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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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38.164
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:174.9 nTPM
HPA:174.9 nTPM
FANTOM5:519.2 Scaled Tags Per Million
Mouse:9.8 nTPM
Allen mouse:5.8 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA000798
Pons mean intensity 38.164
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 6.273
Parabrachial nucleus 22.685
Principle sensory trigeminal nucleus 10.992
Locus coeruleus 38.164
Pontine nucleus 3.793
Vestibular nucleus 35.673
Pontine reticular nucleus, oral 5.078
Lateral lemniscus 3.763
Superior paraolivary nucleus 17.901

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 174.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 140.3
2188 Female, age 91, both hemispheres 162.0
2301 Female, age 85, both hemispheres 161.7
2090 Male, age 80, both hemispheres 154.6
1984 Male, age 76, both hemispheres 83.0
Area postrema
nTPM: 101.9
2306 Male, age 80, both hemispheres 153.9
2799 Male, age 61, both hemispheres 86.3
2054 Male, age 76, both hemispheres 65.5
Cuneate nuclei
nTPM: 113.9
2381 Male, age 80, both hemispheres 129.6
2376 Male, age 61, both hemispheres 108.4
2131 Male, age 76, both hemispheres 103.8
Dorsal cochlear nucleus
nTPM: 99.8
2187 Female, age 91, both hemispheres 131.4
2378 Male, age 80, both hemispheres 110.7
2058 Male, age 76, both hemispheres 91.8
2802 Male, age 74, right hemisphere 82.8
2370 Male, age 61, both hemispheres 82.0
Dorsal medullary reticular nucleus
nTPM: 105.6
2040 Female, age 85, both hemispheres 117.5
2373 Male, age 61, both hemispheres 102.1
2088 Male, age 76, both hemispheres 97.2
Dorsal motor vagal complex
nTPM: 78.8
2185 Male, age 76, both hemispheres 105.6
2000 Male, age 74, unknown 96.5
2133 Female, age 91, both hemispheres 81.6
2807 Female, age 85, both hemispheres 77.4
2813 Female, age 72, unknown 75.1
2643 Male, age 74, both hemispheres 69.3
2844 Male, age 55, unknown 67.1
2797 Male, age 61, both hemispheres 57.6
Dorsal tegmental nucleus
nTPM: 97.2
2083 Male, age 80, both hemispheres 131.6
2326 Male, age 74, both hemispheres 105.5
1936 Male, age 76, left hemisphere 86.8
2358 Male, age 61, both hemispheres 65.0
Dorsolateral tegmental area
nTPM: 107.6
2751 Female, age 85, both hemispheres 147.8
2654 Male, age 80, both hemispheres 120.6
2337 Male, age 61, both hemispheres 113.2
2360 Male, age 74, both hemispheres 88.7
2141 Male, age 76, both hemispheres 67.7
Gigantocellular reticular nuclei, medullary
nTPM: 119.4
2314 Male, age 61, both hemispheres 192.8
1876 Female, age 85, both hemispheres 133.4
2387 Female, age 91, both hemispheres 122.4
2310 Male, age 80, both hemispheres 105.1
2022 Male, age 76, right hemisphere 81.9
2462 Male, age 74, both hemispheres 80.9
Gigantocellular reticular nuclei, pars
nTPM: 108.1
2336 Male, age 61, both hemispheres 124.6
2330 Male, age 80, both hemispheres 113.8
2706 Male, age 80, both hemispheres 107.1
2084 Female, age 85, both hemispheres 103.2
2168 Male, age 76, both hemispheres 91.7
Inferior olive
nTPM: 145.9
2178 Male, age 61, both hemispheres 188.0
2085 Female, age 85, both hemispheres 150.3
2563 Male, age 74, both hemispheres 144.1
2628 Female, age 91, both hemispheres 127.6
2379 Male, age 80, both hemispheres 119.3
Kolliker-Fuse nucleus
nTPM: 118.1
2793 Female, age 91, left hemisphere 157.0
2163 Male, age 80, both hemispheres 100.6
2315 Male, age 76, right hemisphere 96.8
Lateral lemniscal nuclei
