153.0
2769 Male, age 72, unknown 1094.8
2227 Male, age 72, unknown 1090.1
2584 Male, age 75, left hemisphere 1085.4
2785 Male, age 18, unknown 1084.1
2725 Female, age 75, unknown 1081.5
2588 Male, age 74, left hemisphere 1079.1
1865 Male, age 51, unknown 1076.5
1904 Male, age 53, unknown 1060.1
1821 Female, age 72, unknown 1051.9
2823 Male, age 76, right hemisphere 1048.1
1954 Female, age 42, unknown 1046.2
Substantia nigra
nTPM: 1063.8
2699 Male, age 18, unknown 1102.2
1851 Male, age 51, unknown 1098.6
2665 Male, age 74, both hemispheres 1077.4
1916 Female, age 42, unknown 1067.9
2583 Male, age 75, right hemisphere 1067.9
1889 Female, age 72, unknown 1067.1
2590 Female, age 75, unknown 1065.1
2409 Female, age 72, unknown 1043.1
1941 Male, age 53, unknown 1040.9
2241 Male, age 72, unknown 1007.5
Superior colliculus
nTPM: 1068.6
2587 Male, age 74, left hemisphere 1112.6
1995 Male, age 72, unknown 1103.8
1796 Male, age 53, unknown 1092.8
1913 Female, age 42, unknown 1077.9
2668 Female, age 75, unknown 1068.5
2664 Male, age 75, both hemispheres 1066.9
2261 Male, age 18, unknown 1059.6
1839 Male, age 51, unknown 1045.2
2087 Female, age 72, unknown 1043.6
1895 Male, age 76, right hemisphere 1014.8
Ventral tegmental area
nTPM: 1064.3
1915 Female, age 42, unknown 1088.2
2223 Female, age 72, unknown 1073.9
2021 Male, age 53, unknown 1064.8
2410 Female, age 72, unknown 1061.3
2218 Male, age 76, both hemispheres 1049.2
1942 Male, age 51, unknown 1048.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1383.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1383.4
Samples: 139

Max nTPM: 4545.9
Min nTPM: 520.3
Std nTPM: 564.6
Median nTPM: 1259.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4545.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3021.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2904.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2899.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2859.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2654.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2621.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2450.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2390.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2242.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2176.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2133.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2060.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2051.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1976.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1956.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1923.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1824.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1798.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1783.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1766.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1736.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1731.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1720.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1709.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1703.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1697.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1688.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1680.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1673.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1657.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1651.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1647.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1637.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1611.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1609.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1591.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1586.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1574.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1563.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1562.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1560.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1558.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1558.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1552.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1542.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1535.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1527.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1511.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1511.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1494.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1483.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1480.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1466.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1440.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1438.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1438.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1436.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1378.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1372.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1369.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1356.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1351.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1349.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1342.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1337.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1325.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1318.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1285.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1259.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1256.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1226.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1222.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1221.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1213.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1206.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1201.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1197.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1191.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1184.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1183.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1177.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1142.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1138.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1136.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1134.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1105.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1083.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1076.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1073.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1069.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1067.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1058.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1057.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1047.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1045.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1044.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1043.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1033.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1024.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1007.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1006.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1006.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 993.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 992.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 988.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 977.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 975.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 973.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 964.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 957.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 955.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 952.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 948.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 944.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 942.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 939.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 932.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 927.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 926.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 926.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 892.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 876.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 873.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 852.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 847.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 844.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 837.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 836.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 794.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 779.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 750.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 747.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 702.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 663.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 619.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 570.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 529.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 520.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 54.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 54.1
FF:10158-103A5 76 years, female 54.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 310.0
Pig sample Sample description nTPM
Midbrain
nTPM: 292.4
Samples: 4

Max nTPM: 428.6
Min nTPM: 201.8
Sample A Female 428.6
Sample B Female 308.8
Sample C Male 230.3
Sample D Male 201.8
Periaqueductal gray
nTPM: 225.6
Samples: 3

Max nTPM: 252.2
Min nTPM: 205.0
Sample B Female 219.6
Sample C Male 252.2
Sample D Male 205.0
Substantia nigra
nTPM: 310.0
Samples: 4

Max nTPM: 397.6
Min nTPM: 261.8
Sample A Female 397.6
Sample B Female 312.3
Sample C Male 261.8
Sample D Male 268.3
Superior colliculi
nTPM: 306.3
Samples: 4

Max nTPM: 364.3
Min nTPM: 254.0
Sample A Female 364.3
Sample B Female 346.7
Sample C Male 254.0
Sample D Male 260.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1260.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 1260.1
Samples: 4

Max nTPM: 1442.1
Min nTPM: 1097.0
Sample A Male 1442.1
Sample B Male 1161.7
Sample C Female 1097.0
Sample D Female 1339.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 5.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.2
75774687 Antisense, RP_060530_01_D12, Mouse strain C57BL/6J (56 days, male) 6.9
68321982 Antisense, RP_041207_01_B08, Mouse strain C57BL/6J (56 days, male) 3.5

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.