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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 270.5
Min nTPM: 2.4
Std nTPM: 61.3
Median nTPM:
351_1
91 years, male
270.5
353_1
82 years, female
265.7
452_1
88 years, female
257.1
356_1
87 years, female
256.0
354_1
81 years, female
235.3
352_1
62 years, male
234.4
163_1
78 years, male
193.6
218_1
71 years, female
188.8
319_1
81 years, male
177.2
506_1
65 years, male
176.5
350_1
84 years, female
160.4
177_1
74 years, male
158.9
264_1
73 years, female
155.1
394_1
75 years, female
147.4
349_1
83 years, male
147.0
292_1
71 years, male
145.0
321_1
62 years, female
144.3
320_1
89 years, female
138.6
386_1
76 years, male
137.1
503_1
68 years, male
136.2
406_1
79 years, male
134.0
425_1
59 years, female
130.4
317_1
60 years, male
128.1
480_1
63 years, male
127.8
322_1
76 years, male
122.0
173_1
67 years, male
121.3
243_1
75 years, male
120.9
377_1
82 years, female
119.4
189_1
76 years, male
116.9
318_1
68 years, male
116.7
295_1
61 years, female
112.9
384_1
83 years, male
112.9
335_1
73 years, female
109.9
447_1
81 years, male
107.6
376_1
75 years, female
107.3
355_1
70 years, female
106.3
286_1
68 years, female
105.1
379_1
60 years, male
104.6
41_1
94 years, female
97.2
291_1
76 years, male
94.0
405_1
91 years, male
89.3
172_1
72 years, female
88.9
237_1
82 years, male
88.7
404_1
82 years, female
88.2
251_1
78 years, male
88.0
293_1
68 years, female
87.6
389_1
86 years, female
84.0
316_1
62 years, male
79.5
311_1
78 years, male
78.9
348_1
84 years, male
78.1
254_1
77 years, female
77.1
4_1
88 years, female
76.6
265_1
87 years, male
76.6
517_1
88 years, male
76.3
229_1
69 years, female
72.9
17_1
71 years, male
70.1
288_1
66 years, female
69.8
396_1
62 years, male
69.2
375_1
74 years, female
66.3
99_1
64 years, male
65.8
314_1
67 years, male
65.7
266_1
85 years, male
63.2
526_1
61 years, male
61.9
137_1
83 years, male
60.3
518_1
75 years, female
59.7
468_1
89 years, male
58.5
6_1
73 years, female
57.8
347_1
72 years, male
56.9
308_1
70 years, female
56.6
2_1
77 years, female
56.5
217_1
76 years, male
56.0
307_1
66 years, female
53.2
145_1
84 years, male
52.0
246_1
77 years, male
48.2
35_1
74 years, female
45.7
120_1
70 years, female
44.6
115_1
83 years, male
44.5
153_1
70 years, female
42.2
9_1
66 years, female
39.8
315_1
62 years, female
39.8
324_1
76 years, male
37.9
499_1
55 years, female
36.8
109_1
81 years, female
34.6
126_1
63 years, male
34.6
18_1
88 years, male
31.4
139_1
64 years, female
28.8
313_1
79 years, female
28.2
42_1
85 years, male
27.7
142_1
61 years, female
27.4
81_1
67 years, male
27.2
117_1
61 years, male
26.3
495_1
57 years, female
26.3
501_1
88 years, male
22.9
89_1
63 years, male
20.7
119_1
70 years, female
19.9
162_1
79 years, female
19.8
43_1
64 years, female
17.5
32_1
67 years, male
16.6
414_1
84 years, female
16.0
466_1
57 years, female
11.4
415_1
77 years, female
9.3
149_1
88 years, male
9.1
413_1
59 years, female
7.8
491_1
89 years, female
2.7
490_1
67 years, female
2.4
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