nTPM: 109.7
2320 Female, age 91, left hemisphere 139.9
2746 Female, age 85, left hemisphere 125.6
2169 Male, age 76, both hemispheres 104.9
2036 Male, age 80, both hemispheres 89.3
2453 Male, age 74, right hemisphere 88.6
Lateral medullary reticular nucleus
nTPM: 146.1
2305 Male, age 74, both hemispheres 179.4
2852 Male, age 80, both hemispheres 173.0
2374 Male, age 61, both hemispheres 160.2
2190 Female, age 85, both hemispheres 143.4
2804 Female, age 91, both hemispheres 114.1
2044 Male, age 76, both hemispheres 106.5
Lateral parabrachial nucleus
nTPM: 122.2
2792 Male, age 76, both hemispheres 175.1
2013 Male, age 80, both hemispheres 129.4
2139 Female, age 85, right hemisphere 109.6
2790 Male, age 61, both hemispheres 74.5
Lateral vestibular nucleus
nTPM: 105.9
2311 Male, age 80, both hemispheres 122.4
2184 Male, age 76, both hemispheres 89.5
Locus coeruleus
nTPM: 68.8
2317 Female, age 72, unknown 81.1
2162 Male, age 80, both hemispheres 78.4
2720 Male, age 74, both hemispheres 72.2
2123 Female, age 91, both hemispheres 70.8
2788 Male, age 74, unknown 63.6
2014 Male, age 55, unknown 61.2
1980 Male, age 76, both hemispheres 54.6
Medial olivary nucleus
nTPM: 174.9
1943 Male, age 61, both hemispheres 218.5
1962 Male, age 76, both hemispheres 190.0
2138 Female, age 91, both hemispheres 157.7
2851 Male, age 80, both hemispheres 133.6
Medial parabrachial nucleus
nTPM: 110.2
2170 Female, age 91, both hemispheres 140.2
2463 Female, age 85, right hemisphere 126.7
2854 Male, age 80, both hemispheres 111.5
2786 Male, age 76, both hemispheres 101.5
2156 Male, age 61, both hemispheres 71.3
Medial periolivary nuclei
nTPM: 111.9
2081 Male, age 80, both hemispheres 137.8
2791 Male, age 74, right hemisphere 133.4
2458 Female, age 91, both hemispheres 110.2
2063 Male, age 76, both hemispheres 104.9
2171 Female, age 85, both hemispheres 73.5
Medial vestibular nucleus
nTPM: 105.2
2801 Male, age 74, both hemispheres 127.6
2093 Male, age 80, both hemispheres 116.3
2803 Female, age 91, both hemispheres 115.4
2743 Female, age 85, both hemispheres 104.4
2624 Male, age 61, both hemispheres 103.7
2134 Male, age 76, both hemispheres 63.8
Motor facial nucleus
nTPM: 112.4
2126 Male, age 61, both hemispheres 144.0
2365 Male, age 74, right hemisphere 131.3
2697 Female, age 85, both hemispheres 127.4
2062 Male, age 76, both hemispheres 93.2
2327 Male, age 80, both hemispheres 92.2
2795 Female, age 91, both hemispheres 86.5
Motor hypoglossal nucleus
nTPM: 104.8
2182 Male, age 80, both hemispheres 132.4
2125 Female, age 91, both hemispheres 130.4
2132 Female, age 85, both hemispheres 125.6
2461 Male, age 61, both hemispheres 80.3
2277 Male, age 76, both hemispheres 55.3
Motor trigeminal nucleus
nTPM: 109.2
2321 Female, age 91, both hemispheres 126.0
2560 Male, age 74, both hemispheres 117.9
2079 Male, age 80, both hemispheres 107.4
2309 Male, age 76, both hemispheres 104.4
2335 Male, age 61, both hemispheres 90.4
Nuclei of the trapezoid body
nTPM: 101.0
2166 Male, age 80, both hemispheres 121.1
2159 Male, age 61, both hemispheres 108.1
1983 Male, age 76, both hemispheres 104.6
2368 Female, age 91, both hemispheres 102.1
2735 Female, age 85, both hemispheres 69.0
Nucleus ambiguus
nTPM: 154.3
2071 Male, age 76, both hemispheres 195.6
2096 Female, age 85, both hemispheres 113.1
Nucleus cuneatus
nTPM: 111.8
2380 Male, age 80, both hemispheres 146.1
2808 Female, age 85, both hemispheres 145.2
2100 Male, age 76, both hemispheres 121.9
2564 Male, age 74, both hemispheres 103.0
