We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
APOE
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • METABOLIC
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • METABOLIC

  • APOE
BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:1106.9 nTPM
HPA:1106.9 nTPM
FANTOM5:1275.3 Scaled Tags Per Million
Pig:441.6 nTPM
Allen mouse:20.1 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 1106.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 542.7
2301 Female, age 85, both hemispheres 572.0
2090 Male, age 80, both hemispheres 564.9
1984 Male, age 76, both hemispheres 543.6
2188 Female, age 91, both hemispheres 490.2
Dorsal cochlear nucleus
nTPM: 570.3
2370 Male, age 61, both hemispheres 780.9
2058 Male, age 76, both hemispheres 570.5
2187 Female, age 91, both hemispheres 537.6
2378 Male, age 80, both hemispheres 494.8
2802 Male, age 74, right hemisphere 467.4
Dorsal tegmental nucleus
nTPM: 820.4
2358 Male, age 61, both hemispheres 994.6
1936 Male, age 76, left hemisphere 861.5
2083 Male, age 80, both hemispheres 783.1
2326 Male, age 74, both hemispheres 642.5
Dorsolateral tegmental area
nTPM: 1106.9
2337 Male, age 61, both hemispheres 2535.6
2141 Male, age 76, both hemispheres 813.1
2654 Male, age 80, both hemispheres 799.1
2751 Female, age 85, both hemispheres 740.0
2360 Male, age 74, both hemispheres 646.8
Kolliker-Fuse nucleus
nTPM: 663.4
2315 Male, age 76, right hemisphere 800.1
2163 Male, age 80, both hemispheres 748.1
2793 Female, age 91, left hemisphere 442.1
Lateral lemniscal nuclei
nTPM: 517.5
2746 Female, age 85, left hemisphere 892.5
2169 Male, age 76, both hemispheres 472.0
2453 Male, age 74, right hemisphere 457.1
2320 Female, age 91, left hemisphere 427.8
2036 Male, age 80, both hemispheres 337.9
Lateral parabrachial nucleus
nTPM: 702.1
2139 Female, age 85, right hemisphere 818.4
2013 Male, age 80, both hemispheres 793.7
2792 Male, age 76, both hemispheres 663.9
2790 Male, age 61, both hemispheres 532.4
Lateral vestibular nucleus
nTPM: 726.8
2184 Male, age 76, both hemispheres 773.9
2311 Male, age 80, both hemispheres 679.6
Locus coeruleus
nTPM: 829.3
2317 Female, age 72, unknown 1067.5
1980 Male, age 76, both hemispheres 982.0
2014 Male, age 55, unknown 978.9
2123 Female, age 91, both hemispheres 808.0
2162 Male, age 80, both hemispheres 691.5
2720 Male, age 74, both hemispheres 667.5
2788 Male, age 74, unknown 609.9
Medial olivary nucleus
nTPM: 768.0
1943 Male, age 61, both hemispheres 954.8
1962 Male, age 76, both hemispheres 794.7
2851 Male, age 80, both hemispheres 740.8
2138 Female, age 91, both hemispheres 581.6
Medial parabrachial nucleus
nTPM: 735.3
2786 Male, age 76, both hemispheres 817.4
2463 Female, age 85, right hemisphere 796.1
2156 Male, age 61, both hemispheres 767.4
2170 Female, age 91, both hemispheres 678.1
2854 Male, age 80, both hemispheres 617.6
Medial periolivary nuclei
nTPM: 549.8
2081 Male, age 80, both hemispheres 865.8
2063 Male, age 76, both hemispheres 525.1
2791 Male, age 74, right hemisphere 470.8
2171 Female, age 85, both hemispheres 469.9
2458 Female, age 91, both hemispheres 417.4
Motor facial nucleus
nTPM: 492.0
2126 Male, age 61, both hemispheres 647.2
2062 Male, age 76, both hemispheres 585.2
2365 Male, age 74, right hemisphere 498.9
2697 Female, age 85, both hemispheres 433.6
2795 Female, age 91, both hemispheres 414.7
2327 Male, age 80, both hemispheres 372.5
Motor trigeminal nucleus
nTPM: 662.7
2335 Male, age 61, both hemispheres 963.8
2309 Male, age 76, both hemispheres 757.6
2079 Male, age 80, both hemispheres 662.5
2560 Male, age 74, both hemispheres 481.8
2321 Female, age 91, both hemispheres 447.6
Nuclei of the trapezoid body
nTPM: 512.5
1983 Male, age 76, both hemispheres 635.5
2159 Male, age 61, both hemispheres 555.5
2166 Male, age 80, both hemispheres 514.2
2735 Female, age 85, both hemispheres 467.1
2368 Female, age 91, both hemispheres 390.2
Paramedian reticular nucleus
nTPM: 573.8
2313 Male, age 61, both hemispheres 764.2
2057 Male, age 80, both hemispheres 562.2
