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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:516.8 nTPM
HPA:516.8 nTPM
GTEx:725.4 nTPM
FANTOM5:342.6 Scaled Tags Per Million
Pig:703.0 nTPM
Mouse:986.6 nTPM
Allen mouse:8.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 516.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 460.3
1827 Male, age 72, unknown 529.0
2411 Female, age 72, unknown 504.0
1870 Female, age 42, unknown 500.6
2828 Female, age 72, unknown 495.2
2219 Male, age 76, both hemispheres 451.3
1830 Male, age 51, unknown 450.8
1833 Male, age 53, unknown 450.6
2666 Male, age 74, left hemisphere 432.7
2019 Male, age 18, unknown 417.8
2586 Male, age 75, left hemisphere 371.3
Dorsal raphe nucleus
nTPM: 441.8
2750 Male, age 76, both hemispheres 552.5
2298 Female, age 72, unknown 427.6
2047 Male, age 72, unknown 419.2
1828 Male, age 53, unknown 410.8
2016 Female, age 72, unknown 398.9
Inferior colliculus
nTPM: 414.4
2097 Female, age 72, unknown 433.3
1848 Female, age 42, unknown 422.9
1890 Male, age 53, unknown 404.1
2849 Male, age 72, unknown 397.1
Median raphe nucleus
nTPM: 516.8
2220 Male, age 76, midline 516.8
Pedunculopontine tegmental nucleus
nTPM: 468.9
2334 Male, age 80, both hemispheres 482.3
2338 Male, age 61, both hemispheres 466.9
1921 Female, age 85, both hemispheres 457.5
Periaquaductal grey, anterior
nTPM: 469.9
1795 Male, age 51, unknown 487.6
1947 Male, age 18, unknown 485.1
2502 Female, age 75, unknown 437.0
Periaquaductal grey, dorsal
nTPM: 418.0
1831 Male, age 72, unknown 454.1
2850 Male, age 76, both hemispheres 409.7
2464 Female, age 72, unknown 406.8
1840 Male, age 53, unknown 401.4
Periaquaductal grey, lateral
nTPM: 440.9
2053 Male, age 18, unknown 482.1
2272 Male, age 74, both hemispheres 448.0
2140 Male, age 76, both hemispheres 392.8
Pretectal area
nTPM: 470.4
1816 Male, age 51, unknown 529.1
1944 Female, age 72, unknown 514.3
1815 Male, age 53, unknown 497.8
2667 Female, age 75, unknown 469.5
2407 Male, age 75, both hemispheres 459.8
2273 Male, age 74, both hemispheres 458.2
1817 Female, age 42, unknown 458.1
2825 Male, age 18, unknown 457.0
2007 Male, age 72, unknown 449.0
2224 Female, age 72, unknown 447.4
2316 Male, age 76, right hemisphere 434.2
Red nucleus
nTPM: 461.1
2823 Male, age 76, right hemisphere 490.0
2725 Female, age 75, unknown 478.0
2584 Male, age 75, left hemisphere 475.7
1821 Female, age 72, unknown 469.4
2503 Female, age 72, unknown 468.5
1954 Female, age 42, unknown 467.0
1904 Male, age 53, unknown 466.1
1865 Male, age 51, unknown 460.8
2588 Male, age 74, left hemisphere 459.4
2769 Male, age 72, unknown 437.8
2227 Male, age 72, unknown 437.3
2785 Male, age 18, unknown 423.6
Substantia nigra
nTPM: 452.2
1889 Female, age 72, unknown 477.0
1916 Female, age 42, unknown 477.0
2241 Male, age 72, unknown 470.2
1851 Male, age 51, unknown 463.2
1941 Male, age 53, unknown 457.9
2590 Female, age 75, unknown 456.7
2409 Female, age 72, unknown 453.2
2583 Male, age 75, right hemisphere 448.4
2699 Male, age 18, unknown 435.6
2665 Male, age 74, both hemispheres 383.0
Superior colliculus
nTPM: 467.5
1913 Female, age 42, unknown 516.9
2261 Male, age 18, unknown 514.7
2587 Male, age 74, left hemisphere 510.7
1796 Male, age 53, unknown 502.4
2087 Female, age 72, unknown 496.5
2668 Female, age 75, unknown 466.8
1995 Male, age 72, unknown 441.2
1895 Male, age 76, right hemisphere 431.7
1839 Male, age 51, unknown 415.4
2664 Male, age 75, both hemispheres 378.4
Ventral tegmental area
nTPM: 482.2
2223 Female, age 72, unknown 510.9
2218 Male, age 76, both hemispheres 499.3
2410 Female, age 72, unknown 488.7
1915 Female, age 42, unknown 472.8
2021 Male, age 53, unknown 469.3
1942 Male, age 51, unknown 452.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 725.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 725.4
Samples: 139

