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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:706.3 nTPM
HPA:706.3 nTPM
GTEx:708.1 nTPM
FANTOM5:655.7 Scaled Tags Per Million
Pig:83.6 nTPM
Mouse:357.8 nTPM
Allen mouse:4.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 706.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 647.6
2411 Female, age 72, unknown 693.1
1870 Female, age 42, unknown 683.7
2828 Female, age 72, unknown 678.0
1833 Male, age 53, unknown 658.3
1827 Male, age 72, unknown 657.5
1830 Male, age 51, unknown 644.5
2019 Male, age 18, unknown 635.7
2219 Male, age 76, both hemispheres 626.3
2586 Male, age 75, left hemisphere 602.0
2666 Male, age 74, left hemisphere 596.9
Dorsal raphe nucleus
nTPM: 706.3
2298 Female, age 72, unknown 738.8
2016 Female, age 72, unknown 704.6
2047 Male, age 72, unknown 699.7
2750 Male, age 76, both hemispheres 699.5
1828 Male, age 53, unknown 689.0
Inferior colliculus
nTPM: 670.3
2097 Female, age 72, unknown 694.4
1848 Female, age 42, unknown 692.3
2849 Male, age 72, unknown 649.0
1890 Male, age 53, unknown 645.5
Median raphe nucleus
nTPM: 686.8
2220 Male, age 76, midline 686.8
Pedunculopontine tegmental nucleus
nTPM: 671.2
2334 Male, age 80, both hemispheres 680.7
1921 Female, age 85, both hemispheres 666.8
2338 Male, age 61, both hemispheres 666.1
Periaquaductal grey, anterior
nTPM: 670.2
1947 Male, age 18, unknown 683.4
2502 Female, age 75, unknown 670.5
1795 Male, age 51, unknown 656.7
Periaquaductal grey, dorsal
nTPM: 673.0
1840 Male, age 53, unknown 690.0
2850 Male, age 76, both hemispheres 684.1
2464 Female, age 72, unknown 680.0
1831 Male, age 72, unknown 637.6
Periaquaductal grey, lateral
nTPM: 677.7
2140 Male, age 76, both hemispheres 688.9
2053 Male, age 18, unknown 673.4
2272 Male, age 74, both hemispheres 670.6
Pretectal area
nTPM: 659.1
2273 Male, age 74, both hemispheres 728.3
2224 Female, age 72, unknown 696.0
2667 Female, age 75, unknown 684.8
2825 Male, age 18, unknown 676.0
2316 Male, age 76, right hemisphere 671.3
1944 Female, age 72, unknown 641.7
1817 Female, age 42, unknown 640.9
1815 Male, age 53, unknown 639.8
1816 Male, age 51, unknown 634.1
2407 Male, age 75, both hemispheres 625.5
2007 Male, age 72, unknown 612.1
Red nucleus
nTPM: 663.9
1821 Female, age 72, unknown 712.6
2503 Female, age 72, unknown 693.0
1954 Female, age 42, unknown 688.7
2227 Male, age 72, unknown 679.1
2769 Male, age 72, unknown 679.0
1904 Male, age 53, unknown 677.8
2823 Male, age 76, right hemisphere 673.7
1865 Male, age 51, unknown 667.1
2725 Female, age 75, unknown 661.5
2785 Male, age 18, unknown 631.5
2588 Male, age 74, left hemisphere 613.1
2584 Male, age 75, left hemisphere 589.2
Substantia nigra
nTPM: 672.1
2241 Male, age 72, unknown 724.6
1916 Female, age 42, unknown 716.6
1851 Male, age 51, unknown 706.0
2699 Male, age 18, unknown 700.3
2409 Female, age 72, unknown 667.6
1941 Male, age 53, unknown 665.8
2590 Female, age 75, unknown 657.9
1889 Female, age 72, unknown 655.6
2583 Male, age 75, right hemisphere 613.5
2665 Male, age 74, both hemispheres 613.0
Superior colliculus
nTPM: 650.3
2587 Male, age 74, left hemisphere 677.9
1796 Male, age 53, unknown 669.5
1995 Male, age 72, unknown 664.0
1913 Female, age 42, unknown 653.4
1839 Male, age 51, unknown 653.2
1895 Male, age 76, right hemisphere 651.8
2087 Female, age 72, unknown 643.5
2261 Male, age 18, unknown 635.3
2668 Female, age 75, unknown 631.9
2664 Male, age 75, both hemispheres 622.2
Ventral tegmental area
nTPM: 686.8
1915 Female, age 42, unknown 708.3
2410 Female, age 72, unknown 702.3
2223 Female, age 72, unknown 684.2
1942 Male, age 51, unknown 677.6
2218 Male, age 76, both hemispheres 675.7
2021 Male, age 53, unknown 672.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 708.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 708.1
Samples: 139