2052 Male, age 76, both hemispheres 502.3
2050 Female, age 85, both hemispheres 466.5
Pontine nuclei
nTPM: 558.3
2115 Male, age 80, left hemisphere 1027.0
1968 Male, age 76, left hemisphere 634.8
2787 Female, age 85, both hemispheres 571.6
2319 Female, age 91, both hemispheres 511.8
1863 Male, age 55, unknown 487.4
2727 Male, age 61, right hemisphere 467.8
2109 Female, age 72, unknown 432.8
2454 Male, age 74, left hemisphere 332.8
Pontine raphe nucleus
nTPM: 727.9
2853 Male, age 76, midline 911.0
2122 Female, age 85, midline 544.9
Posteroventral cochlear nucleus
nTPM: 646.5
2371 Male, age 61, both hemispheres 808.3
2070 Male, age 76, both hemispheres 695.6
2752 Female, age 85, both hemispheres 640.4
2341 Male, age 80, both hemispheres 552.1
2135 Female, age 91, both hemispheres 536.1
Principal sensory trigeminal nucleus
nTPM: 568.7
2324 Male, age 76, both hemispheres 886.2
2008 Male, age 80, left hemisphere 479.1
2367 Female, age 91, left hemisphere 468.7
2158 Male, age 61, both hemispheres 440.7
Reticular pontine nucleus, caudal
nTPM: 498.8
2092 Male, age 76, both hemispheres 577.2
2559 Male, age 74, both hemispheres 505.8
2332 Male, age 80, right hemisphere 499.8
2457 Female, age 91, both hemispheres 412.1
Reticular pontine nucleus, oral
nTPM: 609.8
1939 Male, age 80, both hemispheres 841.1
2167 Male, age 76, both hemispheres 829.0
2012 Female, age 85, both hemispheres 606.6
2366 Female, age 91, both hemispheres 404.9
2361 Male, age 74, both hemispheres 367.2
Reticulotegmental nucleus
nTPM: 654.1
2325 Male, age 76, both hemispheres 752.0
2333 Male, age 80, both hemispheres 737.1
2452 Male, age 74, both hemispheres 606.7
2322 Female, age 91, both hemispheres 520.5
Spinal trigeminal nucleus, oral
nTPM: 651.5
1978 Male, age 76, both hemispheres 701.6
2737 Female, age 85, both hemispheres 651.4
2164 Male, age 80, both hemispheres 601.4
Subcoeruleus area
nTPM: 700.9
2451 Male, age 74, both hemispheres 819.4
2323 Female, age 91, left hemisphere 770.6
2369 Female, age 85, left hemisphere 716.9
1958 Male, age 80, both hemispheres 658.3
2089 Male, age 76, left hemisphere 539.2
Superior olive
nTPM: 485.0
2020 Male, age 76, both hemispheres 542.3
2561 Female, age 91, both hemispheres 509.2
2364 Male, age 74, right hemisphere 496.3
2329 Male, age 80, right hemisphere 477.8
1875 Female, age 85, both hemispheres 399.5
Superior vestibular nucleus
nTPM: 626.3
2061 Male, age 76, both hemispheres 719.3
2015 Male, age 80, both hemispheres 646.5
2383 Male, age 74, both hemispheres 513.0
Ventral periolivary nuclei
nTPM: 466.1
2023 Male, age 76, both hemispheres 502.4
2165 Male, age 80, both hemispheres 492.2
2794 Female, age 91, left hemisphere 445.9
2130 Female, age 85, both hemispheres 424.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 610.5
2359 Male, age 61, both hemispheres 913.0
2161 Male, age 80, both hemispheres 724.8
2840 Female, age 85, both hemispheres 613.9
1959 Male, age 76, both hemispheres 522.1
2449 Male, age 74, both hemispheres 488.8
2456 Female, age 91, both hemispheres 400.1

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1275.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1275.3
FF:10165-103B3 76 years, female 1527.8
FF:10182-103D2 60 years, female 1022.8
Pons
Scaled Tags Per Million: 812.6
FF:10033-101E6 18-54 years, mixed 812.6

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 441.6
Pig sample Sample description nTPM
Pons
nTPM: 441.7
Samples: 4

Max nTPM: 501.6
Min nTPM: 382.5
Sample A Female 423.0
Sample B Female 382.5
Sample C Male 501.6
Sample D Male 459.5

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 20.1
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 20.1
67936406 Antisense, RP_040604_02_C10, Mouse strain C57BL/6J (56 days, male) 24.5
79490110 Antisense, RP_070205_01_F04, Mouse strain C57BL/6J (56 days, male) 15.7
77620395 Antisense, RP_070205_01_F04, Mouse strain C57BL/6J (56 days, male) 13.6

Contact

  • NEWS ARTICLES
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.