Max nTPM: 1544.9
Min nTPM: 205.9
Std nTPM: 264.3
Median nTPM: 707.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1544.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1470.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1413.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1390.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1388.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1345.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1278.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1272.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1234.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1184.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1177.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1177.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1131.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1120.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1109.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1099.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1045.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1045.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 968.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 968.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 963.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 941.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 935.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 923.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 914.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 903.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 900.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 888.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 875.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 854.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 842.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 840.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 838.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 836.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 833.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 827.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 823.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 822.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 820.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 817.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 811.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 811.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 810.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 806.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 802.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 796.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 795.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 791.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 784.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 775.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 769.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 758.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 758.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 756.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 755.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 752.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 746.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 746.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 745.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 743.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 740.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 732.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 731.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 728.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 727.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 718.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 717.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 715.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 710.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 707.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 706.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 705.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 683.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 682.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 674.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 673.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 669.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 669.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 669.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 662.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 655.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 653.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 638.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 638.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 631.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 624.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 624.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 616.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 616.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 615.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 613.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 609.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 608.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 605.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 601.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 596.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 589.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 581.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 574.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 573.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 573.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 571.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 563.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 558.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 555.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 554.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 552.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 550.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 539.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 527.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 524.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 522.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 517.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 502.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 499.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 489.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 488.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 488.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 481.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 477.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 445.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 433.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 432.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 421.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 408.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 407.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 401.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 380.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 351.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 335.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 330.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 327.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 326.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 325.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 318.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 315.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 283.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 255.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 205.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 342.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 342.6
FF:10158-103A5 76 years, female 342.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 703.0
Pig sample Sample description nTPM
Midbrain
nTPM: 703.1
Samples: 4

Max nTPM: 1121.4
Min nTPM: 454.0
Sample A Female 1121.4
Sample B Female 639.2
Sample C Male 597.6
Sample D Male 454.0
Periaqueductal gray
nTPM: 458.2
Samples: 3

Max nTPM: 507.0
Min nTPM: 429.2
Sample B Female 507.0
Sample C Male 438.5
Sample D Male 429.2
Substantia nigra
nTPM: 584.5
Samples: 4

Max nTPM: 716.8
Min nTPM: 424.0
Sample A Female 716.8
Sample B Female 424.0
Sample C Male 588.1
Sample D Male 609.2
Superior colliculi
nTPM: 497.5
Samples: 4

Max nTPM: 591.3
Min nTPM: 324.9
Sample A Female 591.3
Sample B Female 324.9
Sample C Male 523.5
Sample D Male 550.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 986.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 986.6
Samples: 4

Max nTPM: 1014.7
Min nTPM: 945.2
Sample A Male 999.4
Sample B Male 945.2
Sample C Female 987.1
Sample D Female 1014.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.7
71016595 Antisense, RP_050725_03_A05, Mouse strain C57BL/6J (56 days, male) 9.9
68632984 Antisense, RP_050125_02_B12, Mouse strain C57BL/6J (56 days, male) 7.5

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