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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:179.0 nTPM
HPA:179.0 nTPM
GTEx:140.9 nTPM
FANTOM5:164.9 Scaled Tags Per Million
Pig:58.6 nTPM
Mouse:66.5 nTPM
Allen mouse:9.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 179.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 174.4
2586 Male, age 75, left hemisphere 194.8
2019 Male, age 18, unknown 183.0
2828 Female, age 72, unknown 181.4
1833 Male, age 53, unknown 177.9
1830 Male, age 51, unknown 173.3
2666 Male, age 74, left hemisphere 172.2
2411 Female, age 72, unknown 172.0
1827 Male, age 72, unknown 169.6
1870 Female, age 42, unknown 165.3
2219 Male, age 76, both hemispheres 154.8
Dorsal raphe nucleus
nTPM: 165.9
2750 Male, age 76, both hemispheres 182.0
2047 Male, age 72, unknown 173.6
1828 Male, age 53, unknown 168.7
2016 Female, age 72, unknown 165.6
2298 Female, age 72, unknown 139.5
Inferior colliculus
nTPM: 167.8
2849 Male, age 72, unknown 177.8
1848 Female, age 42, unknown 174.1
1890 Male, age 53, unknown 170.4
2097 Female, age 72, unknown 148.8
Median raphe nucleus
nTPM: 178.6
2220 Male, age 76, midline 178.6
Pedunculopontine tegmental nucleus
nTPM: 165.1
2334 Male, age 80, both hemispheres 168.5
2338 Male, age 61, both hemispheres 166.3
1921 Female, age 85, both hemispheres 160.6
Periaquaductal grey, anterior
nTPM: 150.8
1947 Male, age 18, unknown 156.9
1795 Male, age 51, unknown 155.9
2502 Female, age 75, unknown 139.8
Periaquaductal grey, dorsal
nTPM: 165.6
2850 Male, age 76, both hemispheres 177.8
2464 Female, age 72, unknown 174.3
1831 Male, age 72, unknown 155.5
1840 Male, age 53, unknown 154.7
Periaquaductal grey, lateral
nTPM: 163.8
2140 Male, age 76, both hemispheres 189.6
2053 Male, age 18, unknown 156.7
2272 Male, age 74, both hemispheres 145.1
Pretectal area
nTPM: 164.8
2316 Male, age 76, right hemisphere 181.4
1817 Female, age 42, unknown 172.4
1815 Male, age 53, unknown 172.0
2007 Male, age 72, unknown 171.9
1944 Female, age 72, unknown 169.2
2667 Female, age 75, unknown 167.4
2407 Male, age 75, both hemispheres 160.5
2825 Male, age 18, unknown 159.5
1816 Male, age 51, unknown 159.1
2224 Female, age 72, unknown 150.5
2273 Male, age 74, both hemispheres 148.6
Red nucleus
nTPM: 179.0
2588 Male, age 74, left hemisphere 210.0
2823 Male, age 76, right hemisphere 191.5
2503 Female, age 72, unknown 186.4
2725 Female, age 75, unknown 182.6
2785 Male, age 18, unknown 179.8
1865 Male, age 51, unknown 179.0
2769 Male, age 72, unknown 176.6
2227 Male, age 72, unknown 174.4
1954 Female, age 42, unknown 172.9
1904 Male, age 53, unknown 172.6
1821 Female, age 72, unknown 170.0
2584 Male, age 75, left hemisphere 152.0
Substantia nigra
nTPM: 170.1
2583 Male, age 75, right hemisphere 178.3
1916 Female, age 42, unknown 176.9
1941 Male, age 53, unknown 172.2
2699 Male, age 18, unknown 172.0
1889 Female, age 72, unknown 169.8
2241 Male, age 72, unknown 169.6
2409 Female, age 72, unknown 169.3
1851 Male, age 51, unknown 168.5
2590 Female, age 75, unknown 165.0
2665 Male, age 74, both hemispheres 159.4
Superior colliculus
nTPM: 162.0
2668 Female, age 75, unknown 173.2
1895 Male, age 76, right hemisphere 168.8
1839 Male, age 51, unknown 165.7
1796 Male, age 53, unknown 165.0
2087 Female, age 72, unknown 164.3
1913 Female, age 42, unknown 162.9
1995 Male, age 72, unknown 156.3
2664 Male, age 75, both hemispheres 155.0
2261 Male, age 18, unknown 154.9
2587 Male, age 74, left hemisphere 154.2
Ventral tegmental area
nTPM: 167.1
2218 Male, age 76, both hemispheres 177.3
2410 Female, age 72, unknown 173.2
1915 Female, age 42, unknown 164.9
1942 Male, age 51, unknown 164.2
2223 Female, age 72, unknown 162.8
2021 Male, age 53, unknown 160.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 140.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 140.9
Samples: 139

Max nTPM: 260.6
Min nTPM: 87.3
Std nTPM: 33.0
Median nTPM: 138.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 260.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 240.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 231.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 225.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 216.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 199.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 199.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 198.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 194.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 192.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 190.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 189.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 186.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 185.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 185.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 182.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 182.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 181.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 181.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 179.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 178.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 177.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 175.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 175.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 164.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 162.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 161.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 161.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 159.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 158.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 158.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 158.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 158.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 158.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 158.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 156.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 156.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 155.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 155.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 155.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 153.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 153.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 153.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 152.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 151.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 150.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 150.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 150.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 149.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 149.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 148.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 148.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 147.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 147.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 147.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 147.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 146.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 145.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 144.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 143.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 143.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 143.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 143.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 142.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 142.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 142.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 142.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 141.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 140.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 138.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 136.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 135.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 134.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 134.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 133.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 133.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 133.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 133.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 133.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 132.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 131.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 131.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 131.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 129.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 127.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 127.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 126.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 126.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 125.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 125.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 125.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 125.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 123.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 122.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 122.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 122.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 121.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 121.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 120.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 119.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 119.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 119.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 118.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 118.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 114.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 114.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 113.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 112.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 111.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 110.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 109.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 108.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 108.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 108.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 108.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 108.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 107.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 107.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 105.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 105.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 104.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 103.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 103.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 98.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 98.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 98.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 98.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 98.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 98.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 98.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 97.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 97.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 97.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 96.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 96.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 95.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 89.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 88.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 87.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 164.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 164.9
FF:10158-103A5 76 years, female 164.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 58.6
Pig sample Sample description nTPM
Midbrain
nTPM: 58.6
Samples: 4

Max nTPM: 68.8
Min nTPM: 50.1
Sample A Female 61.5
Sample B Female 50.1
Sample C Male 68.8
Sample D Male 53.9
Periaqueductal gray
nTPM: 52.8
Samples: 3

Max nTPM: 56.0
Min nTPM: 50.5
Sample B Female 56.0
Sample C Male 50.5
Sample D Male 51.8
Substantia nigra
nTPM: 56.2
Samples: 4

Max nTPM: 66.1
Min nTPM: 46.3
Sample A Female 46.3
Sample B Female 54.4
Sample C Male 57.9
Sample D Male 66.1
Superior colliculi
nTPM: 54.2
Samples: 4

Max nTPM: 66.5
Min nTPM: 43.5
Sample A Female 43.5
Sample B Female 49.0
Sample C Male 66.5
Sample D Male 57.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 66.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 66.5
Samples: 4

Max nTPM: 75.3
Min nTPM: 54.0
Sample A Male 54.0
Sample B Male 75.3
Sample C Female 64.0
Sample D Female 72.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 9.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.9
69736400 Antisense, RP_050503_04_G01, Mouse strain C57BL/6J (56 days, male) 9.9

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