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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:297.7 nTPM
HPA:297.7 nTPM
GTEx:303.3 nTPM
FANTOM5:129.8 Scaled Tags Per Million
Pig:187.0 nTPM
Mouse:916.0 nTPM
Allen mouse:2.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 297.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 290.1
2019 Male, age 18, unknown 303.7
2411 Female, age 72, unknown 298.3
1827 Male, age 72, unknown 293.8
2219 Male, age 76, both hemispheres 291.5
1870 Female, age 42, unknown 290.8
2586 Male, age 75, left hemisphere 288.6
2666 Male, age 74, left hemisphere 286.1
1833 Male, age 53, unknown 285.0
1830 Male, age 51, unknown 282.1
2828 Female, age 72, unknown 281.2
Dorsal raphe nucleus
nTPM: 290.9
2298 Female, age 72, unknown 301.1
1828 Male, age 53, unknown 294.5
2047 Male, age 72, unknown 289.9
2750 Male, age 76, both hemispheres 289.4
2016 Female, age 72, unknown 279.8
Inferior colliculus
nTPM: 294.6
2097 Female, age 72, unknown 304.3
1848 Female, age 42, unknown 293.0
1890 Male, age 53, unknown 292.9
2849 Male, age 72, unknown 288.4
Median raphe nucleus
nTPM: 288.5
2220 Male, age 76, midline 288.5
Pedunculopontine tegmental nucleus
nTPM: 292.8
1921 Female, age 85, both hemispheres 296.2
2334 Male, age 80, both hemispheres 295.9
2338 Male, age 61, both hemispheres 286.2
Periaquaductal grey, anterior
nTPM: 290.1
1947 Male, age 18, unknown 291.7
1795 Male, age 51, unknown 289.8
2502 Female, age 75, unknown 288.7
Periaquaductal grey, dorsal
nTPM: 283.7
1840 Male, age 53, unknown 287.8
2464 Female, age 72, unknown 284.4
2850 Male, age 76, both hemispheres 281.6
1831 Male, age 72, unknown 280.9
Periaquaductal grey, lateral
nTPM: 281.5
2272 Male, age 74, both hemispheres 284.3
2053 Male, age 18, unknown 282.3
2140 Male, age 76, both hemispheres 278.0
Pretectal area
nTPM: 296.7
2007 Male, age 72, unknown 318.0
1816 Male, age 51, unknown 311.5
1817 Female, age 42, unknown 311.4
1944 Female, age 72, unknown 302.1
1815 Male, age 53, unknown 300.5
2667 Female, age 75, unknown 294.1
2224 Female, age 72, unknown 290.3
2273 Male, age 74, both hemispheres 284.2
2316 Male, age 76, right hemisphere 284.0
2407 Male, age 75, both hemispheres 283.8
2825 Male, age 18, unknown 283.6
Red nucleus
nTPM: 292.7
1821 Female, age 72, unknown 314.6
2725 Female, age 75, unknown 296.3
2785 Male, age 18, unknown 295.7
2588 Male, age 74, left hemisphere 293.4
2503 Female, age 72, unknown 292.3
1865 Male, age 51, unknown 291.3
2227 Male, age 72, unknown 289.6
2769 Male, age 72, unknown 288.5
2823 Male, age 76, right hemisphere 288.2
2584 Male, age 75, left hemisphere 288.0
1904 Male, age 53, unknown 287.7
1954 Female, age 42, unknown 286.6
Substantia nigra
nTPM: 297.7
1851 Male, age 51, unknown 305.9
1889 Female, age 72, unknown 304.4
1916 Female, age 42, unknown 302.6
2241 Male, age 72, unknown 300.6
1941 Male, age 53, unknown 299.6
2665 Male, age 74, both hemispheres 299.5
2409 Female, age 72, unknown 295.7
2590 Female, age 75, unknown 291.7
2699 Male, age 18, unknown 290.7
2583 Male, age 75, right hemisphere 286.0
Superior colliculus
nTPM: 289.7
1796 Male, age 53, unknown 296.6
1895 Male, age 76, right hemisphere 296.1
2087 Female, age 72, unknown 293.3
2668 Female, age 75, unknown 293.2
2261 Male, age 18, unknown 289.1
2587 Male, age 74, left hemisphere 288.5
2664 Male, age 75, both hemispheres 286.5
1839 Male, age 51, unknown 285.7
1913 Female, age 42, unknown 285.1
1995 Male, age 72, unknown 282.5
Ventral tegmental area
nTPM: 293.2
2410 Female, age 72, unknown 302.7
1915 Female, age 42, unknown 300.3
2223 Female, age 72, unknown 296.0
2218 Male, age 76, both hemispheres 291.1
1942 Male, age 51, unknown 286.9
2021 Male, age 53, unknown 282.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 303.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 303.3
Samples: 139

Max nTPM: 758.5
Min nTPM: 130.0
Std nTPM: 110.3
Median nTPM: 281.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 758.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 692.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 689.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 608.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 544.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 524.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 516.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 513.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 513.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 502.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 484.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 480.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 476.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 462.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 444.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 444.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 428.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 412.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 406.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 401.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 395.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 390.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 390.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 387.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 377.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 368.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 366.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 361.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 361.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 356.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 354.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 352.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 351.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 349.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 347.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 346.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 346.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 340.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 340.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 339.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 338.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 334.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 332.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 329.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 327.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 323.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 323.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 322.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 321.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 320.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 316.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 312.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 311.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 310.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 309.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 308.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 305.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 303.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 302.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 298.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 297.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 294.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 294.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 293.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 291.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 289.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 289.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 285.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 282.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 281.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 276.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 275.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 274.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 273.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 269.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 268.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 266.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 265.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 264.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 264.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 264.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 260.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 256.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 253.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 253.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 253.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 247.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 247.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 246.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 246.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 244.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 242.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 241.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 240.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 237.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 233.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 233.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 231.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 231.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 230.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 229.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 228.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 226.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 224.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 222.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 220.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 219.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 218.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 218.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 216.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 215.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 214.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 213.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 211.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 210.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 210.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 209.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 207.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 203.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 203.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 202.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 201.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 200.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 199.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 198.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 191.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 189.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 188.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 185.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 185.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 182.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 180.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 179.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 177.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 173.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 171.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 158.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 156.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 130.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 129.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 129.8
FF:10158-103A5 76 years, female 129.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 187.0
Pig sample Sample description nTPM
Midbrain
nTPM: 168.3
Samples: 4

Max nTPM: 191.4
Min nTPM: 126.3
Sample A Female 189.2
Sample B Female 166.4
Sample C Male 191.4
Sample D Male 126.3
Periaqueductal gray
nTPM: 110.4
Samples: 3

Max nTPM: 123.7
Min nTPM: 98.1
Sample B Female 123.7
Sample C Male 109.4
Sample D Male 98.1
Substantia nigra
nTPM: 161.2
Samples: 4

Max nTPM: 253.3
Min nTPM: 106.6
Sample A Female 253.3
Sample B Female 142.4
Sample C Male 142.4
Sample D Male 106.6
Superior colliculi
nTPM: 186.9
Samples: 4

Max nTPM: 230.2
Min nTPM: 130.2
Sample A Female 222.6
Sample B Female 164.7
Sample C Male 230.2
Sample D Male 130.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 916.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 916.0
Samples: 4

Max nTPM: 978.6
Min nTPM: 869.4
Sample A Male 933.8
Sample B Male 869.4
Sample C Female 882.3
Sample D Female 978.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.6
69116709 Antisense, RP_050321_01_A05, Mouse strain C57BL/6J (56 days, male) 2.6

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