2562 Male, age 61, both hemispheres 79.4
2805 Female, age 91, both hemispheres 75.2
Nucleus gracilis
nTPM: 136.7
2382 Male, age 80, both hemispheres 159.7
2627 Male, age 74, both hemispheres 128.1
2299 Female, age 85, both hemispheres 122.4
Nucleus raphe magnus
nTPM: 96.7
2328 Male, age 80, both hemispheres 117.5
2051 Male, age 76, both hemispheres 114.0
2459 Female, age 91, both hemispheres 110.7
2455 Male, age 74, both hemispheres 103.9
2160 Male, age 61, both hemispheres 76.8
2172 Female, age 85, both hemispheres 57.4
Nucleus raphe obscurus
nTPM: 170.1
2845 Female, age 85, midline 190.4
2142 Male, age 76, midline 174.1
2800 Male, age 61, midline 145.9
Nucleus raphe pallidus
nTPM: 163.5
2145 Male, age 76, midline 203.8
1924 Male, age 61, midline 163.4
2183 Male, age 80, midline 123.1
Nucleus tractus solitarii
nTPM: 68.3
2191 Female, age 85, both hemispheres 75.8
2307 Male, age 80, both hemispheres 73.1
2144 Female, age 91, right hemisphere 63.2
2656 Male, age 76, both hemispheres 61.0
Paramedian reticular nucleus
nTPM: 104.2
2057 Male, age 80, both hemispheres 122.0
2052 Male, age 76, both hemispheres 104.5
2050 Female, age 85, both hemispheres 100.1
2313 Male, age 61, both hemispheres 90.1
Parvicellular reticular nuclei
nTPM: 107.8
2119 Male, age 80, both hemispheres 126.9
2095 Male, age 76, both hemispheres 121.0
2558 Male, age 74, both hemispheres 75.4
Parvicellular reticular nuclei, medullary
nTPM: 102.6
2189 Female, age 91, both hemispheres 114.5
2181 Male, age 80, left hemisphere 97.7
2091 Female, age 85, both hemispheres 95.8
Peritrigeminal nucleus
nTPM: 126.1
2067 Female, age 85, both hemispheres 134.9
2179 Male, age 61, both hemispheres 124.5
2136 Male, age 76, both hemispheres 118.9
Pontine nuclei
nTPM: 125.2
2454 Male, age 74, left hemisphere 177.8
2319 Female, age 91, both hemispheres 152.4
2109 Female, age 72, unknown 139.7
2115 Male, age 80, left hemisphere 125.7
1968 Male, age 76, left hemisphere 120.8
2727 Male, age 61, right hemisphere 101.9
1863 Male, age 55, unknown 99.0
2787 Female, age 85, both hemispheres 83.9
Pontine raphe nucleus
nTPM: 84.0
2122 Female, age 85, midline 88.7
2853 Male, age 76, midline 79.3
Posteroventral cochlear nucleus
nTPM: 130.3
2135 Female, age 91, both hemispheres 190.5
2341 Male, age 80, both hemispheres 146.1
2070 Male, age 76, both hemispheres 134.8
2752 Female, age 85, both hemispheres 91.9
2371 Male, age 61, both hemispheres 88.4
Prepositus hypoglossal nucleus
nTPM: 112.5
2855 Female, age 85, right hemisphere 133.0
2086 Male, age 80, both hemispheres 92.0
Principal sensory trigeminal nucleus
nTPM: 101.7
2367 Female, age 91, left hemisphere 143.3
2008 Male, age 80, left hemisphere 92.4
2324 Male, age 76, both hemispheres 89.4
2158 Male, age 61, both hemispheres 81.9
Reticular pontine nucleus, caudal
nTPM: 123.9
2559 Male, age 74, both hemispheres 140.6
2092 Male, age 76, both hemispheres 138.0
2457 Female, age 91, both hemispheres 127.9
2332 Male, age 80, right hemisphere 88.9
Reticular pontine nucleus, oral
nTPM: 133.8
2366 Female, age 91, both hemispheres 161.1
2361 Male, age 74, both hemispheres 159.5
1939 Male, age 80, both hemispheres 119.0
2012 Female, age 85, both hemispheres 116.6
2167 Male, age 76, both hemispheres 112.9
Reticulotegmental nucleus
nTPM: 92.6
2322 Female, age 91, both hemispheres 111.3
2333 Male, age 80, both hemispheres 103.2
2452 Male, age 74, both hemispheres 90.7
2325 Male, age 76, both hemispheres 65.2
Spinal trigeminal nucleus, caudal
nTPM: 122.5