Max nTPM: 1522.3
Min nTPM: 355.2
Std nTPM: 190.0
Median nTPM: 664.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1522.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1287.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1191.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1161.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1127.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1125.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1086.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1057.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1050.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1039.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1038.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1026.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1001.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 935.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 933.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 930.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 929.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 923.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 921.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 902.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 890.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 882.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 874.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 872.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 870.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 869.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 868.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 867.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 864.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 860.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 837.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 833.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 826.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 821.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 819.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 790.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 783.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 777.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 766.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 759.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 755.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 755.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 752.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 750.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 749.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 746.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 745.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 743.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 738.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 733.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 729.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 726.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 725.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 713.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 711.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 707.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 703.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 699.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 698.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 692.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 690.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 686.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 684.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 674.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 672.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 672.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 670.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 665.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 664.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 664.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 663.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 655.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 654.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 652.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 651.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 649.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 648.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 646.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 646.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 645.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 643.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 642.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 642.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 636.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 635.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 628.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 626.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 623.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 615.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 613.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 609.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 607.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 606.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 606.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 605.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 605.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 602.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 596.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 596.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 593.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 590.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 590.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 588.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 586.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 585.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 579.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 577.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 577.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 576.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 571.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 567.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 567.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 564.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 562.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 560.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 558.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 548.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 544.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 543.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 539.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 539.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 533.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 531.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 524.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 511.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 508.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 494.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 484.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 477.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 475.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 473.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 473.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 467.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 440.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 437.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 424.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 401.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 381.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 355.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 655.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 655.7
FF:10158-103A5 76 years, female 655.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 83.6
Pig sample Sample description nTPM
Midbrain
nTPM: 74.9
Samples: 4

Max nTPM: 137.7
Min nTPM: 40.0
Sample A Female 137.7
Sample B Female 78.5
Sample C Male 40.0
Sample D Male 43.5
Periaqueductal gray
nTPM: 59.4
Samples: 3

Max nTPM: 65.9
Min nTPM: 52.4
Sample B Female 65.9
Sample C Male 59.8
Sample D Male 52.4
Substantia nigra
nTPM: 83.6
Samples: 4

Max nTPM: 104.1
Min nTPM: 72.0
Sample A Female 104.1
Sample B Female 78.1
Sample C Male 72.0
Sample D Male 80.3
Superior colliculi
nTPM: 66.2
Samples: 4

Max nTPM: 90.2
Min nTPM: 52.0
Sample A Female 90.2
Sample B Female 65.6
Sample C Male 52.0
Sample D Male 56.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 357.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 357.8
Samples: 4

Max nTPM: 372.2
Min nTPM: 332.7
Sample A Male 372.2
Sample B Male 365.7
Sample C Female 332.7
Sample D Female 360.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.4
836 Antisense, RP_Baylor_102943, Mouse strain C57BL/6J (56 days, male) 8.1
837 Antisense, RP_Baylor_102943, Mouse strain C57BL/6J (56 days, male) 2.4
70795736 Antisense, RP_050712_01_H04, Mouse strain C57BL/6J (56 days, male) 0.6

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