2312 Male, age 61, both hemispheres 173.0
2308 Male, age 80, both hemispheres 133.0
2447 Male, age 76, both hemispheres 112.5
2390 Female, age 91, both hemispheres 102.2
2642 Male, age 74, both hemispheres 91.9
Spinal trigeminal nucleus, interpolar
nTPM: 92.3
2033 Male, age 80, both hemispheres 103.1
2386 Female, age 85, both hemispheres 101.0
2389 Female, age 91, both hemispheres 97.5
2066 Male, age 76, right hemisphere 86.8
2625 Male, age 61, both hemispheres 72.9
Spinal trigeminal nucleus, oral
nTPM: 97.9
1978 Male, age 76, both hemispheres 108.6
2164 Male, age 80, both hemispheres 101.8
2737 Female, age 85, both hemispheres 83.2
Spinal vestibular nucleus
nTPM: 109.5
2748 Male, age 76, both hemispheres 143.5
2186 Female, age 91, both hemispheres 118.7
2806 Female, age 85, both hemispheres 117.0
2780 Male, age 80, both hemispheres 105.9
2384 Male, age 74, both hemispheres 91.5
2796 Male, age 61, both hemispheres 80.1
Subcoeruleus area
nTPM: 105.0
2369 Female, age 85, left hemisphere 159.8
2089 Male, age 76, left hemisphere 112.3
1958 Male, age 80, both hemispheres 100.3
2323 Female, age 91, left hemisphere 82.8
2451 Male, age 74, both hemispheres 70.1
Superior olive
nTPM: 121.7
2020 Male, age 76, both hemispheres 146.9
2364 Male, age 74, right hemisphere 142.3
2329 Male, age 80, right hemisphere 120.2
2561 Female, age 91, both hemispheres 102.0
1875 Female, age 85, both hemispheres 97.1
Superior vestibular nucleus
nTPM: 106.0
2015 Male, age 80, both hemispheres 111.2
2383 Male, age 74, both hemispheres 104.5
2061 Male, age 76, both hemispheres 102.5
Ventral medullary reticular nucleus
nTPM: 130.1
2372 Male, age 61, both hemispheres 132.4
2060 Male, age 76, both hemispheres 127.7
Ventral periolivary nuclei
nTPM: 105.4
2023 Male, age 76, both hemispheres 150.6
2165 Male, age 80, both hemispheres 102.7
2130 Female, age 85, both hemispheres 86.1
2794 Female, age 91, left hemisphere 82.1
Ventrolateral medulla, A1-C1 cell groups
nTPM: 127.9
2180 Male, age 61, both hemispheres 157.7
2118 Male, age 80, both hemispheres 150.5
2741 Female, age 85, both hemispheres 114.3
2302 Female, age 91, both hemispheres 109.1
1986 Male, age 76, both hemispheres 107.9
Ventrolateral tegmental area, A5 NE cell group
nTPM: 115.7
1959 Male, age 76, both hemispheres 124.4
2359 Male, age 61, both hemispheres 119.7
2456 Female, age 91, both hemispheres 115.9
2840 Female, age 85, both hemispheres 115.0
2161 Male, age 80, both hemispheres 111.3
2449 Male, age 74, both hemispheres 108.0

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 519.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 436.0
FF:10165-103B3 76 years, female 503.0
FF:10182-103D2 60 years, female 368.9
Medulla oblongata
Scaled Tags Per Million: 519.2
FF:10155-103A2 76 years, female 542.9
FF:10174-103C3 60 years, female 517.2
FF:10038-101F2 18-64 years, mixed 497.4
Pons
Scaled Tags Per Million: 371.8
FF:10033-101E6 18-54 years, mixed 371.8

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 9.8
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 9.8
Samples: 4

Max nTPM: 11.3
Min nTPM: 8.8
Sample A Male 10.2
Sample B Male 9.0
Sample C Female 11.3
Sample D Female 8.8

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 5.8
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 5.4
532642 Antisense, RP_040810_02_H07, Mouse strain C57BL/6J (56 days, male) 5.4
Pons
Expression energy: 5.8
532642 Antisense, RP_040810_02_H07, Mouse strain C57BL/6J (56 days, male) 5.8

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